ITGB3BP and PIH1D2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ITGB3BP	PIH1D2
Gene Name		integrin beta 3 binding protein (beta3-endonexin)	PIH1 domain containing 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Signal Transducer Activity Protein C-terminus Binding	Ral GTPase Binding
	Biological Process	Mitotic Cell Cycle Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Mitotic Nuclear Division Cell Adhesion Signal Transduction CENP-A Containing Nucleosome Assembly Positive Regulation Of Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Cell Division Apoptotic Signaling Pathway
Pathways		Mitotic Prometaphase Signalling by NGF Chromosome Maintenance Cell death signalling via NRAGE, NRIF and NADE Separation of Sister Chromatids Deposition of new CENPA-containing nucleosomes at the centromere p75 NTR receptor-mediated signalling Mitotic Anaphase M Phase Cell Cycle, Mitotic Nucleosome assembly NRIF signals cell death from the nucleus Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: ACTN2 APP ARFIP2 CCNA2 COL4A3BP DDX24 ESR1 ITGB3 ITGB5 KDM1A KIFC3 MAPK6 MTA1 NFKB1 PIH1D2 RECQL5 RXRA RXRG SVIL THRA UBR7	11 interactors: DPH3 EIF4A2 GFAP IGF2BP3 ITGB3BP KRTAP12-4 MDFI MRFAP1L1 MVP RALA REL
Entrez ID		23421	120379
HPRD ID		09267	14021
Ensembl ID		ENSG00000142856	ENSG00000150773
Uniprot IDs		Q13352	E9PD82 Q8WWB5
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Response To Lipid Hormone-mediated Signaling Pathway Positive Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Cellular Metabolic Process Signaling Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Organic Cyclic Compound Positive Regulation Of Gene Expression Cell Communication Cellular Response To Lipid Regulation Of Branching Involved In Prostate Gland Morphogenesis Positive Regulation Of Cellular Biosynthetic Process Protein Homotetramerization Platelet Degranulation DNA-templated Transcription, Initiation Response To Steroid Hormone Response To Stimulus Signal Transduction Response To Organic Cyclic Compound Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Organelle Organization Response To Hormone Cellular Response To Hormone Stimulus Protein Tetramerization Cellular Response To Stimulus Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stress Negative Regulation Of Lipid Transport Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Transport Regulation Of RNA Metabolic Process Mating Behavior Tissue Development Organ Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Blood Coagulation Cell-matrix Adhesion Hemostasis	Negative Regulation Of RNA-directed RNA Polymerase Activity Positive Regulation Of Schwann Cell Proliferation Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cytokine Biosynthetic Process MRNA Transport Negative Regulation Of Biosynthetic Process RNA Transport RNA Localization Membrane Raft Localization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Protein Transport Regulation Of Cellular Process Bergmann Glial Cell Differentiation Cellular Response To Stimulus Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Binding Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Protein Autophosphorylation Regulation Of Translation Signal Transduction Positive Regulation Of Glial Cell Proliferation Regulation Of Neurotransmitter Uptake Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Negative Regulation Of Transferase Activity Regulation Of Cellular Localization Intermediate Filament Organization Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Protein Tyrosine Kinase Activity Trophoblast Giant Cell Differentiation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Signaling Astrocyte Development Cell Communication Cytoplasmic Sequestering Of Transcription Factor Dorsal/ventral Axis Specification
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