ITGB3BP

Gene Name		integrin beta 3 binding protein (beta3-endonexin)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Signal Transducer Activity Protein C-terminus Binding
	Biological Process	Mitotic Cell Cycle Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Mitotic Nuclear Division Cell Adhesion Signal Transduction CENP-A Containing Nucleosome Assembly Positive Regulation Of Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Cell Division Apoptotic Signaling Pathway
Pathways		Mitotic Prometaphase Signalling by NGF Chromosome Maintenance Cell death signalling via NRAGE, NRIF and NADE Separation of Sister Chromatids Deposition of new CENPA-containing nucleosomes at the centromere p75 NTR receptor-mediated signalling Mitotic Anaphase M Phase Cell Cycle, Mitotic Nucleosome assembly NRIF signals cell death from the nucleus Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-protein Interactions		21 interactors: ACTN2 APP ARFIP2 CCNA2 COL4A3BP DDX24 ESR1 ITGB3 ITGB5 KDM1A KIFC3 MAPK6 MTA1 NFKB1 PIH1D2 RECQL5 RXRA RXRG SVIL THRA UBR7
Entrez ID		23421
HPRD ID		09267
Ensembl ID		ENSG00000142856
Uniprot IDs		Q13352
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Response To Lipid Hormone-mediated Signaling Pathway Positive Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Cellular Metabolic Process Signaling Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Organic Cyclic Compound Positive Regulation Of Gene Expression Cell Communication Cellular Response To Lipid Regulation Of Branching Involved In Prostate Gland Morphogenesis Positive Regulation Of Cellular Biosynthetic Process Protein Homotetramerization Platelet Degranulation DNA-templated Transcription, Initiation Response To Steroid Hormone Response To Stimulus Signal Transduction Response To Organic Cyclic Compound Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Organelle Organization Response To Hormone Cellular Response To Hormone Stimulus Protein Tetramerization Cellular Response To Stimulus Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stress Negative Regulation Of Lipid Transport Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Transport Regulation Of RNA Metabolic Process Mating Behavior Tissue Development Organ Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Blood Coagulation Cell-matrix Adhesion Hemostasis
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