THRA and FOXJ1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		THRA	FOXJ1
Gene Name		thyroid hormone receptor, alpha	forkhead box J1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus
	Molecular Function	Steroid Receptor RNA Activator RNA Binding Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Thyroid Hormone Receptor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding TBP-class Protein Binding Protein Domain Specific Binding Chromatin DNA Binding Protein Complex Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Thyroid Hormone Binding	Transcription Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	Cartilage Condensation Ossification Regulation Of Thyroid Hormone Mediated Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Learning Or Memory Regulation Of Heart Contraction Female Courtship Behavior Response To Cold Hormone-mediated Signaling Pathway Gene Expression Positive Regulation Of Myotube Differentiation Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Erythrocyte Differentiation Intracellular Receptor Signaling Pathway Thyroid Gland Development Regulation Of Myeloid Cell Apoptotic Process Cytoplasmic Sequestering Of Transcription Factor Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Female Receptivity Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Lipid Catabolic Process Type I Pneumocyte Differentiation Negative Regulation Of DNA-templated Transcription, Initiation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Central Tolerance Induction Negative Regulation Of Germinal Center Formation Positive Regulation Of Central B Cell Tolerance Induction Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Transcription From RNA Polymerase II Promoter Humoral Immune Response Spermatogenesis Pattern Specification Process Brain Development Actin Cytoskeleton Organization Negative Regulation Of NF-kappaB Transcription Factor Activity Activation Of Rho GTPase Activity Negative Regulation Of T Cell Differentiation In Thymus Establishment Of Apical/basal Cell Polarity Metanephric Part Of Ureteric Bud Development Negative Regulation Of T Cell Proliferation Cilium Assembly Negative Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of B Cell Activation Leukocyte Migration Cilium Morphogenesis Lung Epithelium Development Epithelium Development Left/right Pattern Formation Glomerular Parietal Epithelial Cell Development Positive Regulation Of Lung Ciliated Cell Differentiation
Pathways		Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs		Liothyronine Levothyroxine Dextrothyroxine Liotrix 3,5-Dichloro-4-[(4-Hydroxy-3-Isopropylphenoxy)Phenylacetic Acid
Diseases
GWAS		White blood cell count ( 21738480)
Protein-Protein Interactions		56 interactors: AKAP13 AMOTL2 ARID5A BTG1 BUB3 C1D CCND1 CDK7 CLIC1 COPS2 CREB1 CREBBP CUL1 DAP3 ESR1 FOXJ1 FUS GRIP1 GTF2B HDAC2 HDAC3 ITGB3BP L3MBTL3 MED1 MED21 MED25 MEF2A NCOA1 NCOA6 NCOR1 NCOR2 NR0B2 NR2F1 NRIP1 NSD1 OASL PML POU2F1 PRKDC PTGES3 RANBP9 RGN RXRA RXRB RXRG SEPP1 SLC16A2 SRC SUV39H1 TBL1X TDG TRIM24 TRIP11 YWHAH YWHAQ ZBTB3	7 interactors: NMRAL1 OIP5 RPUSD1 SLC37A3 THRA TRMT6 TWF2
Entrez ID		7067	2302
HPRD ID		07185	03798
Ensembl ID		ENSG00000126351	ENSG00000129654
Uniprot IDs		P10827 Q6FH41	Q92949
PDB IDs		1NAV 2H77 2H79 3HZF 3ILZ 3JZB
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process DNA-templated Transcription, Initiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Rhythmic Process Organ Development Multicellular Organismal Development Regulation Of Cellular Process Anatomical Structure Development Developmental Process Cellular Response To Organic Substance Signal Transduction Chromosome Organization Signaling System Development	Regulation Of Microvillus Length Negative Regulation Of Protein Complex Assembly Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell Positive Regulation Of Female Receptivity Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Female Courtship Behavior Regulation Of Cell Projection Size Sequestering Of Actin Monomers Regulation Of Thyroid Hormone Mediated Signaling Pathway Regulation Of Protein Complex Assembly Regulation Of Female Receptivity
Tagcloud ?		accounts averages bimodality bxd bxh chr counted encode ganglion heritable hoxb idea inbred krt1 lod mapped neuregulin nnc1 opposed qtl qtls retina retinal striking subsidiary surprisingly thyroxine trait vertebrate	aldh1 ciliated columnar exposes gynaecological hgsc hgscs krt5 krt7 layered lef1 mem membraneous nests outgrowths oviduct oviductal oviducts pax2 pseudostratified rcn1 scout scouts stathmin stins tubal walthard wcn wcns
Tagcloud (Difference) ?		accounts averages bimodality bxd bxh chr counted encode ganglion heritable hoxb idea inbred krt1 lod mapped neuregulin nnc1 opposed qtl qtls retina retinal striking subsidiary surprisingly thyroxine trait vertebrate	aldh1 ciliated columnar exposes gynaecological hgsc hgscs krt5 krt7 layered lef1 mem membraneous nests outgrowths oviduct oviductal oviducts pax2 pseudostratified rcn1 scout scouts stathmin stins tubal walthard wcn wcns
Tagcloud (Intersection) ?