ITGB3BP and CERT1

Number of citations of the paper that reports this interaction (PubMedID 26496610)
0

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		ITGB3BP	CERT1
Description		integrin subunit beta 3 binding protein	ceramide transporter 1
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Membrane	Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Lipid Binding Kinase Activity Identical Protein Binding Phosphatidylinositol-4-phosphate Binding Ceramide Binding Ceramide Transfer Activity Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity
	Biological Process	Regulation Of DNA-templated Transcription Apoptotic Process Chromosome Segregation Cell Adhesion Signal Transduction CENP-A Containing Chromatin Assembly Positive Regulation Of Epithelial Cell Proliferation Cell Division Negative Regulation Of Epithelial Cell Apoptotic Process	Cell Morphogenesis In Utero Embryonic Development Heart Morphogenesis Ceramide Metabolic Process Lipid Transport Muscle Contraction Immune Response Mitochondrion Organization Endoplasmic Reticulum Organization Signal Transduction Cell Population Proliferation Response To Endoplasmic Reticulum Stress ER To Golgi Ceramide Transport Ceramide Transport Lipid Homeostasis Intermembrane Lipid Transfer Intermembrane Sphingolipid Transfer Ceramide 1-phosphate Transport
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal NRIF signals cell death from the nucleus NRIF signals cell death from the nucleus Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494)
Interacting Genes		42 interacting genes: ACTN2 ANKRD11 APP ARFIP2 C14orf119 CCNA2 CERT1 DDX24 EFHC1 ESR1 GTPBP3 HSF2BP ITGB3 ITGB5 KDM1A KIAA0930 KIFC3 LRRK2 MAPK6 MAPK9 MEIS2 MEOX2 MSGN1 MTA1 NFKB1 NRDE2 NTAQ1 PBX3 PIH1D2 PIK3R3 PKNOX1 RECQL5 RXRA RXRG SNAPC5 SUOX SVIL THRA TRIML2 UBR7 USHBP1 USP20	18 interacting genes: ACTL8 AQP2 ARL6IP1 BSND CBS COL4A3 CSNK1G2 FTSJ1 ITGB3BP MINAR1 PM20D2 POM121 REEP6 RTN3 RTN4 SMU1 STX2 TGM2
Entrez ID		23421	10087
HPRD ID		09267	05246
Ensembl ID		ENSG00000142856	ENSG00000113163
Uniprot IDs		Q13352	A0A2R8Y7C5 Q9Y5P4
PDB IDs		7PB8 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH	2E3M 2E3N 2E3O 2E3P 2E3Q 2E3R 2E3S 2RSG 2Z9Y 2Z9Z 3H3Q 3H3R 3H3S 3H3T 4HHV 5JJD 5ZYG 5ZYH 5ZYI 5ZYJ 5ZYK 5ZYL 5ZYM 6IEZ 6IF0 6J0O 6J81
Enriched GO Terms of Interacting Partners?		Sequence-specific DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-templated Transcription Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Transcription Regulator Complex DNA-binding Transcription Factor Activity NF-kappaB P50/p65 Complex Positive Regulation Of Transcription By RNA Polymerase II Nuclear Receptor Activity Transcription By RNA Polymerase II Chromatin Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Positive Regulation Of Protein Autoubiquitination Nuclear Steroid Receptor Activity Chromatin Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Retinoic Acid Receptor Signaling Pathway RNA Metabolic Process Hormone-mediated Signaling Pathway Negative Regulation Of MiRNA Transcription Intracellular Signaling Cassette Cellular Response To Oxygen-containing Compound Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Identical Protein Binding Regulation Of MiRNA Metabolic Process Regulation Of Macrophage Derived Foam Cell Differentiation Nucleic Acid Metabolic Process Intracellular Signal Transduction Regulation Of Thyroid Hormone Receptor Signaling Pathway Regulation Of Protein Autoubiquitination Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Retinoic Acid-responsive Element Binding Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of RNA Metabolic Process Response To Mechanical Stimulus Positive Regulation Of Protein Ubiquitination Cellular Response To Nicotine Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Cellular Response To Manganese Ion Intracellular Receptor Signaling Pathway	Endoplasmic Reticulum Tubular Network Formation Endoplasmic Reticulum Tubular Network Membrane Organization Endoplasmic Reticulum Organization Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Tubular Network Organization S-adenosyl-L-methionine Binding Endoplasmic Reticulum Tubular Network Regulation Of Vasculature Development Regulation Of Angiogenesis Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Amyloid-beta Formation Endoplasmic Reticulum Peptide Dopaminyltransferase Activity Histone Serotonyltransferase Activity Peptide Histaminyltransferase Activity Protein-glutamine Glutaminase Activity Peptide Noradrenalinyltransferase Activity Peptide Serotonyltransferase Activity Histone Dopaminyltransferase Activity Regulation Of Amyloid-beta Formation TRNA (guanosine(34)-2'-O)-methyltransferase Activity Negative Regulation Of Vasculogenesis Positive Regulation Of ERBB3 Signaling Pathway Cell Adhesion Involved In Sprouting Angiogenesis Para-aminobenzoyl-glutamate Hydrolase Activity Regulation Of Amyloid Precursor Protein Catabolic Process Lumenal Side Of Membrane Glycerol Transmembrane Transporter Activity Basolateral Plasma Membrane Cysteine Biosynthetic Process From Serine Cystathionine Beta-synthase Activity Apoptotic Process Protein Deamination Wobble Position Ribose Methylation TRNA 2'-O-methyltransferase Activity Folic Acid Catabolic Process Cell Death Programmed Cell Death
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