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EXOC7 and TRAF4
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
EXOC7
TRAF4
Gene Name
exocyst complex component 7
TNF receptor-associated factor 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Exocyst
Microtubule Organizing Center
Cytosol
Plasma Membrane
Membrane
Growth Cone Membrane
Centriolar Satellite
Nucleus
Cytoplasm
Cytoskeleton
Plasma Membrane
Tight Junction
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
DNA Binding
Ubiquitin-protein Transferase Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
WW Domain Binding
Biological Process
Exocytosis
Organelle Organization
Protein Transport
Cellular Protein Metabolic Process
Membrane Organization
Apoptotic Process
Signal Transduction
Activation Of NF-kappaB-inducing Kinase Activity
Respiratory Gaseous Exchange
Protein Ubiquitination
Respiratory Tube Development
Regulation Of Apoptotic Process
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of JNK Cascade
Positive Regulation Of Protein Homodimerization Activity
Pathways
Peptide hormone metabolism
Cargo trafficking to the periciliary membrane
Organelle biogenesis and maintenance
Translocation of GLUT4 to the plasma membrane
VxPx cargo-targeting to cilium
Assembly of the primary cilium
Insulin processing
Drugs
Diseases
GWAS
Protein-Protein Interactions
26 interactors:
AKTIP
ARFGEF2
ARPC1A
BBS1
BBS2
BBS4
CCDC85B
CDC5L
DISC1
DLG3
DTNBP1
EXOC2
EXOC4
GRIN2B
HGS
IFT20
KXD1
PRPF19
RALA
RHOQ
RTN4IP1
SMARCE1
SSC5D
TRAF4
USHBP1
ZC3H14
69 interactors:
ALKBH4
ARNT2
BAHD1
BANP
BCKDK
BCL6B
BYSL
CALCOCO2
CBL
CBLC
CCHCR1
CENPE
CHUK
DTX3
EXOC7
FBXL18
FTH1
GORASP2
GPRASP1
HOMEZ
IRAK1
ISYNA1
KANSL1
KDM1A
KRT31
KRT40
LTBR
MAGED1
MAP3K4
MRPL28
NCF1
NGFR
NGFRAP1
NOS1AP
NPAS2
PDE4DIP
PKD1P1
PLSCR1
PSMC3
QARS
REXO1L6P
RNF114
RPS6KB1
SIGLEC7
SMURF1
SMURF2
SORBS2
SPDL1
SUMO1
TARBP2
TBC1D7
TBC1D8
TGFB1I1
TICAM1
TNFRSF4
TP53BP2
TRAF6
TRIM37
TYK2
UBE2I
UBL4A
UBL4B
USP7
WBP11
WWP1
WWP2
ZNF3
ZNF512B
ZNF581
Entrez ID
23265
9618
HPRD ID
16292
03915
Ensembl ID
ENSG00000182473
ENSG00000076604
Uniprot IDs
B4DJ07
B5MCY9
Q63HP7
Q9UPT5
Q9BUZ4
PDB IDs
2EOD
2YUC
4M4E
Enriched GO Terms of Interacting Partners
?
Cellular Localization
Post-Golgi Vesicle-mediated Transport
Golgi To Plasma Membrane Transport
Vesicle-mediated Transport
Protein Localization
Organelle Organization
Nonmotile Primary Cilium Assembly
Cell Projection Morphogenesis
Cell Part Morphogenesis
Membrane Organization
Establishment Of Localization In Cell
Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway
Protein Transport
Photoreceptor Cell Maintenance
Cell Morphogenesis
Regulation Of Cell Projection Assembly
Golgi Vesicle Transport
Establishment Of Protein Localization
Intracellular Transport
Cell Projection Organization
Transport
Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Cilium Assembly
Leptin-mediated Signaling Pathway
Retina Homeostasis
Cellular Pigmentation
Cellular Protein Localization
Cilium Organization
Nervous System Development
Negative Regulation Of Appetite
Cytoplasmic Transport
Signaling
Cilium Morphogenesis
Endomembrane System Organization
Cellular Response To Leptin Stimulus
Protein Localization To Cilium
Cell Communication
Cytoskeleton Organization
Regulation Of Microtubule-based Movement
Generation Of Neurons
Regulation Of Cell Projection Organization
Striatum Development
Response To Leptin
Signal Transduction
Protein Localization To Organelle
Neurogenesis
Cell Projection Assembly
Regulation Of Response To Food
Developmental Process
Regulation Of Appetite
Protein Modification By Small Protein Conjugation
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Protein Ubiquitination
Regulation Of Gene Expression
Regulation Of Signal Transduction
Regulation Of Metabolic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Signaling
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Response To Growth Factor
Regulation Of Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Ubiquitin-dependent SMAD Protein Catabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Signal Transduction
Cellular Protein Modification Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Protein Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Growth Factor Stimulus
Regulation Of Innate Immune Response
Negative Regulation Of Transcription, DNA-templated
Response To Organic Substance
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Programmed Cell Death
Proteolysis Involved In Cellular Protein Catabolic Process
Response To Cytokine
Cellular Protein Catabolic Process
Cell Death
Death
Protein Metabolic Process
Cellular Response To Organic Substance
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Protein Catabolic Process
Tagcloud
?
bcr
cart
cd40
cd54
cd95
ciap2
define
dr3
driven
effector
engagement
fas
icam
linking
mapk
mapkapk
minimal
p38
permeable
perturbed
potentiating
requirement
responsive
sb203580
selectively
stimulates
tonsillar
traf1
unaffected
Tagcloud (Difference)
?
bcr
cart
cd40
cd54
cd95
ciap2
define
dr3
driven
effector
engagement
fas
icam
linking
mapk
mapkapk
minimal
p38
permeable
perturbed
potentiating
requirement
responsive
sb203580
selectively
stimulates
tonsillar
traf1
unaffected
Tagcloud (Intersection)
?