EXOC7 and SAPCD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EXOC7	SAPCD2
Description		exocyst complex component 7	suppressor APC domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Microtubule Organizing Center Cytosol Plasma Membrane Membrane Midbody Growth Cone Membrane Centriolar Satellite Flemming Body	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Membrane Apical Plasma Membrane Apical Junction Complex Apical Cortex Anchoring Junction
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein-macromolecule Adaptor Activity	Protein Binding
	Biological Process	Mitotic Cytokinesis Exocytosis Vesicle Docking Involved In Exocytosis Protein Transport Regulation Of Macroautophagy Protein Transmembrane Transport Membrane Fission Vesicle Tethering Involved In Exocytosis Positive Regulation Of Mitotic Cytokinetic Process Regulation Of Entry Of Bacterium Into Host Cell	Establishment Of Mitotic Spindle Orientation Positive Regulation Of Cell Population Proliferation Cell Division Regulation Of Establishment Of Planar Polarity Symmetric Cell Division Negative Regulation Of Protein Localization To Cell Cortex
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654)	Aspartate aminotransferase levels ( 33547301) Platelet count ( 32888494)
Interacting Genes		40 interacting genes: AKTIP ARFGEF2 ARPC1A BBS1 BBS2 BBS4 CCDC85B CCHCR1 CDC5L CT55 DISC1 DLG3 EXOC2 EXOC4 FBXO28 GRIN2B HGS IFT20 KDM1A KIFC3 KXD1 MSGN1 NRIP1 OLIG2 PKNOX1 PLEKHF2 PRPF19 RALA RALY RHOQ RTN4IP1 SAPCD2 SMARCE1 SNAPIN SSC5D TRAF4 TRIM54 USHBP1 YAE1 ZC3H14	13 interacting genes: AIRIM ATF4 BFSP2 CYSRT1 EXOC7 GMNN GPRASP2 KRT3 KRTAP1-3 MDFI RALBP1 USHBP1 VCL
Entrez ID		23265	89958
HPRD ID		16292	12943
Ensembl ID		ENSG00000182473	ENSG00000186193
Uniprot IDs		B4DJ07 B5MCY9 Q9UPT5	Q86UD0
PDB IDs
Enriched GO Terms of Interacting Partners?		BBSome Golgi To Plasma Membrane Transport Vesicle-mediated Transport To The Plasma Membrane Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Vesicle-mediated Transport Localization Within Membrane Cytoskeleton Intracellular Protein Localization Cellular Localization Protein Transport Establishment Of Protein Localization Post-Golgi Vesicle-mediated Transport Striatum Development Regulation Of Cilium Beat Frequency Non-motile Cilium Assembly Microtubule-based Process Brain Morphogenesis Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Endosome Organization Cerebral Cortex Development Flemming Body Protein Binding Regulation Of Cilium Movement Organelle Localization Exocytosis Centrosome Photoreceptor Cell Maintenance Motile Cilium Regulation Of Lysosome Size BORC Complex Membrane Fission Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Cell Projection Organization Cytoplasm Vesicle Tethering Involved In Exocytosis Lysosomal Transport Leptin-mediated Signaling Pathway Regulation Of Microtubule-based Movement Ciliary Membrane Regulation Of Endosome Size Endosome To Lysosome Transport Cilium Assembly Negative Regulation Of Appetite Establishment Of Organelle Localization Protein Localization To Cilium DNA Replication Factor A Complex Cytoplasmic Side Of Lysosomal Membrane Golgi Vesicle Transport
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