EXOC7 and ARFGEF2

Number of citations of the paper that reports this interaction (PMID 15705715)
15

Data Source:
HPRD (two hybrid)

		EXOC7	ARFGEF2
Gene Name		exocyst complex component 7	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Microtubule Organizing Center Cytosol Plasma Membrane Membrane Growth Cone Membrane Centriolar Satellite	Golgi Membrane Trans-Golgi Network Microtubule Organizing Center Cytosol Axonemal Microtubule Membrane Cytoplasmic Membrane-bounded Vesicle Cell Junction Cytoplasmic Vesicle Asymmetric Synapse Symmetric Synapse Dendritic Spine Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Myosin Binding Protein Kinase A Regulatory Subunit Binding GABA Receptor Binding
	Biological Process	Exocytosis Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization	Receptor Recycling Exocytosis Golgi To Plasma Membrane Transport Endosome Organization Endomembrane System Organization Protein Transport Vesicle-mediated Transport Regulation Of ARF Protein Signal Transduction Positive Regulation Of Tumor Necrosis Factor Production Intracellular Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing	Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: AKTIP ARFGEF2 ARPC1A BBS1 BBS2 BBS4 CCDC85B CDC5L DISC1 DLG3 DTNBP1 EXOC2 EXOC4 GRIN2B HGS IFT20 KXD1 PRPF19 RALA RHOQ RTN4IP1 SMARCE1 SSC5D TRAF4 USHBP1 ZC3H14	9 interactors: ARFGEF1 EXOC7 GABRB1 GABRB2 GABRB3 PNPLA2 PRKAR1A PRKAR2A PRPF40A
Entrez ID		23265	10564
HPRD ID		16292	09250
Ensembl ID		ENSG00000182473	ENSG00000124198
Uniprot IDs		B4DJ07 B5MCY9 Q63HP7 Q9UPT5	Q59FR3 Q86TH5 Q9Y6D5
PDB IDs			3L8N 3SWV
Enriched GO Terms of Interacting Partners?		Cellular Localization Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Vesicle-mediated Transport Protein Localization Organelle Organization Nonmotile Primary Cilium Assembly Cell Projection Morphogenesis Cell Part Morphogenesis Membrane Organization Establishment Of Localization In Cell Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Protein Transport Photoreceptor Cell Maintenance Cell Morphogenesis Regulation Of Cell Projection Assembly Golgi Vesicle Transport Establishment Of Protein Localization Intracellular Transport Cell Projection Organization Transport Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Cilium Assembly Leptin-mediated Signaling Pathway Retina Homeostasis Cellular Pigmentation Cellular Protein Localization Cilium Organization Nervous System Development Negative Regulation Of Appetite Cytoplasmic Transport Signaling Cilium Morphogenesis Endomembrane System Organization Cellular Response To Leptin Stimulus Protein Localization To Cilium Cell Communication Cytoskeleton Organization Regulation Of Microtubule-based Movement Generation Of Neurons Regulation Of Cell Projection Organization Striatum Development Response To Leptin Signal Transduction Protein Localization To Organelle Neurogenesis Cell Projection Assembly Regulation Of Response To Food Developmental Process Regulation Of Appetite	Cellular Response To Histamine Response To Histamine Cellular Response To Ammonium Ion Cellular Response To Organonitrogen Compound Negative Regulation Of CAMP-dependent Protein Kinase Activity Response To Ammonium Ion Response To Organonitrogen Compound Chloride Transmembrane Transport Regulation Of CAMP-dependent Protein Kinase Activity Activation Of Protein Kinase A Activity Chloride Transport Renal Water Homeostasis Innervation Cellular Response To Glucagon Stimulus Inner Ear Receptor Cell Development Inorganic Anion Transport Water Transport Fluid Transport Cochlea Development Activation Of Phospholipase C Activity Multicellular Organismal Water Homeostasis Response To Glucagon Positive Regulation Of Phospholipase C Activity Transmembrane Transport Inner Ear Receptor Cell Differentiation Water Homeostasis Mechanoreceptor Differentiation Cellular Response To Organic Substance Cellular Response To Organic Cyclic Compound Positive Regulation Of Phospholipase Activity Anion Transmembrane Transport Positive Regulation Of Protein Glycosylation In Golgi Transport Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Nerve Development Renal System Process Synaptic Transmission Negative Regulation Of Protein Serine/threonine Kinase Activity Response To Organic Substance Energy Reserve Metabolic Process Positive Regulation Of Protein Glycosylation Sensory Perception Of Sound Anion Transport Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Acylglycerol Acyl-chain Remodeling Negative Regulation Of Neuron Apoptotic Process Sensory Perception Of Mechanical Stimulus
Tagcloud ?			13q33 15q26 20q13 22q11 already c20orf199 candidate chromosomes copy cse1l ddx27 deficiency duplications gh hemizygous homozygous individuals integrin investigations itgbl1 kcnb1 mb oligonucleotide predispose ptgis remaining snord12 unreported znfx1
Tagcloud (Difference) ?			13q33 15q26 20q13 22q11 already c20orf199 candidate chromosomes copy cse1l ddx27 deficiency duplications gh hemizygous homozygous individuals integrin investigations itgbl1 kcnb1 mb oligonucleotide predispose ptgis remaining snord12 unreported znfx1
Tagcloud (Intersection) ?