EXOC7 and ARPC1A

Number of citations of the paper that reports this interaction (PubMedID 17086175)
0

Data Source:
HPRD (in vitro, in vivo)

		EXOC7	ARPC1A
Description		exocyst complex component 7	actin related protein 2/3 complex subunit 1A
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Microtubule Organizing Center Cytosol Plasma Membrane Membrane Midbody Growth Cone Membrane Centriolar Satellite Flemming Body	Nucleus Cytoplasm Cytosol Cytoskeleton Arp2/3 Protein Complex Actin Cytoskeleton Site Of Double-strand Break Muscle Cell Projection Membrane Synapse Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein-macromolecule Adaptor Activity	Actin Binding Protein Binding Actin Filament Binding
	Biological Process	Mitotic Cytokinesis Exocytosis Vesicle Docking Involved In Exocytosis Protein Transport Regulation Of Macroautophagy Protein Transmembrane Transport Membrane Fission Vesicle Tethering Involved In Exocytosis Positive Regulation Of Mitotic Cytokinetic Process Regulation Of Entry Of Bacterium Into Host Cell	Actin Cytoskeleton Organization Arp2/3 Complex-mediated Actin Nucleation
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654)	Alcohol consumption ( 31358974) Dehydroepiandrosterone sulphate levels ( 21533175) Facial emotion recognition (sad faces) ( 28608620) Glycated hemoglobin levels ( 34059833) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Medication use (calcium channel blockers) ( 31015401) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum metabolite levels ( 23093944) Ticagrelor levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875)
Interacting Genes		40 interacting genes: AKTIP ARFGEF2 ARPC1A BBS1 BBS2 BBS4 CCDC85B CCHCR1 CDC5L CT55 DISC1 DLG3 EXOC2 EXOC4 FBXO28 GRIN2B HGS IFT20 KDM1A KIFC3 KXD1 MSGN1 NRIP1 OLIG2 PKNOX1 PLEKHF2 PRPF19 RALA RALY RHOQ RTN4IP1 SAPCD2 SMARCE1 SNAPIN SSC5D TRAF4 TRIM54 USHBP1 YAE1 ZC3H14	2 interacting genes: ERCC6 EXOC7
Entrez ID		23265	10552
HPRD ID		16292	07252
Ensembl ID		ENSG00000182473	ENSG00000241685
Uniprot IDs		B4DJ07 B5MCY9 Q9UPT5	Q92747 V9HVZ6
PDB IDs			6YW7
Enriched GO Terms of Interacting Partners?		BBSome Golgi To Plasma Membrane Transport Vesicle-mediated Transport To The Plasma Membrane Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Vesicle-mediated Transport Localization Within Membrane Cytoskeleton Intracellular Protein Localization Cellular Localization Protein Transport Establishment Of Protein Localization Post-Golgi Vesicle-mediated Transport Striatum Development Regulation Of Cilium Beat Frequency Non-motile Cilium Assembly Microtubule-based Process Brain Morphogenesis Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Endosome Organization Cerebral Cortex Development Flemming Body Protein Binding Regulation Of Cilium Movement Organelle Localization Exocytosis Centrosome Photoreceptor Cell Maintenance Motile Cilium Regulation Of Lysosome Size BORC Complex Membrane Fission Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Cell Projection Organization Cytoplasm Vesicle Tethering Involved In Exocytosis Lysosomal Transport Leptin-mediated Signaling Pathway Regulation Of Microtubule-based Movement Ciliary Membrane Regulation Of Endosome Size Endosome To Lysosome Transport Cilium Assembly Negative Regulation Of Appetite Establishment Of Organelle Localization Protein Localization To Cilium DNA Replication Factor A Complex Cytoplasmic Side Of Lysosomal Membrane Golgi Vesicle Transport	B-WICH Complex DNA Protection Transcription Elongation By RNA Polymerase I Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Response To Superoxide Pyrimidine Dimer Repair Response To Oxygen Radical Positive Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Regulation Of Entry Of Bacterium Into Host Cell Growth Cone Membrane Vesicle Tethering Involved In Exocytosis Positive Regulation Of Mitotic Cytokinetic Process Double-strand Break Repair Via Classical Nonhomologous End Joining Single Strand Break Repair Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Transcription By RNA Polymerase III Regulation Of Cell Cycle Process ATP-dependent Chromatin Remodeler Activity RNA Polymerase Binding ATP-dependent DNA Damage Sensor Activity Protein Tyrosine Kinase Activator Activity Chromatin-protein Adaptor Activity Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis Exocyst Transcription Elongation Factor Complex Positive Regulation Of Peptidyl-serine Phosphorylation Response To UV-B Regulation Of Peptidyl-serine Phosphorylation Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Defense Response To Virus By Host Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Positive Regulation Of Transcription By RNA Polymerase I Response To X-ray ATP-dependent Activity, Acting On DNA Regulation Of Cell Cycle Flemming Body Vesicle Tethering Negative Regulation Of DNA Repair Base-excision Repair Site Of DNA Damage Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Photoreceptor Cell Maintenance Regulation Of Defense Response To Virus By Host Regulation Of Transcription By RNA Polymerase I DNA Helicase Activity Negative Regulation Of Double-strand Break Repair Positive Regulation Of Cytokinesis Membrane Fission Vesicle Docking Involved In Exocytosis
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