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EXOC7 and HGS
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid, two hybrid)
HPRD
(two hybrid)
EXOC7
HGS
Gene Name
exocyst complex component 7
hepatocyte growth factor-regulated tyrosine kinase substrate
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Exocyst
Microtubule Organizing Center
Cytosol
Plasma Membrane
Membrane
Growth Cone Membrane
Centriolar Satellite
Cytoplasm
Endosome
Early Endosome
Cytosol
Secretory Granule
Early Endosome Membrane
Multivesicular Body Membrane
Intracellular Membrane-bounded Organelle
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Protein Binding
Protein Domain Specific Binding
Metal Ion Binding
Biological Process
Exocytosis
Organelle Organization
Protein Transport
Cellular Protein Metabolic Process
Membrane Organization
Protein Targeting To Lysosome
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Cell Proliferation
Endosome To Lysosome Transport
Membrane Invagination
Positive Regulation Of Gene Expression
Endosomal Transport
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Protein Catabolic Process
Negative Regulation Of JAK-STAT Cascade
Membrane Organization
Protein Localization To Membrane
Positive Regulation Of Exosomal Secretion
Pathways
Peptide hormone metabolism
Cargo trafficking to the periciliary membrane
Organelle biogenesis and maintenance
Translocation of GLUT4 to the plasma membrane
VxPx cargo-targeting to cilium
Assembly of the primary cilium
Insulin processing
Signaling by EGFR
EGFR downregulation
Endosomal Sorting Complex Required For Transport (ESCRT)
Signaling by EGFR in Cancer
Signaling by Ligand-Responsive EGFR Variants in Cancer
Signaling by Overexpressed Wild-Type EGFR in Cancer
Signaling by EGFRvIII in Cancer
Drugs
Diseases
GWAS
Eye color traits (
20463881
)
Protein-Protein Interactions
26 interactors:
AKTIP
ARFGEF2
ARPC1A
BBS1
BBS2
BBS4
CCDC85B
CDC5L
DISC1
DLG3
DTNBP1
EXOC2
EXOC4
GRIN2B
HGS
IFT20
KXD1
PRPF19
RALA
RHOQ
RTN4IP1
SMARCE1
SSC5D
TRAF4
USHBP1
ZC3H14
138 interactors:
ABI2
ACLY
AHCYL1
APC
APLP2
APP
ARFIP2
ARL6IP1
ATP1A1
ATP2A2
ATXN1L
BCAS2
BEGAIN
BRINP3
BSG
CASK
CBS
CCDC103
CCDC114
CCDC33
CEP55
CEP57L1
CLTC
CRMP1
CSTF2
CSTF2T
CTTNBP2NL
DAZAP2
DCTN2
DECR1
DGCR6
DLG4
EGFR
EHMT2
EPS15
ESRRG
EXOC7
EXOC8
GFAP
GFI1B
GGA2
GKAP1
HAP1
HNRNPDL
HSPA8
IL2RB
IL4R
ILKAP
ING5
INTS4
JAKMIP2
KRT15
KRT18
KRT19
KRT31
KRT38
KRT40
KRT6A
LDOC1
LINC00265
LITAF
LURAP1
LYST
MAGEB4
MAP3K10
MAP3K7
MAPK1IP1L
MARK4
MAT2A
MED7
MEST
MET
MIF4GD
MKNK1
MRFAP1L1
MTHFD1L
NDC80
NEDD4
NEDD4L
NF2
NMI
NPAS2
NUP54
OSBPL5
P4HA3
PAK1
PEF1
PELP1
PFKM
PIK3R1
PITX1
PLD3
POGZ
PPP1R16A
PPP1R7
PTCD3
RHOBTB3
RPS3A
RSU1
SCAMP3
SCRN1
SF3B3
SMAD2
SMAD3
SMAD5
SNAP25
SNX1
SNX5
SNX7
STAM
STAM2
STXBP1
SUMO1
SUN2
TADA2A
TIMMDC1
TJP2
TMCC2
TOM1L1
TRAK1
TRAP1
TSG101
TUBB
TUBB2A
UBA1
UBA52
UBB
UBC
UBE2I
UBE4B
UBQLN1
UBQLN4
USHBP1
VMP1
VPS37A
VPS37C
VPS37D
ZNF302
Entrez ID
23265
9146
HPRD ID
16292
05085
Ensembl ID
ENSG00000182473
ENSG00000185359
Uniprot IDs
B4DJ07
B5MCY9
Q63HP7
Q9UPT5
O14964
PDB IDs
2D3G
3F1I
3OBQ
3ZYQ
4AVX
Enriched GO Terms of Interacting Partners
?
Cellular Localization
Post-Golgi Vesicle-mediated Transport
Golgi To Plasma Membrane Transport
Vesicle-mediated Transport
Protein Localization
Organelle Organization
Nonmotile Primary Cilium Assembly
Cell Projection Morphogenesis
Cell Part Morphogenesis
Membrane Organization
Establishment Of Localization In Cell
Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway
Protein Transport
Photoreceptor Cell Maintenance
Cell Morphogenesis
Regulation Of Cell Projection Assembly
Golgi Vesicle Transport
Establishment Of Protein Localization
Intracellular Transport
Cell Projection Organization
Transport
Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Cilium Assembly
Leptin-mediated Signaling Pathway
Retina Homeostasis
Cellular Pigmentation
Cellular Protein Localization
Cilium Organization
Nervous System Development
Negative Regulation Of Appetite
Cytoplasmic Transport
Signaling
Cilium Morphogenesis
Endomembrane System Organization
Cellular Response To Leptin Stimulus
Protein Localization To Cilium
Cell Communication
Cytoskeleton Organization
Regulation Of Microtubule-based Movement
Generation Of Neurons
Regulation Of Cell Projection Organization
Striatum Development
Response To Leptin
Signal Transduction
Protein Localization To Organelle
Neurogenesis
Cell Projection Assembly
Regulation Of Response To Food
Developmental Process
Regulation Of Appetite
Establishment Of Localization In Cell
Cellular Localization
Viral Protein Processing
Protein Localization
Intracellular Transport
Membrane Organization
Endosomal Transport
Establishment Of Protein Localization
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Protein Transport
Regulation Of ERBB Signaling Pathway
Virion Assembly
Intracellular Transport Of Virus
Viral Process
Cellular Protein Localization
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Vesicle-mediated Transport
Viral Life Cycle
Cell Cycle Process
Organelle Organization
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Mitotic Cell Cycle
Mitotic Cell Cycle Process
Transport
Post-Golgi Vesicle-mediated Transport
Transforming Growth Factor Beta Receptor Signaling Pathway
Cellular Metabolic Process
Gene Expression
Cell Cycle
Vesicle Organization
Secretion By Cell
Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
ERBB Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Intracellular Protein Transport
Transcription Initiation From RNA Polymerase II Promoter
Cellular Process
Cellular Response To Transforming Growth Factor Beta Stimulus
Posttranscriptional Regulation Of Gene Expression
Secretion
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Transcription From RNA Polymerase II Promoter
Response To Transforming Growth Factor Beta
Regulation Of Protein Catabolic Process
JNK Cascade
Response To Organic Substance
Tagcloud
?
adjustments
associates
confounders
continued
cubic
cv
geriatric
gnri
handgrip
hemodialysis
hospitalization
hospitalizations
malnutrition
mhd
mis
nutritional
observational
outpatients
qol
scales
sf
sf36
spline
sua
tertile
trends
upcoming
uric
y
Tagcloud (Difference)
?
adjustments
associates
confounders
continued
cubic
cv
geriatric
gnri
handgrip
hemodialysis
hospitalization
hospitalizations
malnutrition
mhd
mis
nutritional
observational
outpatients
qol
scales
sf
sf36
spline
sua
tertile
trends
upcoming
uric
y
Tagcloud (Intersection)
?