EXOC7 and RALA

Number of citations of the paper that reports this interaction (PMID 11406615)
35

Data Source:
HPRD (in vitro)

		EXOC7	RALA
Gene Name		exocyst complex component 7	v-ral simian leukemia viral oncogene homolog A (ras related)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Microtubule Organizing Center Cytosol Plasma Membrane Membrane Growth Cone Membrane Centriolar Satellite	Plasma Membrane Focal Adhesion Cell Surface Endocytic Vesicle Midbody Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	GTPase Activity Protein Binding GTP Binding Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding
	Biological Process	Exocytosis Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization	Cytokinesis Exocytosis Chemotaxis Signal Transduction Ras Protein Signal Transduction Viral Process Regulation Of Exocytosis Actin Cytoskeleton Reorganization Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Filopodium Assembly Membrane Raft Localization Membrane Organization
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing	Signalling to ERKs Signalling by NGF Signalling to RAS p38MAPK events Translocation of GLUT4 to the plasma membrane NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: AKTIP ARFGEF2 ARPC1A BBS1 BBS2 BBS4 CCDC85B CDC5L DISC1 DLG3 DTNBP1 EXOC2 EXOC4 GRIN2B HGS IFT20 KXD1 PRPF19 RALA RHOQ RTN4IP1 SMARCE1 SSC5D TRAF4 USHBP1 ZC3H14	32 interactors: ARF1 CALM1 CNKSR2 EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA HRAS LRPAP1 LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RAP1A RAP2A RAP2B RASSF5 REPS1 RGL2 RGL4 SMAD4 YBX3
Entrez ID		23265	5898
HPRD ID		16292	01549
Ensembl ID		ENSG00000182473	ENSG00000006451
Uniprot IDs		B4DJ07 B5MCY9 Q63HP7 Q9UPT5	P11233
PDB IDs			1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV
Enriched GO Terms of Interacting Partners?		Cellular Localization Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Vesicle-mediated Transport Protein Localization Organelle Organization Nonmotile Primary Cilium Assembly Cell Projection Morphogenesis Cell Part Morphogenesis Membrane Organization Establishment Of Localization In Cell Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Protein Transport Photoreceptor Cell Maintenance Cell Morphogenesis Regulation Of Cell Projection Assembly Golgi Vesicle Transport Establishment Of Protein Localization Intracellular Transport Cell Projection Organization Transport Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Cilium Assembly Leptin-mediated Signaling Pathway Retina Homeostasis Cellular Pigmentation Cellular Protein Localization Cilium Organization Nervous System Development Negative Regulation Of Appetite Cytoplasmic Transport Signaling Cilium Morphogenesis Endomembrane System Organization Cellular Response To Leptin Stimulus Protein Localization To Cilium Cell Communication Cytoskeleton Organization Regulation Of Microtubule-based Movement Generation Of Neurons Regulation Of Cell Projection Organization Striatum Development Response To Leptin Signal Transduction Protein Localization To Organelle Neurogenesis Cell Projection Assembly Regulation Of Response To Food Developmental Process Regulation Of Appetite	Exocytosis Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Membrane Organization Secretion By Cell Intracellular Signal Transduction Secretion Ras Protein Signal Transduction Establishment Of Protein Localization Protein Localization Vesicle Docking Protein Transport Membrane Docking Rap Protein Signal Transduction Establishment Of Localization In Cell Cellular Localization Vesicle Docking Involved In Exocytosis Positive Regulation Of Protein Autophosphorylation Regulation Of Signaling Post-Golgi Vesicle-mediated Transport Transport Regulation Of Protein Autophosphorylation Organelle Organization Regulation Of Signal Transduction Golgi Vesicle Transport Exocyst Localization Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Platelet Activation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Signaling Cellular Protein Complex Localization Blood Coagulation Cell Communication Positive Regulation Of Ras GTPase Activity Hemostasis Positive Regulation Of Hydrolase Activity Positive Regulation Of Protein Phosphorylation Positive Regulation Of GTPase Activity Protein Complex Localization Cellular Response To Stimulus Regulation Of Cell Projection Organization Regulation Of GTPase Activity Regulation Of Ras GTPase Activity Positive Regulation Of Metabolic Process Positive Regulation Of Phosphorylation Regulation Of Body Fluid Levels Wound Healing Golgi To Plasma Membrane Transport
Tagcloud ?			adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto ralb recognition recognize regressions remarkable retrovirally termed
Tagcloud (Difference) ?			adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto ralb recognition recognize regressions remarkable retrovirally termed
Tagcloud (Intersection) ?