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CDC42 and PDE6D
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CDC42
PDE6D
Description
cell division cycle 42
phosphodiesterase 6D
Image
GO Annotations
Cellular Component
Golgi Membrane
Storage Vacuole
Cytoplasm
Endoplasmic Reticulum Membrane
Centrosome
Spindle
Cytosol
Cytoskeleton
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Membrane
Golgi Transport Complex
Filopodium
Dendrite
Midbody
Cell Leading Edge
Leading Edge Membrane
Protein-containing Complex
Cytoplasmic Ribonucleoprotein Granule
Cell Projection
Neuron Projection
Neuronal Cell Body
Apical Part Of Cell
Phagocytic Vesicle
Spindle Midzone
Extracellular Exosome
Cell Periphery
Mitotic Spindle
Postsynapse
Glutamatergic Synapse
Cytoplasm
Cytosol
Cytoskeleton
Cilium
Membrane
Cytoplasmic Vesicle Membrane
Cytoplasmic Vesicle
Cell Projection
Molecular Function
Nucleotide Binding
GTPase Activity
G Protein Activity
Protein Binding
GTP Binding
Hydrolase Activity
Protein Kinase Binding
GTP-dependent Protein Binding
Thioesterase Binding
GBD Domain Binding
Apolipoprotein A-I Receptor Binding
Identical Protein Binding
Ubiquitin Protein Ligase Activity
GTPase Inhibitor Activity
Protein Binding
Small GTPase Binding
Biological Process
Heart Process
Cardiac Conduction System Development
Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis
Endocytosis
Phagocytosis, Engulfment
Actin Filament Organization
Golgi Organization
Regulation Of Mitotic Nuclear Division
Nuclear Migration
Establishment Or Maintenance Of Cell Polarity
Signal Transduction
Integrin-mediated Signaling Pathway
Small GTPase-mediated Signal Transduction
Nervous System Development
Intracellular Protein Localization
Anatomical Structure Morphogenesis
Regulation Of Lamellipodium Assembly
Positive Regulation Of Lamellipodium Assembly
Substantia Nigra Development
Establishment Of Cell Polarity
Actin Cytoskeleton Organization
Cell Differentiation
Macrophage Differentiation
Positive Regulation Of Cell Growth
Positive Regulation Of Cell Migration
Positive Regulation Of Pseudopodium Assembly
Negative Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Cytokinesis
Regulation Of Actin Cytoskeleton Organization
Cell Junction Assembly
Adherens Junction Organization
Embryonic Heart Tube Development
Establishment Or Maintenance Of Apical/basal Cell Polarity
Dendritic Cell Migration
Neuropilin Signaling Pathway
Positive Regulation Of MAPK Cascade
Host-mediated Perturbation Of Viral Process
Establishment Of Epithelial Cell Apical/basal Polarity
Filopodium Assembly
Positive Regulation Of Pinocytosis
Neuron Fate Determination
Positive Regulation Of Cellular Component Organization
Regulation Of Filopodium Assembly
Positive Regulation Of Filopodium Assembly
Regulation Of Stress Fiber Assembly
Positive Regulation Of Stress Fiber Assembly
Nucleus Localization
Establishment Of Localization In Cell
Establishment Of Golgi Localization
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Heart Contraction
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Dendritic Spine Morphogenesis
Cellular Response To Type II Interferon
Organelle Transport Along Microtubule
Endothelin Receptor Signaling Pathway Involved In Heart Process
Regulation Of Postsynapse Organization
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Visual Perception
Sensory Perception Of Light Stimulus
Pathways
GPVI-mediated activation cascade
EGFR downregulation
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
CD28 dependent Vav1 pathway
EPHB-mediated forward signaling
EPHB-mediated forward signaling
DCC mediated attractive signaling
Inactivation of CDC42 and RAC1
VEGFA-VEGFR2 Pathway
Myogenesis
Myogenesis
RHO GTPases activate KTN1
RHO GTPases activate IQGAPs
RHO GTPases activate PAKs
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate Formins
RHO GTPases Activate Formins
MAPK6/MAPK4 signaling
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
G beta:gamma signalling through CDC42
CDC42 GTPase cycle
RAC1 GTPase cycle
RAC2 GTPase cycle
RHOQ GTPase cycle
RHOG GTPase cycle
RHOJ GTPase cycle
RHOU GTPase cycle
RAC3 GTPase cycle
RHOV GTPase cycle
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Factors involved in megakaryocyte development and platelet production
ARL13B-mediated ciliary trafficking of INPP5E
RAS processing
Drugs
Aminophosphonic acid-guanylate ester
Guanosine-5'-Diphosphate
Diseases
GWAS
Colorectal cancer (
25990418
)
Daytime sleep phenotypes (
27126917
)
Extremely high intelligence (
29520040
)
Gestational age at birth (maternal effect) (
28877031
)
Gynecologic disease (
31488892
)
Gynecologic disease (multivariate analysis) (
31488892
)
Hip circumference adjusted for BMI (
34021172
)
Immune response to smallpox vaccine (IL-6) (
22610502
)
Liver enzyme levels (alkaline phosphatase) (
33972514
)
Metabolite levels (
23823483
)
Uterine fibroids (
30194396
31249589
31488892
31649266
)
Uterine fibroids (MTAG) (
31488892
)
Eating disorders (purging via substances) (
23568457
)
Height (
18391951
)
Interacting Genes
383 interacting genes:
A2M
AARS1
ACADM
ACO1
ACO2
ACOT7
ACTR3
ADRM1
AGAP1
AGAP2
AHSG
AKR1B1
ALDH18A1
ANAPC13
ANXA11
ANXA2
AP3D1
APEX1
APOH
ARAP1
ARAP2
ARG1
ARHGAP1
ARHGAP10
ARHGAP11B
ARHGAP17
ARHGAP20
ARHGAP22
ARHGAP26
ARHGAP27
ARHGAP31
ARHGAP32
ARHGAP35
ARHGAP39
ARHGAP40
ARHGAP44
ARHGDIA
ARHGDIB
ARHGDIG
ARHGEF10
ARHGEF11
ARHGEF15
ARHGEF25
ARHGEF26
ARHGEF4
ARHGEF6
ARHGEF7
ARHGEF9
ARRB1
ARRB2
ATP5F1C
ATP5IF1
ATP5MF
ATP5PD
ATP6V1A
BAIAP2
BCAP31
BCCIP
BCL2L13
BCR
BIRC2
BLMH
BNIP2
BRD10
BTF3
BZW2
CALML5
CAPNS1
CAPZB
CARHSP1
CASP14
CASP3
CASP7
CBLL1
CBX3
CCN1
CDC42BPA
CDC42BPB
CDC42BPG
CDC42EP1
CDC42EP2
CDC42EP3
CDC42EP4
CDC42EP5
CDC42SE1
CDC5L
CDH1
CDKN2A
CEBPA
CFHR4
CGN
CMPK1
CNBP
CNOT1
COL1A1
COMT
COPA
COPE
COPG1
CPN1
CRIP2
CSE1L
CSN2
CSPG4
CTNNA1
DEF6
DEK
DHFR
DIAPH1
DIAPH2
DIAPH3
DNMBP
DOCK7
DOCK8
DOCK9
DPYSL2
DSG1
DSP
ECHS1
EDC4
EDF1
EEF1E1
EEF1G
EHD2
EHD4
EIF2AK2
EIF3D
EIF3F
EIF5
EIF5B
EPHA2
EPRS1
ERCC3
ERG28
ERICH6
ERRFI1
ETFA
FAM13B
FGD1
FGD2
FGD3
FGD4
FKBP10
FKBP1A
FKBP3
FLNA
FLNC
FMN2
FMNL2
FNBP1
FNBP1L
FNDC3B
FTH1
G6PD
GALNT2
GART
GDI1
GIT2
GLS
GMIP
GNB1
GRB2
GRWD1
GSR
GSTM5
H1-10
H1-5
H2BC13
HADH
HADHB
HDAC7
HDLBP
HERC2
HLA-G
HMGN1
HNRNPAB
HNRNPUL2
HSD17B10
HYOU1
IARS1
IGF2BP1
IPO5
IQGAP1
IQGAP2
ITSN1
JPT2
KARS1
KAT5
KHDRBS1
KPNA2
KTN1
KYNU
LARS1
LCK
LGALS1
LGALS7
LONP1
LRIF1
LRP2
LYZ
MAP2K3
MAP3K10
MAP3K11
MAP3K19
MAP3K4
MAP4
MAPRE1
MARCKSL1
MARK4
MASTL
MATR3
MCF2L
MCM3AP
MCM6
MCM7
MDH1
MDK
METAP2
MRM1
MRPL49
MSH2
MT-CO1
MTDH
MUC12
MYO1C
MYO6
MYO9A
NAA15
NASP
NCAPD2
NCF2
NEK6
NIBAN2
NOP2
NPLOC4
NQO1
NUDT21
NUP155
OCRL
OLA1
OPHN1
P3H1
PABPC4
PAK1
PAK2
PAK3
PAK4
PAK5
PAK6
PALLD
PARD3
PARD6A
PARD6B
PARD6G
PAXX
PCM1
PCNP
PDCD5
PDE6C
PDE6D
PGD
PGGT1B
PHAX
PHB2
PHPT1
PICALM
PIK3R1
PLD1
PLEKHG1
PLEKHG2
PLEKHG3
PLEKHG4
PLEKHG4B
PMS1
PPP2R1A
PRDX3
PREX2
PRKCA
PRKCG
PRKCI
PRKCZ
PSAT1
PSIP1
PSMB1
PSMC5
PSMC6
PSMD11
PSMD12
PSMD3
PSME3
PXDN
RAC2
RAP1GDS1
RARS1
RASGRF2
RBM8A
RHOJ
RIOK3
RO60
RPL22
RPL23
RPS15
RPS21
RPS6KB1
RRM1
S100A9
SDHA
SEPTIN2
SERPINB1
SERPINB2
SERPINB3
SF1
SF3A2
SH3BGRL3
SH3D19
SLC16A3
SMC2
SNCA
SNRNP70
SPATA13
SRGAP1
SRM
SRP72
SRSF1
SSB
SSX2IP
ST13
STARD8
STAT1
STAU1
STMN2
SYNE1
TBC1D3F
TBCA
TCEAL3
TIAM1
TMED10
TMED9
TMOD3
TMX1
TNFRSF10B
TNK2
TOR1AIP1
TP53
TPD52L2
TPM1
TRAF2
TRIM28
TRIM45
TRIM60
TRIO
TRIP10
TRRAP
TSFM
TTC12
TUBB3
TXNL1
TYMS
U2AF2
UBC
UBE2L3
UBR1
UGDH
UNC119
USP6
VARS1
VASP
VAV1
VRK2
WAS
WASF1
WASF2
WASL
WIPF1
XIAP
XPO1
YARS1
YWHAH
ZNF175
ZNF234
ZNF415
ZNF420
ZNF622
25 interacting genes:
ARL15
ARL16
ARL2
ARL3
CDC42
CETN3
FAM219A
GNAI1
GRK1
GRK7
HRAS
OTP
PTGIR
RAB13
RAB18
RAB8A
RAD23A
RAP1A
RAP2B
RASA1
RHEB
RHOA
RHOB
RND1
RPGR
Entrez ID
998
5147
HPRD ID
00309
04056
Ensembl ID
ENSG00000070831
ENSG00000156973
Uniprot IDs
P60953
B8ZZK5
O43924
Q6IB24
PDB IDs
1A4R
1AJE
1AM4
1AN0
1CEE
1CF4
1DOA
1E0A
1EES
1GRN
1GZS
1KI1
1KZ7
1KZG
1NF3
2ASE
2DFK
2KB0
2NGR
2ODB
2QRZ
2WM9
2WMN
2WMO
3GCG
3QBV
3VHL
4DID
4ITR
4JS0
4YC7
4YDH
5CJP
5FI1
5HZK
5UPK
5UPL
6AJ4
6AJL
6SIU
6SUP
6TKY
6TKZ
7S0Y
8I5F
1KSG
1KSH
1KSJ
3T5G
3T5I
4JHP
4JV6
4JV8
4JVB
4JVF
5E80
5E8F
5F2U
5ML2
5ML3
5ML4
5ML6
5ML8
5NAL
5TAR
5TB5
5X72
5X73
5X74
5YAV
5YAW
7PAC
7PAD
7PAE
7Q9Q
7Q9R
7Q9S
7Q9U
7QF9
7QJK
Enriched GO Terms of Interacting Partners
?
Cytosol
Cytoplasm
Regulation Of Small GTPase Mediated Signal Transduction
GTPase Activator Activity
Regulation Of Intracellular Signal Transduction
Small GTPase Binding
Guanyl-nucleotide Exchange Factor Activity
Actin Filament-based Process
Small GTPase-mediated Signal Transduction
Actin Cytoskeleton Organization
Intracellular Signaling Cassette
Lamellipodium
Intracellular Signal Transduction
Regulation Of Signal Transduction
Cytoskeleton Organization
RNA Binding
Regulation Of Signaling
Regulation Of Cell Communication
Rho Protein Signal Transduction
Extracellular Exosome
Organelle Organization
Cadherin Binding
Cell-cell Junction
Regulation Of Actin Cytoskeleton Organization
Cell Projection Organization
Cell Cortex
PAR Polarity Complex
Biological_process
Regulation Of Actin Filament-based Process
Ruffle
Actin Filament Organization
Regulation Of Cytoskeleton Organization
Regulation Of Cell Shape
Regulation Of Cellular Component Organization
Protein Serine Kinase Activity
Supramolecular Fiber Organization
Anchoring Junction
Regulation Of Protein Metabolic Process
Actin Cytoskeleton
Cellular Component Assembly
Regulation Of Programmed Cell Death
Regulation Of Actin Filament Organization
Actin Binding
Cytoskeleton
Positive Regulation Of Cellular Component Organization
Regulation Of Supramolecular Fiber Organization
Regulation Of Cell Morphogenesis
Actin Filament
Protein Serine/threonine Kinase Activity
Regulation Of Rho Protein Signal Transduction
GTPase Activity
GTP Binding
GDP Binding
Nucleotide Binding
Small GTPase-mediated Signal Transduction
G Protein Activity
Intracellular Signaling Cassette
Ciliary Basal Body
Intracellular Signal Transduction
Mitotic Cytokinesis
Midbody
Rhodopsin Kinase Activity
Regulation Of Cytoskeleton Organization
Cytoskeleton-dependent Cytokinesis
Centrosome
Photoreceptor Connecting Cilium
Hydrolase Activity
Signal Transduction
G Protein-coupled Receptor Kinase Activity
Cellular Developmental Process
Golgi Apparatus
Extracellular Exosome
Rap Protein Signal Transduction
Regulation Of Opsin-mediated Signaling Pathway
Protein Localization To Cilium
Cell-cell Junction Organization
Cytoskeleton
Regulation Of Actin Cytoskeleton Organization
Endothelial Tube Morphogenesis
Regulation Of Actin Filament-based Process
Regulation Of Modification Of Postsynaptic Structure
Cellular Response To Forskolin
Phagocytic Vesicle
Regulation Of Cell-substrate Adhesion
Establishment Of Epithelial Cell Apical/basal Polarity
Response To Forskolin
Trans-Golgi Network Transport Vesicle
Protein Localization To Cell Periphery
Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane
Regulation Of Modification Of Synaptic Structure
Recycling Endosome Membrane
Photoreceptor Disc Membrane
Protein Kinase Binding
Establishment Of Apical/basal Cell Polarity
G-protein Beta/gamma-subunit Complex Binding
Polarized Epithelial Cell Differentiation
Establishment Of Monopolar Cell Polarity
Actin Filament Organization
Cell Junction Assembly
Establishment Or Maintenance Of Monopolar Cell Polarity
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Tagcloud (Difference)
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Tagcloud (Intersection)
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