SNX6

Gene Name		sorting nexin 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Cytoplasm Cytoplasmic Membrane-bounded Vesicle Extrinsic Component Of Membrane Retromer Complex Early Endosome Membrane Tubular Endosome
	Molecular Function	Protein Binding Dynactin Binding Phosphatidylinositol Binding Protein Homodimerization Activity
	Biological Process	Intracellular Protein Transport Endocytosis Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Vesicle Organization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Retrograde Transport, Endosome To Golgi Negative Regulation Of Transcription, DNA-templated Regulation Of Histamine Secretion By Mast Cell
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		22 interactors: ACVR2B ACVRL1 BMPR1B BRCA1 BRMS1 CALM1 COIL CSNK2A2 DISC1 EGFR INSR LEPR NDEL1 PDGFRA PIM1 SNX1 SNX2 SNX4 TGFBR1 TGFBR2 TNIK TPT1
Entrez ID		58533
HPRD ID		12086
Ensembl ID		ENSG00000129515
Uniprot IDs		B4DJS7 Q9UNH7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Signal Transduction By Phosphorylation Regulation Of Signaling Developmental Process Positive Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Regulation Of Signal Transduction Positive Regulation Of Transferase Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Protein Phosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Protein Phosphorylation Positive Regulation Of Metabolic Process Anatomical Structure Development Phosphorylation Intracellular Signal Transduction Regulation Of Kinase Activity Positive Regulation Of Cellular Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Multicellular Organismal Development Regulation Of Phosphorylation Activation Of Protein Kinase Activity Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Anatomical Structure Morphogenesis Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Cell Surface Receptor Signaling Pathway Regulation Of Cell Differentiation Cellular Protein Modification Process Cellular Response To Growth Factor Stimulus Regulation Of Metabolic Process Sensory Organ Development Camera-type Eye Development Response To Growth Factor Positive Regulation Of Signal Transduction Retina Vasculature Development In Camera-type Eye Eye Development Phosphate-containing Compound Metabolic Process Protein Autophosphorylation Regulation Of Catalytic Activity Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cell Proliferation Palate Development Activin Receptor Signaling Pathway Chordate Embryonic Development Embryo Development
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