PDZRN3 and LNX2

Number of citations of the paper that reports this interaction (PMID 22889411)
1

Data Source:
BioGRID (two hybrid)

		PDZRN3	LNX2
Gene Name		PDZ domain containing ring finger 3	ligand of numb-protein X 2
Image
Gene Ontology Annotations	Cellular Component	Neuromuscular Junction
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity	Protein Binding Zinc Ion Binding PDZ Domain Binding
	Biological Process	Neuromuscular Junction Development Protein Ubiquitination	Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Dialysis-related mortality ( 21546767)	Large B-cell lymphoma ( 21471979)
Protein-Protein Interactions		5 interactors: BMPR2 EFNB2 LNX1 LNX2 UBE2D2	17 interactors: CBX4 CXADR HOXA1 IGSF5 LNX1 MDGA1 NUMB PDZRN3 PDZRN4 PKDREJ RLIM RNF138 SHISA2 UBE2I UBE2T UBE2Z USP2
Entrez ID		23024	222484
HPRD ID		15115	10042
Ensembl ID		ENSG00000121440	ENSG00000139517
Uniprot IDs		B7ZAG0 F5H8I9 Q9UPQ7	Q8N448
PDB IDs		1UHP 1WH1	2VWR
Enriched GO Terms of Interacting Partners?		Lymph Vessel Development Regulation Of Chemotaxis Regulation Of Lung Blood Pressure Negative Regulation Of Chondrocyte Proliferation Negative Regulation Of Vasoconstriction Regulation Of Behavior Protein Homooligomerization Regulation Of Epithelial Cell Proliferation Positive Regulation Of Axon Extension Involved In Axon Guidance Lymphatic Endothelial Cell Differentiation	Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Protein Sumoylation Cellular Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Optokinetic Behavior Abducens Nerve Formation Random Inactivation Of X Chromosome Positive Regulation Of SUMO Transferase Activity Protein Catabolic Process Facial Nucleus Development Positive Regulation Of Polarized Epithelial Cell Differentiation Protein Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Rhombomere 4 Development Semicircular Canal Formation Cellular Macromolecule Catabolic Process Rhombomere 3 Development Rhombomere 5 Development Neuroblast Division In Subventricular Zone Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination AV Node Cell To Bundle Of His Cell Communication
Tagcloud ?			amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt
Tagcloud (Difference) ?			amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt
Tagcloud (Intersection) ?