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KDM2A and ZNF512B
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
BioGRID
(two hybrid)
KDM2A
ZNF512B
Gene Name
lysine (K)-specific demethylase 2A
zinc finger protein 512B
Image
Gene Ontology Annotations
Cellular Component
Nuclear Chromatin
Nucleus
Nucleoplasm
Nucleolus
Nucleus
Molecular Function
Zinc Ion Binding
Unmethylated CpG Binding
Histone Demethylase Activity (H3-K36 Specific)
DNA Binding
Metal Ion Binding
Biological Process
Double-strand Break Repair Via Nonhomologous End Joining
Chromatin Organization
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Oxidation-reduction Process
Histone H3-K36 Demethylation
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Pathways
Chromatin modifying enzymes
Chromatin organization
HDMs demethylate histones
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Protein-Protein Interactions
9 interactors:
FOS
HIST2H3C
HIST3H3
RELA
SMAD3
SMAD7
UBC
UBE2G2
ZNF512B
60 interactors:
ANKLE2
ANKRD28
AP1G1
APLP2
ATRX
BRD1
BTBD2
CDC123
CREBZF
CTBP2
DCTN1
DDX3X
DROSHA
DVL3
EHMT2
FAM129B
FHL3
GLRX3
HEYL
HTATSF1
IL36RN
INVS
KDM2A
KDM3B
KLF10
KMT2B
L1TD1
LAMB2
LZTS2
MBD1
MYH10
OS9
PAPPA2
PBRM1
PDE4DIP
PEG10
PIAS4
PLCG2
PPP1R15A
PTPRF
RPS27A
SDF4
SIAH1
SMAD1
SPTBN1
SUPT5H
TGM2
TNKS2
TOM1
TOX4
TRAF1
TRAF4
VHL
VPS35
VPS41
VWF
XPC
XRCC6
YES1
ZMYM2
Entrez ID
22992
57473
HPRD ID
05741
13840
Ensembl ID
ENSG00000173120
ENSG00000196700
Uniprot IDs
I3VM53
Q9Y2K7
Q96KM6
PDB IDs
2YU1
2YU2
4BBQ
2GQJ
Enriched GO Terms of Interacting Partners
?
Transforming Growth Factor Beta Receptor Signaling Pathway
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Toll-like Receptor Signaling Pathway
Regulation Of Protein Catabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Activation Of Innate Immune Response
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Chondrocyte Differentiation
Regulation Of Cellular Response To Growth Factor Stimulus
Positive Regulation Of Innate Immune Response
Gene Expression
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Gene Expression
Regulation Of Gene Expression, Epigenetic
Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Process
Negative Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Organ Development
System Development
Transcription, DNA-templated
Developmental Process
Chromosome Organization
Anatomical Structure Development
Regulation Of Gene Expression
RNA Biosynthetic Process
Response To Stimulus
Negative Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression, Epigenetic
Chromatin Modification
Negative Regulation Of Biosynthetic Process
Cell Cycle
Cellular Response To Stimulus
Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cell Cycle Process
Multicellular Organismal Development
Viral Genome Replication
Positive Regulation Of Macromolecule Biosynthetic Process
Chromatin Organization
Wnt Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Cell Surface Receptor Signaling Pathway
Organelle Organization
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Metabolic Process
Chromatin Remodeling
RNA Metabolic Process
Primary MiRNA Processing
Vesicle-mediated Transport
Endosomal Transport
Regulation Of Signal Transduction
Cellular Response To Stress
Mitotic Cell Cycle Process
Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Gene Expression
Response To Stress
Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud
?
al
architecture
box
cip1
demethylase
demethylases
di
e10
elucidate
embryogenesis
embryonic
et
fbxl10
fbxl11
fukuda
h2a
h3k36
ishimura
jmjd5
knockout
ko
lethality
leucine
mono
pcg
pivotal
polycomb
removes
ubiquitination
Tagcloud (Difference)
?
al
architecture
box
cip1
demethylase
demethylases
di
e10
elucidate
embryogenesis
embryonic
et
fbxl10
fbxl11
fukuda
h2a
h3k36
ishimura
jmjd5
knockout
ko
lethality
leucine
mono
pcg
pivotal
polycomb
removes
ubiquitination
Tagcloud (Intersection)
?