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MAST1 and FBXL12
Number of citations of the paper that reports this interaction (PMID
21163940
)
13
Data Source:
BioGRID
(two hybrid)
MAST1
FBXL12
Gene Name
microtubule associated serine/threonine kinase 1
F-box and leucine-rich repeat protein 12
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytoskeleton
Plasma Membrane
Ubiquitin Ligase Complex
Cytoplasm
Molecular Function
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Protein Binding
Biological Process
Protein Phosphorylation
Cytoskeleton Organization
Intracellular Signal Transduction
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
37 interactors:
A2M
AP1M2
APOE
APP
BLMH
CDK5
CYP2C8
CYP2C9
DNAJB1
ECSIT
EGFR
ELAVL3
EXOC6
EXOSC1
FBXL12
FBXW4
GCDH
IFIT3
IFIT5
LONP1
LOXL4
MGEA5
NOS3
PAXIP1
PRAM1
PRDX2
PSEN2
PTEN
RAB3A
RAB3D
RAD23A
RNF32
RNLS
RPP30
SNTA1
SNTB2
STAMBPL1
14 interactors:
A2M
APOE
CDC37
CDKN1C
DOCK8
ECSIT
FXYD3
LNX1
MAST1
PSEN1
PSEN2
RNF32
SMAD1
TGFBR1
Entrez ID
22983
54850
HPRD ID
17469
12363
Ensembl ID
ENSG00000105613
ENSG00000127452
Uniprot IDs
Q9Y2H9
Q9NXK8
PDB IDs
2M9X
3PS4
Enriched GO Terms of Interacting Partners
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Catabolic Process
Synapse Organization
Negative Regulation Of Protein Metabolic Process
Response To Stress
Negative Regulation Of Cellular Protein Metabolic Process
Response To Abiotic Stimulus
Negative Regulation Of Presynaptic Membrane Organization
Regulation Of Synaptic Plasticity
Regulation Of Synaptic Transmission
Regulation Of Oxidoreductase Activity
Synapse Assembly
Exocytosis
Regulation Of Cellular Protein Metabolic Process
Axon Development
Response To Stimulus
Regulation Of Presynaptic Membrane Organization
Regulation Of Nitric-oxide Synthase Activity
Regulation Of Protein Metabolic Process
Negative Regulation Of Dendritic Spine Development
Learning Or Memory
Regulation Of Proteolysis
Regulation Of Dendritic Spine Development
Negative Regulation Of Cell Death
Cognition
Omega-hydroxylase P450 Pathway
Synaptic Vesicle Exocytosis
Anatomical Structure Morphogenesis
Secretion By Cell
Vesicle Docking Involved In Exocytosis
Axonogenesis
Positive Regulation Of Exocytosis
Neuron Projection Development
Vesicle-mediated Transport
Glial Cell Differentiation
Protein Metabolic Process
Establishment Of Protein Localization
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cell Morphogenesis Involved In Neuron Differentiation
Negative Regulation Of Neuron Differentiation
Membrane Organization
Oxidative Demethylation
Protein Catabolic Process
Establishment Of Vesicle Localization
Oligodendrocyte Differentiation
Positive Regulation Of Catalytic Activity
Regulation Of ERBB Signaling Pathway
Vesicle Docking
Regulation Of Cellular Amino Acid Metabolic Process
Endothelial Cell Migration
Vesicle Localization
Regulation Of Catalytic Activity
Embryonic Morphogenesis
Intracellular Signal Transduction
Regulation Of Protein Kinase Activity
Regulation Of Kinase Activity
Thymus Development
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Cell Death
Generation Of Neurons
Amyloid Precursor Protein Catabolic Process
Anatomical Structure Morphogenesis
Neurogenesis
Regulation Of Protein Phosphorylation
Cell Fate Commitment
Neuron Differentiation
Embryo Development
Negative Regulation Of Protein Phosphorylation
Cell Activation
Response To Wounding
Regulation Of Cellular Protein Metabolic Process
Regulation Of Phosphorylation
Beta-amyloid Metabolic Process
Amyloid Precursor Protein Metabolic Process
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Phosphorylation
Membrane Protein Ectodomain Proteolysis
Notch Receptor Processing
Response To Cholesterol
Regulation Of Protein Binding
Regulation Of Protein Metabolic Process
Regulation Of Apoptotic Process
Regulation Of Phosphorus Metabolic Process
Negative Regulation Of Protein Metabolic Process
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Nervous System Development
Regulation Of Cell Death
Regulation Of Synaptic Plasticity
Regulation Of Cell Morphogenesis
Pattern Specification Process
Regulation Of Cell Projection Organization
Neuron Development
Gland Development
Cell Differentiation
Endoplasmic Reticulum Calcium Ion Homeostasis
Regulation Of Metabolic Process
Response To Stress
Dorsal/ventral Neural Tube Patterning
Negative Regulation Of Endothelial Cell Proliferation
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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