FBXL12 and MARCHF2

		FBXL12	MARCHF2
Description		F-box and leucine rich repeat protein 12	membrane associated ring-CH-type finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Cytosol	Golgi Membrane Cytoplasm Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination	Endocytosis Protein Ubiquitination Suppression Of Viral Release By Host Antibacterial Innate Immune Response Antiviral Innate Immune Response Positive Regulation Of Lysosomal Protein Catabolic Process
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Pursuit maintenance gain ( 29064472)
Interacting Genes		19 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FBF1 FXYD3 GEMIN4 LNX1 MAST1 PSEN1 PSEN2 PSME3 RNF32 SMAD1 TGFBR1 UBE2D3	34 interacting genes: AQP6 CCL4 CD79A CDC34 CFTR CREB3L1 ERGIC3 F11R FAM209A FATE1 GJA8 GPX8 IKBKG KASH5 LDLRAD1 LGR4 MUC1 PEX12 PLPPR2 SCN3B SLC18A1 SSMEM1 STX6 SYNE4 TMEM106C TMEM179B TMEM52B TMEM86B TSPAN12 TSPO2 UBC UBE2D1 UBE2E1 UBE2H
Entrez ID		54850	51257
HPRD ID		12363	14361
Ensembl ID		ENSG00000127452	ENSG00000099785
Uniprot IDs		Q9NXK8	Q9P0N8
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid Precursor Protein Metabolic Process Positive Regulation Of Amyloid Fibril Formation Aspartic Endopeptidase Activity, Intramembrane Cleaving Gamma-secretase Complex Notch Receptor Processing Amyloid-beta Formation Regulation Of Amyloid Fibril Formation I-SMAD Binding Amyloid Precursor Protein Catabolic Process	Ubiquitin Conjugating Enzyme Activity Membrane Protein Binding Protein K48-linked Ubiquitination Ubiquitin-protein Transferase Activity Modification-dependent Protein Catabolic Process Meiotic Nuclear Membrane Microtubule Tethering Complex Protein Ubiquitination Endoplasmic Reticulum Membrane Protein Polyubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?