FBXL12 and ZNF44

		FBXL12	ZNF44
Description		F-box and leucine rich repeat protein 12	zinc finger protein 44
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Cytosol	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Pursuit maintenance gain ( 29064472)
Interacting Genes		19 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FBF1 FXYD3 GEMIN4 LNX1 MAST1 PSEN1 PSEN2 PSME3 RNF32 SMAD1 TGFBR1 UBE2D3	4 interacting genes: CSNK2B HGS TLX3 UPF2
Entrez ID		54850	51710
HPRD ID		12363	01927
Ensembl ID		ENSG00000127452	ENSG00000197857
Uniprot IDs		Q9NXK8	F8W7T7 P15621
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid Precursor Protein Metabolic Process Positive Regulation Of Amyloid Fibril Formation Aspartic Endopeptidase Activity, Intramembrane Cleaving Gamma-secretase Complex Notch Receptor Processing Amyloid-beta Formation Regulation Of Amyloid Fibril Formation I-SMAD Binding Amyloid Precursor Protein Catabolic Process
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