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FBXL12
Gene Name
F-box and leucine-rich repeat protein 12
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ubiquitin Ligase Complex
Cytoplasm
Molecular Function
Protein Binding
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
14 interactors:
A2M
APOE
CDC37
CDKN1C
DOCK8
ECSIT
FXYD3
LNX1
MAST1
PSEN1
PSEN2
RNF32
SMAD1
TGFBR1
Entrez ID
54850
HPRD ID
12363
Ensembl ID
ENSG00000127452
Uniprot IDs
Q9NXK8
PDB IDs
Enriched GO Terms of Interacting Partners
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Regulation Of Catalytic Activity
Embryonic Morphogenesis
Intracellular Signal Transduction
Regulation Of Protein Kinase Activity
Regulation Of Kinase Activity
Thymus Development
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Cell Death
Generation Of Neurons
Amyloid Precursor Protein Catabolic Process
Anatomical Structure Morphogenesis
Neurogenesis
Regulation Of Protein Phosphorylation
Cell Fate Commitment
Neuron Differentiation
Embryo Development
Negative Regulation Of Protein Phosphorylation
Cell Activation
Response To Wounding
Regulation Of Cellular Protein Metabolic Process
Regulation Of Phosphorylation
Beta-amyloid Metabolic Process
Amyloid Precursor Protein Metabolic Process
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Phosphorylation
Membrane Protein Ectodomain Proteolysis
Notch Receptor Processing
Response To Cholesterol
Regulation Of Protein Binding
Regulation Of Protein Metabolic Process
Regulation Of Apoptotic Process
Regulation Of Phosphorus Metabolic Process
Negative Regulation Of Protein Metabolic Process
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Nervous System Development
Regulation Of Cell Death
Regulation Of Synaptic Plasticity
Regulation Of Cell Morphogenesis
Pattern Specification Process
Regulation Of Cell Projection Organization
Neuron Development
Gland Development
Cell Differentiation
Endoplasmic Reticulum Calcium Ion Homeostasis
Regulation Of Metabolic Process
Response To Stress
Dorsal/ventral Neural Tube Patterning
Negative Regulation Of Endothelial Cell Proliferation
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