FBXL12

Name	F-box and leucine rich repeat protein 12
Structure	No pdb structure
Novel Interactors	5 novel interactors: MARCHF2 SHFL ZNF44 ZNF562 ZNF823
Interactors	19 interactors: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FBF1 FXYD3 GEMIN4 LNX1 MAST1 PSEN1 PSEN2 PSME3 RNF32 SMAD1 TGFBR1 UBE2D3
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Cytosol
	Molecular Function	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination
Pathways	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
GWAS	Pursuit maintenance gain ( 29064472 )
Entrez ID	54850
HPRD ID	12363
Ensembl ID	ENSG00000127452
Uniprot IDs	Q9NXK8
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Amyloid Precursor Protein Metabolic Process Positive Regulation Of Amyloid Fibril Formation Aspartic Endopeptidase Activity, Intramembrane Cleaving Gamma-secretase Complex Notch Receptor Processing Amyloid-beta Formation Regulation Of Amyloid Fibril Formation I-SMAD Binding Amyloid Precursor Protein Catabolic Process