MAST1 and RAB3A

Number of citations of the paper that reports this interaction (PMID 21163940)
13

Data Source:
BioGRID (two hybrid)

		MAST1	RAB3A
Gene Name		microtubule associated serine/threonine kinase 1	RAB3A, member RAS oncogene family
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane	Acrosomal Vesicle Endosome Cytosol Plasma Membrane Synaptic Vesicle Axon Secretory Granule Membrane Vesicle Terminal Bouton Protein Complex Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Clathrin-sculpted Glutamate Transport Vesicle Membrane Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	ATPase Activator Activity GTPase Activity Protein Binding GTP Binding Protein C-terminus Binding GDP Binding Myosin V Binding GTPase Binding ATPase Binding
	Biological Process	Protein Phosphorylation Cytoskeleton Organization Intracellular Signal Transduction	Respiratory System Process Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Mitochondrion Organization Synaptic Transmission Neurotransmitter Secretion Neuromuscular Synaptic Transmission Axonogenesis Protein Secretion Post-embryonic Development Glutamate Secretion Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Lung Development Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Rab Protein Signal Transduction Positive Regulation Of ATPase Activity Synaptic Vesicle Recycling Constitutive Secretory Pathway Positive Regulation Of Exocytosis Regulation Of Short-term Neuronal Synaptic Plasticity Maintenance Of Presynaptic Active Zone Structure Sensory Perception Of Touch Response To Electrical Stimulus Protein Localization To Plasma Membrane Positive Regulation Of Regulated Secretory Pathway
Pathways			Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		37 interactors: A2M AP1M2 APOE APP BLMH CDK5 CYP2C8 CYP2C9 DNAJB1 ECSIT EGFR ELAVL3 EXOC6 EXOSC1 FBXL12 FBXW4 GCDH IFIT3 IFIT5 LONP1 LOXL4 MGEA5 NOS3 PAXIP1 PRAM1 PRDX2 PSEN2 PTEN RAB3A RAB3D RAD23A RNF32 RNLS RPP30 SNTA1 SNTB2 STAMBPL1	24 interactors: A2M ADRB2 AP1M2 APP CASK CHM CHML DMXL2 ECSIT EGFR MAST1 PSEN1 RAB3IL1 RAB3IP RABAC1 RABGGTB RABIF RIMS1 RIMS2 RNF32 RPH3A RPH3AL SYTL4 SYTL5
Entrez ID		22983	5864
HPRD ID		17469	01535
Ensembl ID		ENSG00000105613	ENSG00000105649
Uniprot IDs		Q9Y2H9	P20336
PDB IDs		2M9X 3PS4
Enriched GO Terms of Interacting Partners?		Catabolic Process Synapse Organization Negative Regulation Of Protein Metabolic Process Response To Stress Negative Regulation Of Cellular Protein Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Presynaptic Membrane Organization Regulation Of Synaptic Plasticity Regulation Of Synaptic Transmission Regulation Of Oxidoreductase Activity Synapse Assembly Exocytosis Regulation Of Cellular Protein Metabolic Process Axon Development Response To Stimulus Regulation Of Presynaptic Membrane Organization Regulation Of Nitric-oxide Synthase Activity Regulation Of Protein Metabolic Process Negative Regulation Of Dendritic Spine Development Learning Or Memory Regulation Of Proteolysis Regulation Of Dendritic Spine Development Negative Regulation Of Cell Death Cognition Omega-hydroxylase P450 Pathway Synaptic Vesicle Exocytosis Anatomical Structure Morphogenesis Secretion By Cell Vesicle Docking Involved In Exocytosis Axonogenesis Positive Regulation Of Exocytosis Neuron Projection Development Vesicle-mediated Transport Glial Cell Differentiation Protein Metabolic Process Establishment Of Protein Localization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Morphogenesis Involved In Neuron Differentiation Negative Regulation Of Neuron Differentiation Membrane Organization Oxidative Demethylation Protein Catabolic Process Establishment Of Vesicle Localization Oligodendrocyte Differentiation Positive Regulation Of Catalytic Activity Regulation Of ERBB Signaling Pathway Vesicle Docking Regulation Of Cellular Amino Acid Metabolic Process Endothelial Cell Migration Vesicle Localization	Establishment Of Protein Localization Protein Localization Cellular Localization Establishment Of Localization In Cell Protein Transport Intracellular Transport Cellular Protein Localization Exocytosis Intracellular Protein Transport Secretion Secretion By Cell Transport Vesicle-mediated Transport Protein Geranylgeranylation Regulation Of Catalytic Activity Protein Prenylation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Positive Regulation Of Hydrolase Activity Calcium Ion-dependent Exocytosis Of Neurotransmitter Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Inhibitory Postsynaptic Membrane Potential Membrane Organization Neurotransmitter Secretion Regulation Of Signaling Establishment Of Organelle Localization Regulation Of Neurotransmitter Levels Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Protein Binding Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Exocytosis Positive Regulation Of GTPase Activity Neurological System Process Endoplasmic Reticulum Calcium Ion Homeostasis Neurotransmitter Transport Positive Regulation Of Excitatory Postsynaptic Membrane Potential Organelle Localization Visual Perception Membrane Hyperpolarization Regulation Of GTPase Activity Sensory Perception Of Light Stimulus Vesicle Targeting Positive Regulation Of Membrane Potential Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Vesicle Localization Regulation Of Vasodilation
Tagcloud ?			abundant adenohypophyseal anterior att cellubrevin corticotroph endocrine exocytosis fractionation fractions granules immunoblotting immunocytochemical isoform location microvesicles organelles pituitary represented secretory snap subcellular synaptic synaptobrevin synaptophysin synaptotagmin syntaxin took vesicles
Tagcloud (Difference) ?			abundant adenohypophyseal anterior att cellubrevin corticotroph endocrine exocytosis fractionation fractions granules immunoblotting immunocytochemical isoform location microvesicles organelles pituitary represented secretory snap subcellular synaptic synaptobrevin synaptophysin synaptotagmin syntaxin took vesicles
Tagcloud (Intersection) ?