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MAST1 and AP1M2
Number of citations of the paper that reports this interaction (PMID
21163940
)
13
Data Source:
BioGRID
(two hybrid)
MAST1
AP1M2
Gene Name
microtubule associated serine/threonine kinase 1
adaptor-related protein complex 1, mu 2 subunit
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytoskeleton
Plasma Membrane
Golgi Membrane
Lysosomal Membrane
Cytosol
Clathrin Adaptor Complex
Cytoplasmic Vesicle Membrane
Clathrin-coated Vesicle Membrane
Trans-Golgi Network Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Biological Process
Protein Phosphorylation
Cytoskeleton Organization
Intracellular Signal Transduction
Protein Targeting
Post-Golgi Vesicle-mediated Transport
Vesicle Targeting
Viral Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Regulation Of Defense Response To Virus By Virus
Membrane Organization
Pathways
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
HIV Infection
Host Interactions of HIV factors
Golgi Associated Vesicle Biogenesis
The role of Nef in HIV-1 replication and disease pathogenesis
Nef mediated downregulation of MHC class I complex cell surface expression
Clathrin derived vesicle budding
Lysosome Vesicle Biogenesis
MHC class II antigen presentation
trans-Golgi Network Vesicle Budding
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
37 interactors:
A2M
AP1M2
APOE
APP
BLMH
CDK5
CYP2C8
CYP2C9
DNAJB1
ECSIT
EGFR
ELAVL3
EXOC6
EXOSC1
FBXL12
FBXW4
GCDH
IFIT3
IFIT5
LONP1
LOXL4
MGEA5
NOS3
PAXIP1
PRAM1
PRDX2
PSEN2
PTEN
RAB3A
RAB3D
RAD23A
RNF32
RNLS
RPP30
SNTA1
SNTB2
STAMBPL1
20 interactors:
A2M
AP1B1
AP1G1
AP1M1
AP1S1
AP2B1
APP
BLMH
ECSIT
EHD2
GAK
LDLR
LOXL4
MAST1
NDRG1
PSEN1
PVR
RAB3A
RAB3D
TGOLN2
Entrez ID
22983
10053
HPRD ID
17469
06296
Ensembl ID
ENSG00000105613
ENSG00000129354
Uniprot IDs
Q9Y2H9
Q9Y6Q5
PDB IDs
2M9X
3PS4
Enriched GO Terms of Interacting Partners
?
Catabolic Process
Synapse Organization
Negative Regulation Of Protein Metabolic Process
Response To Stress
Negative Regulation Of Cellular Protein Metabolic Process
Response To Abiotic Stimulus
Negative Regulation Of Presynaptic Membrane Organization
Regulation Of Synaptic Plasticity
Regulation Of Synaptic Transmission
Regulation Of Oxidoreductase Activity
Synapse Assembly
Exocytosis
Regulation Of Cellular Protein Metabolic Process
Axon Development
Response To Stimulus
Regulation Of Presynaptic Membrane Organization
Regulation Of Nitric-oxide Synthase Activity
Regulation Of Protein Metabolic Process
Negative Regulation Of Dendritic Spine Development
Learning Or Memory
Regulation Of Proteolysis
Regulation Of Dendritic Spine Development
Negative Regulation Of Cell Death
Cognition
Omega-hydroxylase P450 Pathway
Synaptic Vesicle Exocytosis
Anatomical Structure Morphogenesis
Secretion By Cell
Vesicle Docking Involved In Exocytosis
Axonogenesis
Positive Regulation Of Exocytosis
Neuron Projection Development
Vesicle-mediated Transport
Glial Cell Differentiation
Protein Metabolic Process
Establishment Of Protein Localization
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cell Morphogenesis Involved In Neuron Differentiation
Negative Regulation Of Neuron Differentiation
Membrane Organization
Oxidative Demethylation
Protein Catabolic Process
Establishment Of Vesicle Localization
Oligodendrocyte Differentiation
Positive Regulation Of Catalytic Activity
Regulation Of ERBB Signaling Pathway
Vesicle Docking
Regulation Of Cellular Amino Acid Metabolic Process
Endothelial Cell Migration
Vesicle Localization
Vesicle-mediated Transport
Regulation Of Defense Response To Virus By Virus
Establishment Of Localization In Cell
Regulation Of Defense Response To Virus
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Endocytosis
Antigen Processing And Presentation Of Peptide Antigen
Cellular Localization
Intracellular Transport
Antigen Processing And Presentation
Viral Process
Intracellular Protein Transport
Cellular Protein Localization
Protein Transport
Protein Localization
Positive Regulation Of Regulated Secretory Pathway
Establishment Of Protein Localization
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Post-Golgi Vesicle-mediated Transport
Transport
Immune System Process
Regulation Of Immune System Process
Response To External Stimulus
Regulation Of Regulated Secretory Pathway
Exocytosis
Receptor-mediated Endocytosis
Synaptic Vesicle Exocytosis
Response To Stimulus
Positive Regulation Of Exocytosis
Endosome To Melanosome Transport
Pigment Granule Maturation
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cellular Pigment Accumulation
Regulation Of ERBB Signaling Pathway
Membrane Organization
Secretion By Cell
Golgi Vesicle Transport
Neurotransmitter Secretion
Synaptic Vesicle Transport
Cell Differentiation
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Establishment Of Organelle Localization
Secretion
Positive Regulation Of Natural Killer Cell Mediated Immunity
Melanosome Organization
Pigment Granule Organization
Regulation Of Natural Killer Cell Mediated Cytotoxicity
Regulation Of Neurotransmitter Levels
Tagcloud
?
acaa1
analogous
aspirates
cgn
combat
dcn
ddr1
deadly
ec
ecs
efemp2
endometrial
eps8l2
fastkd1
gmip
ikbke
minimally
noncarcinoma
p2rx4
p4hb
phkg2
ppfibp2
ppp1r16a
rassf7
rnf183
sirt6
socs2
tjp3
uterine
Tagcloud (Difference)
?
acaa1
analogous
aspirates
cgn
combat
dcn
ddr1
deadly
ec
ecs
efemp2
endometrial
eps8l2
fastkd1
gmip
ikbke
minimally
noncarcinoma
p2rx4
p4hb
phkg2
ppfibp2
ppp1r16a
rassf7
rnf183
sirt6
socs2
tjp3
uterine
Tagcloud (Intersection)
?