FAM107A and ITPRID2

Number of citations of the paper that reports this interaction (PubMedID 28604741)
0

Data Source:
BioGRID (two hybrid)

		FAM107A	ITPRID2
Description		family with sequence similarity 107 member A	ITPR interacting domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Actin Cytoskeleton Membrane Nuclear Speck Ruffle Membrane Cell Projection Neuron Projection Synapse Anchoring Junction	Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Actin Binding Protein Binding	Actin Binding Signaling Receptor Binding Protein Binding Actin Filament Binding
	Biological Process	Regulation Of Cell Growth Actin Filament Polymerization Positive Regulation Of Cell Migration Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Cellular Response To Nutrient Levels Regulation Of Actin Cytoskeleton Organization Cognition Actin Filament Bundle Assembly Negative Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Cellular Response To Glucocorticoid Stimulus Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917)
Interacting Genes		58 interacting genes: AGMAT APPBP2 AUH AZI2 BEGAIN BIRC8 CALCOCO2 CANX CCDC125 CCDC136 CCDC57 CCDC85B CPSF3 DAPK1 EFEMP2 EFHC2 EIF4A1 ESRRG FKBP6 FSD2 GFM2 GOLGA6L9 HFM1 HOOK2 HSF2BP HSPA14 HSPD1 HTRA1 IQUB ITPRID2 KRT15 KRT19 KRT27 KRT40 KRTAP4-12 LDOC1 LZTS2 MEIOB MID2 MTREX MTUS2 NEXN NFKBID NINL PLSCR1 PNMA1 POMP PSMD6 RAB18 RINT1 RNLS SPATA22 TADA2A TRAF2 TRIM37 USHBP1 VIM WDR47	8 interacting genes: ATXN7 BRCA1 FAM107A KHDRBS1 LUC7L2 PTEN SMARCA2 TSG101
Entrez ID		11170	6744
HPRD ID		09753	00353
Ensembl ID		ENSG00000168309	ENSG00000138434
Uniprot IDs		O95990 Q6IAM1	E7EUL7 E9PHV5 P28290
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton Intermediate Filament Organization Intermediate Filament Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Microtubule Structural Constituent Of Skin Epidermis Meiosis I Cell Cycle Process Female Meiosis I Supramolecular Fiber Organization	Regulation Of Growth Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Growth Regulation Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Focal Adhesion Assembly Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Organelle Organization Negative Regulation Of Mitotic Cell Cycle Molecular Function Inhibitor Activity Negative Regulation Of Growth Negative Regulation Of Cell Cycle Phase Transition Regulation Of DNA Repair Negative Regulation Of Cell-matrix Adhesion Regulation Of Microtubule-based Process Negative Regulation Of Cellular Component Organization Regulation Of Cellular Component Organization Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Process Nucleus Negative Regulation Of Cell Cycle Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell-substrate Adhesion Regulation Of Focal Adhesion Assembly Negative Regulation Of Cell Cycle G1/S Phase Transition Grb2-Sos Complex Regulation Of Protein Stability Regulation Of Cell-substrate Junction Organization Enzyme Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Histone H2AK127 Ubiquitin Ligase Activity Regulation Of Primary Metabolic Process Histone H2AK129 Ubiquitin Ligase Activity Regulation Of RNA Biosynthetic Process BRCA1-BARD1 Complex Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Positive Regulation Of Ubiquitin-dependent Endocytosis Negative Regulation Of Protein Phosphorylation Regulation Of DNA Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process
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