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EPHB2 and ITSN1
Number of citations of the paper that reports this interaction (PubMedID
12389031
)
0
Data Source:
HPRD
(in vivo)
EPHB2
ITSN1
Description
EPH receptor B2
intersectin 1
Image
GO Annotations
Cellular Component
Extracellular Region
Nucleoplasm
Cytosol
Plasma Membrane
Cell Surface
Membrane
Axon
Dendrite
Presynaptic Membrane
Cell Projection
Neuronal Cell Body
Dendritic Spine
Postsynaptic Membrane
Hippocampal Mossy Fiber To CA3 Synapse
Postsynapse
Glutamatergic Synapse
Nucleus
Nuclear Envelope
Cytoplasm
Endosome
Cytosol
Plasma Membrane
Clathrin-coated Pit
Endomembrane System
Membrane
Lamellipodium
Cytoplasmic Vesicle
Presynaptic Membrane
Cell Projection
Neuron Projection
Neuronal Cell Body
Dendritic Spine
Synapse
Recycling Endosome
Apical Dendrite
Intracellular Vesicle
Postsynaptic Endocytic Zone
Postsynaptic Actin Cytoskeleton
Glutamatergic Synapse
Molecular Function
Nucleotide Binding
Amyloid-beta Binding
Protein Kinase Activity
Protein Tyrosine Kinase Activity
Transmembrane Receptor Protein Tyrosine Kinase Activity
Ephrin Receptor Activity
Transmembrane-ephrin Receptor Activity
Signaling Receptor Binding
Protein Binding
ATP Binding
Axon Guidance Receptor Activity
Kinase Activity
Transferase Activity
Signaling Receptor Activity
Identical Protein Binding
Protein-containing Complex Binding
Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Protein-macromolecule Adaptor Activity
Metal Ion Binding
Molecular Adaptor Activity
Proline-rich Region Binding
Biological Process
Cell Morphogenesis
Angiogenesis
Urogenital System Development
Positive Regulation Of Immunoglobulin Production
Negative Regulation Of Cell Adhesion
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Nervous System Development
Axonogenesis
Axon Guidance
Axonal Fasciculation
Learning Or Memory
Learning
Animal Organ Morphogenesis
Positive Regulation Of Gene Expression
Phosphorylation
Peptidyl-tyrosine Phosphorylation
Optic Nerve Morphogenesis
Hindbrain Tangential Cell Migration
Central Nervous System Projection Neuron Axonogenesis
Corpus Callosum Development
Regulation Of Blood Coagulation
Positive Regulation Of Cell Migration
Positive Regulation Of B Cell Proliferation
Retinal Ganglion Cell Axon Guidance
Positive Regulation Of Synaptic Plasticity
Positive Regulation Of Tumor Necrosis Factor Production
B Cell Activation
Inner Ear Morphogenesis
Regulation Of Receptor Signaling Pathway Via JAK-STAT
Negative Regulation Of Ras Protein Signal Transduction
Ephrin Receptor Signaling Pathway
Regulation Of Neuronal Synaptic Plasticity
Positive Regulation Of Long-term Neuronal Synaptic Plasticity
Camera-type Eye Morphogenesis
Regulation Of Axonogenesis
Negative Regulation Of Axonogenesis
Regulation Of Body Fluid Levels
Positive Regulation Of Multicellular Organismal Process
Regulation Of Filopodium Assembly
Regulation Of Synapse Assembly
Positive Regulation Of Synapse Assembly
Roof Of Mouth Development
Dendritic Spine Development
Dendritic Spine Morphogenesis
Positive Regulation Of Dendritic Spine Morphogenesis
Negative Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Lipopolysaccharide
Commissural Neuron Axon Guidance
Postsynaptic Membrane Assembly
Neuron Projection Retraction
Vesicle-mediated Intercellular Transport
Tight Junction Assembly
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Long-term Synaptic Potentiation
Negative Regulation Of Glutamate Receptor Signaling Pathway
Positive Regulation Of Glutamate Receptor Signaling Pathway
Positive Regulation Of Protein Localization To Plasma Membrane
Cellular Response To Amyloid-beta
Neuron Projection Maintenance
Positive Regulation Of Protein Localization To Cell Surface
Regulation Of T-helper 17 Type Immune Response
Regulation Of Autophagosome Assembly
Regulation Of Behavioral Fear Response
Exocytosis
Endocytosis
Intracellular Protein Localization
Regulation Of Cell Communication
Protein Transport
Endosomal Transport
Regulation Of Signaling
Intracellular Signal Transduction
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Growth Hormone Secretion
Positive Regulation Of Dendritic Spine Development
Regulation Of Postsynapse Organization
Clathrin-dependent Synaptic Vesicle Endocytosis
Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Positive Regulation Of Caveolin-mediated Endocytosis
Pathways
EPH-Ephrin signaling
EPH-Ephrin signaling
L1CAM interactions
EPHB-mediated forward signaling
EPHB-mediated forward signaling
Ephrin signaling
Ephrin signaling
EPH-ephrin mediated repulsion of cells
NRAGE signals death through JNK
EPHB-mediated forward signaling
EPHB-mediated forward signaling
G alpha (12/13) signalling events
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
CDC42 GTPase cycle
RHOQ GTPase cycle
RHOG GTPase cycle
Drugs
Phosphoaminophosphonic Acid-Adenylate Ester
Fostamatinib
Oleandrin
Diseases
GWAS
Blood protein levels (
30072576
)
Refractive error (
32231278
)
Triiodothyronine levels (
30843173
)
Triiodothyronine levels and thyroxine levels (
30843173
)
Bitter non-alcoholic beverage consumption (
31046077
)
Educational attainment (
25201988
)
Height (
31562340
)
Mean corpuscular hemoglobin (
27863252
32888494
)
Mean corpuscular hemoglobin concentration (
32888494
)
Mean corpuscular volume (
27863252
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
QT interval (
29213071
)
Red blood cell count (
32888494
)
Red cell distribution width (
27863252
32888494
)
Tonsillectomy (
27182965
28928442
)
Interacting Genes
40 interacting genes:
ABL1
ABL2
ACP1
AFDN
APP
AQP1
ARHGEF6
CRK
EFNA5
EFNB1
EFNB2
ERF
FBXO7
FOS
GRB2
GRIN1
GRIN2B
ITSN1
KALRN
KSR1
MMP2
MMP9
MTMR14
NCK1
PICK1
PLCG1
PTK2
RASA1
RNF186
RRAS
RYK
SDC2
SDCBP
SH2D3C
SRC
SYNJ1
TRIM54
VAV2
VEGFA
YES1
140 interacting genes:
AGFG1
AGFG2
AJUBA
ANKRD36
ANKRD54
ARF6
ARFIP2
ARHGAP31
ASAP2
BECN1
BFSP1
BRCC3
BRWD3
CCDC24
CCNO
CDC42
CEP85L
CLIP2
CLTC
COG4
CSNK2B
CYTH1
CYTH3
DAB1
DAB2
DES
DISC1
DLGAP1
DNAI7
DNAJA2
DNM1
DNM2
DST
DYNC1H1
EEF1A1
EPHB2
EPN2
EPS15
EXOC1
FCHO1
FCHO2
FCHSD2
FNBP1
FNBP4
GAREM2
GCC1
GFAP
GNPTG
GOLGA5
HIP1
HNRNPK
HRAS
IFT74
ITSN2
KHDRBS1
KIF16B
KIF5A
KIF5C
KRT222
LMO3
LMO4
MAP3K20
MAPK6
MAPK8IP2
MED4
MRPL20
MTUS2
MYH14
NASP
NEFL
NEFM
NEMF
PACSIN3
PDCD6IP
PDE2A
PDZD8
PFDN5
PICALM
PIK3AP1
PIK3C2B
PIK3R1
PLK1
PPFIA2
PPL
PREX1
PRRG4
RAB11FIP2
RAB5A
RABEP1
RAI14
RALBP1
REPS1
REPS2
RIN1
RNF40
RPS6KA5
RRBP1
SCAI
SCAMP1
SCOC
SF3B4
SH3GL2
SHANK3
SIAH1
SMARCC2
SMC1A
SNAP23
SNAP25
SNRNP70
SNX5
SNX6
SOS1
SOS2
SPDL1
SPECC1
SPRY2
SPTAN1
SPTBN1
STON2
SYNC
SYNE1
SYNJ1
SYNJ2
TK1
TRAF3IP1
TRIM5
TRIM8
TRPM7
TSG101
TTC27
UBC
UBE2K
UNC119
VLDLR
WASL
WBP11
WHAMM
ZFC3H1
ZFPM2
ZMYM5
Entrez ID
2048
6453
HPRD ID
02997
03898
Ensembl ID
ENSG00000133216
ENSG00000205726
Uniprot IDs
B4DSE0
P29323
Q6NVW1
A7XZY7
F8W7U0
Q15811
Q6PD56
PDB IDs
1B4F
1F0M
2QBX
3ZFM
8EBL
1KI1
2KGR
2KHN
3FIA
3QBV
4IIM
5HZI
5HZJ
5HZK
6GBU
6H5T
Enriched GO Terms of Interacting Partners
?
Ephrin Receptor Signaling Pathway
Ephrin Receptor Binding
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme-linked Receptor Protein Signaling Pathway
Signal Transduction
Phosphotyrosine Residue Binding
Cell Surface Receptor Signaling Pathway
Regulation Of Locomotion
Regulation Of Cell Adhesion
Regulation Of Cellular Component Organization
Plasma Membrane Bounded Cell Projection Organization
Cell Migration
Cell Projection Organization
Positive Regulation Of Cell Migration
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Cell Motility
Positive Regulation Of Locomotion
Cell Motility
Positive Regulation Of Cell Adhesion
Regulation Of Cell-cell Adhesion
Plasma Membrane
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Regulation Of Cell Migration
Regulation Of Cell Projection Organization
Fc Receptor Mediated Stimulatory Signaling Pathway
Intracellular Signal Transduction
Regulation Of Organelle Organization
Fc Receptor Signaling Pathway
Intracellular Signaling Cassette
Regulation Of Cell Motility
Cellular Developmental Process
Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Multicellular Organismal Process
Fc-gamma Receptor Signaling Pathway
Regulation Of Cell-matrix Adhesion
Regulation Of Signal Transduction
ERBB Signaling Pathway
Regulation Of Endocytosis
Positive Regulation Of Immune System Process
Regulation Of Cell-substrate Adhesion
Regulation Of Signaling
Regulation Of Cell Communication
Regulation Of Biological Quality
Regulation Of Neuron Projection Development
Regulation Of Anatomical Structure Morphogenesis
Cellular Response To Oxygen-containing Compound
Cell Differentiation
Non-membrane Spanning Protein Tyrosine Kinase Activity
Positive Regulation Of Multicellular Organismal Process
Endocytosis
Vesicle-mediated Transport
Import Into Cell
Cytoplasm
Cytosol
Establishment Of Localization In Cell
Clathrin-coated Pit
Clathrin Coat Assembly
Cytoskeleton Organization
Organelle Organization
Cytoskeleton
Regulation Of Cellular Component Organization
Receptor-mediated Endocytosis
Organelle Localization
Membrane Organization
Cellular Component Assembly
Clathrin-coated Vesicle
Protein Transport
Clathrin-dependent Endocytosis
Intermediate Filament-based Process
Cellular Localization
Establishment Of Organelle Localization
Intracellular Transport
Negative Regulation Of Cellular Component Organization
Synaptic Vesicle Endocytosis
Establishment Of Protein Localization
Regulation Of Protein Localization To Cell Periphery
Presynaptic Endocytosis
Vesicle-mediated Transport In Synapse
Intermediate Filament Cytoskeleton Organization
Intracellular Protein Localization
Protein-containing Complex Assembly
Clathrin Coat Of Coated Pit
Intermediate Filament Cytoskeleton
Protein-containing Complex Organization
Structural Constituent Of Cytoskeleton
Post-Golgi Vesicle-mediated Transport
Glutamatergic Synapse
Microtubule Binding
Establishment Of Vesicle Localization
Endosomal Transport
Cell Cortex
Cytoplasmic Vesicle
Golgi Vesicle Transport
Regulation Of Protein Localization To Plasma Membrane
Vesicle Localization
Cytoskeleton-dependent Intracellular Transport
Cell Projection Organization
Mitotic Cytokinesis
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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