EPHB2 and ACP1

Number of citations of the paper that reports this interaction (PMID 9499402)
66

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		EPHB2	ACP1
Gene Name		EPH receptor B2	acid phosphatase 1, soluble
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Axon Dendrite Neuronal Cell Body	Cytoplasm Cytoplasmic Side Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Tyrosine Kinase Activity Transmembrane-ephrin Receptor Activity Receptor Binding Protein Binding ATP Binding Axon Guidance Receptor Activity	Acid Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Angiogenesis Urogenital System Development Nervous System Development Axon Guidance Axonal Fasciculation Learning Phosphorylation Peptidyl-tyrosine Phosphorylation Optic Nerve Morphogenesis Central Nervous System Projection Neuron Axonogenesis Corpus Callosum Development Retinal Ganglion Cell Axon Guidance Inner Ear Morphogenesis Ephrin Receptor Signaling Pathway Positive Regulation Of Long-term Neuronal Synaptic Plasticity Camera-type Eye Morphogenesis Negative Regulation Of Axonogenesis Regulation Of Body Fluid Levels Positive Regulation Of Synapse Assembly Palate Development Dendritic Spine Development Dendritic Spine Morphogenesis Commissural Neuron Axon Guidance	Peptidyl-tyrosine Dephosphorylation
Pathways		EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling L1CAM interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		36 interactors: ABL1 ABL2 ACP1 AQP1 ARHGEF6 BCL2 CRK EFNA5 EFNB1 EFNB2 ERF FOS GRB2 GRIN1 GRIN2B ITSN1 KALRN KSR1 MLLT4 MMP2 MMP9 NCK1 PICK1 PLCG1 PTK2 RASA1 RRAS RYK SDC2 SDCBP SH2D3C SRC SYNJ1 VAV2 VEGFA YES1	15 interactors: BARD1 CTNNB1 EPHA2 EPHB1 EPHB2 FABP4 FNBP1L FYN INSR KDR LCK MRPL20 SFMBT1 SPTAN1 ZAP70
Entrez ID		2048	52
HPRD ID		02997	08881
Ensembl ID		ENSG00000133216	ENSG00000143727
Uniprot IDs		P29323	B5MCC7 P24666 Q59EH3
PDB IDs		1B4F 1F0M 2QBX	1XWW 3N8I 5PNT
Enriched GO Terms of Interacting Partners?		Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Ephrin Receptor Signaling Pathway Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Chemotaxis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neuron Projection Development Neuron Development Cell Projection Morphogenesis Cell Projection Organization Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Neuron Differentiation Cell Morphogenesis Response To External Stimulus Generation Of Neurons Cell Development Neurogenesis Locomotion Nervous System Development Movement Of Cell Or Subcellular Component Anatomical Structure Morphogenesis Signaling Cell Communication Cell Differentiation Cell Surface Receptor Signaling Pathway Signal Transduction Regulation Of Intracellular Signal Transduction System Development Regulation Of Signaling Cellular Response To Stimulus Anatomical Structure Development Multicellular Organismal Development Developmental Process Regulation Of Signal Transduction Regulation Of Phosphorylation Positive Regulation Of Metabolic Process Response To Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Phagocytosis Immune Response-regulating Cell Surface Receptor Signaling Pathway Fc Receptor Signaling Pathway Cell Migration Regulation Of Phosphorus Metabolic Process	Peptidyl-tyrosine Phosphorylation Peptidyl-tyrosine Autophosphorylation Protein Autophosphorylation Movement Of Cell Or Subcellular Component Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Locomotion Enzyme Linked Receptor Protein Signaling Pathway Peptidyl-amino Acid Modification Ephrin Receptor Signaling Pathway Cell Migration Developmental Process Regulation Of Phosphorylation Protein Phosphorylation Cell Differentiation Regulation Of Cellular Component Organization Cell Motility Camera-type Eye Morphogenesis Regulation Of Phosphorus Metabolic Process Response To Growth Factor Positive Regulation Of Cellular Component Biogenesis Regulation Of Cell Adhesion Angiogenesis Cell Morphogenesis Eye Morphogenesis Cell Morphogenesis Involved In Differentiation Axon Guidance Anatomical Structure Morphogenesis Regulation Of Intracellular Signal Transduction Blood Vessel Morphogenesis Phosphorylation Positive Regulation Of Intracellular Signal Transduction Optic Nerve Morphogenesis Cell Projection Morphogenesis Positive Regulation Of Cell Differentiation Cell Part Morphogenesis Cardiovascular System Development Dendrite Morphogenesis Blood Vessel Development Axonogenesis Vasculature Development Dendritic Spine Morphogenesis Viral Process Anatomical Structure Development Organ Development Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation T Cell Aggregation T Cell Activation Optic Nerve Development
Tagcloud ?		10a1 10ca1a 3d array beta3 emt ephrin impede inhibits integrin interplay intricate invasion mcf mesenchymal metallo migration mmp9 modulated nmumg nutlin p53 proteinase spheroid tgf transforming transwell verification whereby	ada ada2 additive adenosine allele approved cad carriers codon committee consent contribution deaminase diabetic donors ethical functionally give hints informed multifactorial note phosphatse proportion ptpn22 simultaneous strength stresses written
Tagcloud (Difference) ?		10a1 10ca1a 3d array beta3 emt ephrin impede inhibits integrin interplay intricate invasion mcf mesenchymal metallo migration mmp9 modulated nmumg nutlin p53 proteinase spheroid tgf transforming transwell verification whereby	ada ada2 additive adenosine allele approved cad carriers codon committee consent contribution deaminase diabetic donors ethical functionally give hints informed multifactorial note phosphatse proportion ptpn22 simultaneous strength stresses written
Tagcloud (Intersection) ?