ACTN3 and NRAP

Number of citations of the paper that reports this interaction (PMID 12692149)
12

Data Source:
HPRD (two hybrid, in vitro)

		ACTN3	NRAP
Gene Name		actinin, alpha 3 (gene/pseudogene)	nebulin-related anchoring protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Actin Filament Focal Adhesion Pseudopodium Extracellular Vesicular Exosome	Fascia Adherens Muscle Tendon Junction
	Molecular Function	Actin Binding Integrin Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Protein Homodimerization Activity	Actin Binding Zinc Ion Binding Muscle Alpha-actinin Binding
	Biological Process	Muscle Filament Sliding Regulation Of Apoptotic Process Focal Adhesion Assembly	Biological_process
Pathways		Striated Muscle Contraction Nephrin interactions
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		17 interactors: ABI3 ACTN1 ACTN2 ACTN4 ADORA2A BRCA1 C1orf94 KCTD6 MYPN NEBL NRAP PLEKHG2 REL RNF111 SUMO1P1 TRAF1 TRAF2	8 interactors: ACTA1 ACTB ACTN3 KLHL41 PRKAA2 TLN1 TRIM63 VCL
Entrez ID		89	4892
HPRD ID		02148	04189
Ensembl ID		ENSG00000248746	ENSG00000197893
Uniprot IDs		B4DZQ2 Q08043 Q4VAM3	Q86VF7
PDB IDs		1TJT 1WKU 3LUE
Enriched GO Terms of Interacting Partners?		Protein Localization To Tight Junction Regulation Of Cell Death Cellular Component Assembly Protein Localization To Cell Junction Platelet Degranulation Regulation Of Apoptotic Process Actin Filament-based Process Actin Crosslink Formation Blood Coagulation Hemostasis Protein Polyubiquitination Focal Adhesion Assembly Platelet Activation Apoptotic Process Cell Junction Assembly Regulation Of Extrinsic Apoptotic Signaling Pathway NIK/NF-kappaB Signaling Cell-cell Junction Organization Programmed Cell Death Protein Autoubiquitination Cell Death Death Regulation Of Body Fluid Levels Tight Junction Assembly Adherens Junction Assembly Actin Cytoskeleton Organization Wound Healing Cytoskeleton Organization Positive Regulation Of Ion Transmembrane Transporter Activity Cell-substrate Junction Assembly Protein Homooligomerization Positive Regulation Of Transporter Activity I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Cardiac Muscle Thin Filament Assembly Actin Filament Bundle Assembly Response To Wounding Regulation Of Signal Transduction Actin Filament Organization Apical Junction Assembly Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Ion Transmembrane Transport Myofibril Assembly Exocytosis Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Cytokine Production Adherens Junction Organization Regulation Of Signaling Cellular Response To Tumor Necrosis Factor	Muscle Contraction Muscle System Process Platelet Aggregation Cell Junction Assembly Cell-cell Junction Organization Adherens Junction Organization Skeletal Muscle Adaptation Cellular Component Assembly Platelet Activation Actin Filament-based Process Movement Of Cell Or Subcellular Component Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Adherens Junction Assembly Cell Development Cell-substrate Junction Assembly Homotypic Cell-cell Adhesion Actin Filament-based Movement Platelet Degranulation Blood Coagulation Myofibril Assembly Hemostasis Regulation Of Lateral Pseudopodium Assembly Cell Adhesion Anatomical Structure Morphogenesis Axonogenesis Single Organismal Cell-cell Adhesion Actomyosin Structure Organization Skeletal Muscle Fiber Adaptation Cell-cell Junction Assembly Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Actin Cytoskeleton Organization Skeletal Muscle Tissue Development Neuron Projection Morphogenesis Cell Growth Skeletal Muscle Organ Development Cell Activation Striated Muscle Cell Development Response To Wounding Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Cell Morphogenesis Involved In Differentiation Cell-matrix Adhesion Muscle Cell Development Organelle Organization Response To External Stimulus Skeletal Muscle Atrophy
Tagcloud ?		ace bdkrb2 chi2 cl cmj competition counter discriminate distributions elite explosive forward genotypic italian italians jump leg look players sedentary sj soccer squat stepwise strength top traits variance
Tagcloud (Difference) ?		ace bdkrb2 chi2 cl cmj competition counter discriminate distributions elite explosive forward genotypic italian italians jump leg look players sedentary sj soccer squat stepwise strength top traits variance
Tagcloud (Intersection) ?