ACTN3 and MYPN

Number of citations of the paper that reports this interaction (PMID 11309420)
43

Data Source:
HPRD (two hybrid)

		ACTN3	MYPN
Gene Name		actinin, alpha 3 (gene/pseudogene)	myopalladin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Actin Filament Focal Adhesion Pseudopodium Extracellular Vesicular Exosome	Nucleus Z Disc I Band
	Molecular Function	Actin Binding Integrin Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Protein Homodimerization Activity	Actin Binding Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding Muscle Alpha-actinin Binding
	Biological Process	Muscle Filament Sliding Regulation Of Apoptotic Process Focal Adhesion Assembly	Sarcomere Organization
Pathways		Striated Muscle Contraction Nephrin interactions
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Optic disc size (disc) ( 20395239)
Protein-Protein Interactions		17 interactors: ABI3 ACTN1 ACTN2 ACTN4 ADORA2A BRCA1 C1orf94 KCTD6 MYPN NEBL NRAP PLEKHG2 REL RNF111 SUMO1P1 TRAF1 TRAF2	7 interactors: ACTN2 ACTN3 ANKRD1 ANKRD23 NEB NEBL TTN
Entrez ID		89	84665
HPRD ID		02148	10536
Ensembl ID		ENSG00000248746	ENSG00000138347
Uniprot IDs		B4DZQ2 Q08043 Q4VAM3	Q86TC9
PDB IDs		1TJT 1WKU 3LUE
Enriched GO Terms of Interacting Partners?		Protein Localization To Tight Junction Regulation Of Cell Death Cellular Component Assembly Protein Localization To Cell Junction Platelet Degranulation Regulation Of Apoptotic Process Actin Filament-based Process Actin Crosslink Formation Blood Coagulation Hemostasis Protein Polyubiquitination Focal Adhesion Assembly Platelet Activation Apoptotic Process Cell Junction Assembly Regulation Of Extrinsic Apoptotic Signaling Pathway NIK/NF-kappaB Signaling Cell-cell Junction Organization Programmed Cell Death Protein Autoubiquitination Cell Death Death Regulation Of Body Fluid Levels Tight Junction Assembly Adherens Junction Assembly Actin Cytoskeleton Organization Wound Healing Cytoskeleton Organization Positive Regulation Of Ion Transmembrane Transporter Activity Cell-substrate Junction Assembly Protein Homooligomerization Positive Regulation Of Transporter Activity I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Cardiac Muscle Thin Filament Assembly Actin Filament Bundle Assembly Response To Wounding Regulation Of Signal Transduction Actin Filament Organization Apical Junction Assembly Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Ion Transmembrane Transport Myofibril Assembly Exocytosis Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Cytokine Production Adherens Junction Organization Regulation Of Signaling Cellular Response To Tumor Necrosis Factor	Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Actin Filament-based Process Muscle Contraction Muscle System Process Myofibril Assembly Response To Muscle Stretch Actomyosin Structure Organization Muscle Structure Development Striated Muscle Cell Development Muscle Cell Development Cardiac Muscle Tissue Development Cardiac Myofibril Assembly Response To Mechanical Stimulus Striated Muscle Cell Differentiation Focal Adhesion Assembly Muscle Organ Development Cellular Component Assembly Striated Muscle Tissue Development Adherens Junction Assembly Muscle Cell Differentiation Muscle Tissue Development Cell-substrate Junction Assembly Sarcomere Organization Cardiac Muscle Tissue Morphogenesis Muscle Tissue Morphogenesis Cardiac Muscle Cell Development Muscle Organ Morphogenesis Platelet Degranulation Organelle Assembly Adherens Junction Organization Cardiac Muscle Thin Filament Assembly Heart Development Cardiac Muscle Cell Differentiation Movement Of Cell Or Subcellular Component Actin Cytoskeleton Organization Cardiocyte Differentiation Sarcomerogenesis Detection Of Muscle Stretch Skeletal Muscle Myosin Thick Filament Assembly Cell-matrix Adhesion Directional Locomotion Platelet Activation Myosin Filament Assembly Cell Junction Assembly Cardiovascular System Development Cell-cell Junction Organization Cell-substrate Adhesion
Tagcloud ?		ace bdkrb2 chi2 cl cmj competition counter discriminate distributions elite explosive forward genotypic italian italians jump leg look players sedentary sj soccer squat stepwise strength top traits variance
Tagcloud (Difference) ?		ace bdkrb2 chi2 cl cmj competition counter discriminate distributions elite explosive forward genotypic italian italians jump leg look players sedentary sj soccer squat stepwise strength top traits variance
Tagcloud (Intersection) ?