SPMIP9 and VAC14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPMIP9	VAC14
Description		sperm microtubule inner protein 9	VAC14 component of PIKFYVE complex
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath	Golgi Membrane Endosome Endoplasmic Reticulum Cytosol Endosome Membrane Membrane Early Endosome Membrane Late Endosome Membrane PAS Complex Presynaptic Endosome
	Molecular Function	Protein Binding	Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process	Flagellated Sperm Motility	Phosphatidylinositol Biosynthetic Process Signal Transduction Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Pathways			Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the late endosome membrane
Drugs
Diseases
GWAS			Diffuse cutaneous systemic sclerosis ( 29293537) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) High density lipoprotein cholesterol levels ( 28548082) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061) Pulse pressure ( 28135244)
Interacting Genes		44 interacting genes: ANAPC11 APP ATXN1L BSCL2 CAMK2A CTRC CYSRT1 DAZAP2 FOXD2 HOXC9 KCTD9 KLHDC7B KPNA3 KRTAP12-2 KRTAP12-4 KRTAP13-2 KRTAP19-5 KRTAP19-7 KRTAP23-1 KRTAP26-1 KRTAP3-1 KRTAP6-2 MAGEA11 OTX1 PITX2 PLAC8 PRR30 RBFOX1 RBFOX2 RBPMS RBPMS2 RNF44 SOX14 TFAP2D TFG TLE5 TLX3 TRIP13 UBAP2 VAC14 VGLL3 WWOX ZBTB32 ZC3H10	107 interacting genes: ABHD11 ACSS1 ACTMAP AMT APP ARID5A ASB13 ATM BCL2L1 BHLHE40 BKGD C4orf33 CASP1 CATSPERT CD209 CDRT4 CNTN2 COL8A1 CRK CRYBA1 CRYBA2 DDAH2 DNAAF19 EEF1AKMT3 EHHADH EIF2S1 EIF6 FAM50B FNDC3B GABPB2 GALT GINS3 GLIS2 GNB1 GTF3C2 HDHD3 HNF1B HNRNPLL INTS11 JMJD7 KHDC1 KRABD5 KRT82 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LINC00518 LPAL2 MBLAC1 MEOX2 METTL15 MGAT5B MPPED2 MTMR9 MVP MYOZ1 NDUFAB1 NGB NOS1 NTAQ1 OIT3 OTOS PBLD PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PPP6C PRADC1 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E RBFOX2 RHBDL1 RHOXF2 RIPPLY1 RNASEH2C RSKR SIGLEC5 SMUG1 SNF8 SPMIP9 SPRYD7 SRPK2 TCEANC TP53BP1 TRIM55 TRIM63 UFSP1 VENTX VHLL WDR83 WRAP53 ZBTB49 ZCWPW1 ZNF34
Entrez ID		200523	55697
HPRD ID		08688	07660
Ensembl ID		ENSG00000172073	ENSG00000103043
Uniprot IDs		A0A140VK60 Q96LM6	Q08AM6
PDB IDs			7K1Y
Enriched GO Terms of Interacting Partners?		Intermediate Filament Regulation Of RNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Identical Protein Binding Regulation Of RNA Biosynthetic Process Cytoplasmic Stress Granule Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Protein Binding Regulation Of Gene Expression Regulation Of MRNA Processing Regulation Of Macromolecule Biosynthetic Process	Protein Binding Intermediate Filament
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