SPMIP9 and SOX14

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		SPMIP9	SOX14
Name		sperm microtubule inner protein 9	SRY-box transcription factor 14
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Flagellated Sperm Motility	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Nervous System Development Brain Development Visual Perception Entrainment Of Circadian Clock Neuron Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Neuron Migration
GWAS		No GWAS studies recorded	Alzheimer's disease in APOE e4- carriers ( 25778476 ) Glucocorticoid-induced osteonecrosis ( 26265699 )
Interacting Genes		44 interacting genes: ANAPC11 APP ATXN1L BSCL2 CAMK2A CTRC CYSRT1 DAZAP2 FOXD2 HOXC9 KCTD9 KLHDC7B KPNA3 KRTAP12-2 KRTAP12-4 KRTAP13-2 KRTAP19-5 KRTAP19-7 KRTAP23-1 KRTAP26-1 KRTAP3-1 KRTAP6-2 MAGEA11 OTX1 PITX2 PLAC8 PRR30 RBFOX1 RBFOX2 RBPMS RBPMS2 RNF44 SOX14 TFAP2D TFG TLE5 TLX3 TRIP13 UBAP2 VAC14 VGLL3 WWOX ZBTB32 ZC3H10	9 interacting genes: CRX FOXH1 KRTAP15-1 NAIF1 ROR2 SPMIP9 TRIM54 VENTX ZDHHC17
Entrez ID		200523	8403
HPRD ID		08688	16067
Ensembl ID		ENSG00000172073	ENSG00000168875
Uniprot IDs		A0A140VK60 Q96LM6	O95416
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Intermediate Filament Regulation Of RNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Identical Protein Binding Regulation Of RNA Biosynthetic Process Cytoplasmic Stress Granule Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Protein Binding Regulation Of Gene Expression Regulation Of MRNA Processing Regulation Of Macromolecule Biosynthetic Process	None