DUT and PLEKHF2

Number of citations of the paper that reports this interaction (PMID 19060904)
157

Data Source:
BioGRID (two hybrid)

		DUT	PLEKHF2
Gene Name		deoxyuridine triphosphatase	pleckstrin homology domain containing, family F (with FYVE domain) member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Extracellular Vesicular Exosome	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane
	Molecular Function	Magnesium Ion Binding DUTP Diphosphatase Activity Protein Binding Poly(A) RNA Binding	Protein Binding Metal Ion Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Metabolic Process DUMP Biosynthetic Process DNA Replication Small Molecule Metabolic Process DUTP Catabolic Process Pyrimidine Nucleoside Biosynthetic Process Nucleobase-containing Small Molecule Metabolic Process	Protein Transport
Pathways
Drugs		Deoxyuridine-5\'-Diphosphate 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
Diseases
GWAS		Protein quantitative trait loci ( 18464913)	Radiation response ( 20923822)
Protein-Protein Interactions		9 interactors: CDK1 ESR1 ESRRA ESRRG NUDT18 PLEKHF2 PPARA PPARD SPATA2	52 interactors: ACY3 AIMP2 APP APPL1 BEND7 BLOC1S6 BSCL2 CCDC85B CEP44 CHIC2 DTX2 DUT FBXO28 FHL3 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NONO NPM2 PRKAR1A PRPSAP1 RABAC1 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SDPR SEPT2 SEPT6 SETBP1 SFN SPEF1 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z ZNF250 ZNF263 ZNF398
Entrez ID		1854	79666
HPRD ID		03165	15147
Ensembl ID		ENSG00000128951	ENSG00000175895
Uniprot IDs		H0YNW5 P33316	Q9H8W4
PDB IDs		1Q5H 1Q5U 2HQU 3ARA 3ARN 3EHW 4FDR 4FDS
Enriched GO Terms of Interacting Partners?		Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Cellular Response To Hormone Stimulus Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Organic Cyclic Compound Response To Hormone Response To Steroid Hormone Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Response To Lipid Positive Regulation Of Cellular Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Positive Regulation Of Transcription, DNA-templated Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Response To Activity Tissue Development Fatty Acid Transport Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Reproduction Regulation Of Glycolytic By Positive Regulation Of Transcription From RNA Polymerase II Promoter DGDP Catabolic Process DADP Catabolic Process GDP Catabolic Process Pronuclear Fusion Maternal Process Involved In Female Pregnancy Cellular Nitrogen Compound Metabolic Process Epithelial Cell Proliferation Positive Regulation Of Metabolic Process Single Organism Reproductive Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Heart Development Nitrogen Compound Metabolic Process RNA Biosynthetic Process Reproductive Process Negative Regulation Of Gene Expression Monocarboxylic Acid Transport	Apoptotic Process Programmed Cell Death Cell Death Death Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		100mg alloxan antioxidant apiculata chlorpropamide commercial diabetic dt estimated extract extracts hypoglycaemic hypoglycemic leaf malondialdehyde mellitus methanolic ndt nut oliv peritoneal possess practitioners property raised tacazzea untreated weekly withdrawal	abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering
Tagcloud (Difference) ?		100mg alloxan antioxidant apiculata chlorpropamide commercial diabetic dt estimated extract extracts hypoglycaemic hypoglycemic leaf malondialdehyde mellitus methanolic ndt nut oliv peritoneal possess practitioners property raised tacazzea untreated weekly withdrawal	abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering
Tagcloud (Intersection) ?