DUT and SPATA2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DUT	SPATA2
Description		deoxyuridine triphosphatase	spermatogenesis associated 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Extracellular Exosome	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Magnesium Ion Binding RNA Binding DUTP Diphosphatase Activity Protein Binding Hydrolase Activity Signaling Receptor Inhibitor Activity Pyrimidine Deoxyribonucleotide Binding Identical Protein Binding Peroxisome Proliferator Activated Receptor Binding	Protein Binding Signaling Receptor Complex Adaptor Activity Protein-containing Complex Binding Ubiquitin-specific Protease Binding
	Biological Process	Liver Development Nucleobase-containing Compound Metabolic Process DUMP Biosynthetic Process DTMP Biosynthetic Process DNA Replication Nucleotide Metabolic Process Pyrimidine Deoxyribonucleoside Monophosphate Biosynthetic Process Pyrimidine Deoxyribonucleotide Biosynthetic Process Regulation Of Protein-containing Complex Assembly DUTP Catabolic Process	Spermatogenesis Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Programmed Cell Death Regulation Of Inflammatory Response Regulation Of Necroptotic Process Necroptotic Process Protein K63-linked Deubiquitination Seminiferous Tubule Development Protein Linear Deubiquitination
Pathways			TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NF-kappa-B signaling pathway
Drugs		Deoxyuridine-5'-Diphosphate 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
Diseases
GWAS		Blood protein levels ( 30072576) Height ( 31562340) Protein quantitative trait loci ( 18464913) Skin pigmentation ( 28300201)	Coronary artery disease ( 29212778) Gut microbiota (beta diversity) ( 27723756) Psoriasis ( 18364390 20953189 25574825)
Interacting Genes		10 interacting genes: BCAS2 CDK1 ESR1 ESRRA ESRRG NUDT18 PLEKHF2 PPARA PPARD SPATA2	22 interacting genes: ANKRD11 APP ATP6V1H CATSPERT CCDC102B CEP72 DUT EFHC1 GOLGA2 GPANK1 KAT5 KIFC3 LENG1 MAD1L1 OTULIN PTPN6 TBC1D22B TNIP1 TRAF2 TRIM27 UBC ZNF835
Entrez ID		1854	9825
HPRD ID		03165	09636
Ensembl ID		ENSG00000128951	ENSG00000158480
Uniprot IDs		A0A0C4DGL3 H0YNW5 P33316	A8K0S9 B4DID4 Q9UM82
PDB IDs		1Q5H 1Q5U 2HQU 3ARA 3ARN 3EHW 4MZ5 4MZ6 5H4J 7PWJ 8C8I	5LJM 5LJN
Enriched GO Terms of Interacting Partners?		Nuclear Steroid Receptor Activity Nuclear Receptor Activity Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Nuclear Receptor-mediated Signaling Pathway Hormone-mediated Signaling Pathway Estrogen Response Element Binding Intracellular Receptor Signaling Pathway Negative Regulation Of MiRNA Transcription Steroid Binding Sequence-specific DNA Binding Transcription Coactivator Binding Regulation Of MiRNA Transcription Negative Regulation Of Cholesterol Storage Regulation Of MiRNA Metabolic Process DNA-binding Transcription Factor Activity Positive Regulation Of Fatty Acid Oxidation Regulation Of Inflammatory Response DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Lipid Storage Regulation Of Fatty Acid Oxidation Intracellular Signal Transduction Response To Wounding Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Nucleoplasm Positive Regulation Of Fatty Acid Metabolic Process Sequence-specific Double-stranded DNA Binding Fibroblast Proliferation Zinc Ion Binding Regulation Of Lipid Storage Positive Regulation Of Nucleobase-containing Compound Metabolic Process Rhythmic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Epithelial Cell Apoptotic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Pronuclear Fusion Positive Regulation Of Transformation Of Host Cell By Virus Linoleic Acid Binding 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process Regulation Of Heart Growth Regulation Of Developmental Growth Regulation Of Programmed Cell Death Lipid Binding Wound Healing Response To Activity Regulation Of Defense Response	Microtubule-based Process Spindle Pole Pattern Recognition Receptor Signaling Pathway CD27 Signaling Pathway Positive Regulation Of Mitotic Sister Chromatid Segregation Innate Immune Response-activating Signaling Pathway Innate Immune Response Activation Of Innate Immune Response Regulation Of Metaphase Plate Congression Identical Protein Binding Regulation Of Innate Immune Response Defense Response To Symbiont Defense Response To Other Organism Positive Regulation Of Defense Response Cytoplasmic Pattern Recognition Receptor Signaling Pathway Attachment Of Mitotic Spindle Microtubules To Kinetochore Protein Serine/threonine Kinase Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Immune Response Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Defense Response Response To External Biotic Stimulus DUTP Catabolic Process DUTP Diphosphatase Activity Spindle Organization Positive Regulation Of Protein Modification Process Mitotic Spindle Regulation Of Autophagy Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of Innate Immune Response Epididymis Development Immune Response-activating Signaling Pathway TORC2 Complex Disassembly Mitotic Spindle Pole Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Chromosome Segregation MAD1 Complex Histone H2AK5 Acetyltransferase Activity Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Microtubule-based Movement Regulation Of Cytokine-mediated Signaling Pathway Cytoskeleton Immune Response-regulating Signaling Pathway Regulation Of Inflammatory Response Activation Of Immune Response
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?