DUT and SPATA2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DUT	SPATA2
Gene Name		deoxyuridine triphosphatase	spermatogenesis associated 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Extracellular Vesicular Exosome	Nucleus Nucleolus Cytoplasm
	Molecular Function	Magnesium Ion Binding DUTP Diphosphatase Activity Protein Binding Poly(A) RNA Binding	Molecular_function
	Biological Process	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Metabolic Process DUMP Biosynthetic Process DNA Replication Small Molecule Metabolic Process DUTP Catabolic Process Pyrimidine Nucleoside Biosynthetic Process Nucleobase-containing Small Molecule Metabolic Process	Multicellular Organismal Development Spermatogenesis Cell Differentiation
Pathways
Drugs		Deoxyuridine-5\'-Diphosphate 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
Diseases
GWAS		Protein quantitative trait loci ( 18464913)	Psoriasis ( 20953189 18364390)
Protein-Protein Interactions		9 interactors: CDK1 ESR1 ESRRA ESRRG NUDT18 PLEKHF2 PPARA PPARD SPATA2	9 interactors: APP CEP72 DUT GOLGA2 LZTS2 MAD1L1 PTPN6 TRAF2 TRIM27
Entrez ID		1854	9825
HPRD ID		03165	09636
Ensembl ID		ENSG00000128951	ENSG00000158480
Uniprot IDs		H0YNW5 P33316	A8K0S9 B4DID4 Q9UM82
PDB IDs		1Q5H 1Q5U 2HQU 3ARA 3ARN 3EHW 4FDR 4FDS
Enriched GO Terms of Interacting Partners?		Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Cellular Response To Hormone Stimulus Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Organic Cyclic Compound Response To Hormone Response To Steroid Hormone Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Response To Lipid Positive Regulation Of Cellular Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Positive Regulation Of Transcription, DNA-templated Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Response To Activity Tissue Development Fatty Acid Transport Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Reproduction Regulation Of Glycolytic By Positive Regulation Of Transcription From RNA Polymerase II Promoter DGDP Catabolic Process DADP Catabolic Process GDP Catabolic Process Pronuclear Fusion Maternal Process Involved In Female Pregnancy Cellular Nitrogen Compound Metabolic Process Epithelial Cell Proliferation Positive Regulation Of Metabolic Process Single Organism Reproductive Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Heart Development Nitrogen Compound Metabolic Process RNA Biosynthetic Process Reproductive Process Negative Regulation Of Gene Expression Monocarboxylic Acid Transport	Mitotic Cell Cycle Regulation Of Cellular Localization Regulation Of Protein Binding Regulation Of Adaptive Immune Response Regulation Of Mitotic Cell Cycle Phase Transition Cell Cycle Regulation Of Cell Cycle Phase Transition Protein K63-linked Ubiquitination Protein Trimerization Negative Regulation Of Adaptive Immune Response Regulation Of Protein Kinase Activity Regulation Of Binding Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process Innate Immune Response Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Mitotic Cell Cycle DUMP Biosynthetic Process Regulation Of Metaphase Plate Congression DUTP Catabolic Process Regulation Of Protein Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Process Abortive Mitotic Cell Cycle Negative Regulation Of Interleukin-2 Secretion Gamma-tubulin Complex Localization Synaptic Growth At Neuromuscular Junction Immune Response Regulation Of Phosphorylation Defense Response Spindle Organization Negative Regulation Of Immune Response DUMP Metabolic Process Collateral Sprouting In Absence Of Injury DUTP Metabolic Process Positive Regulation Of Peptidase Activity Regulation Of Phosphorus Metabolic Process Regulation Of Proteolysis Mitotic Cell Cycle Process Protein Polyubiquitination Negative Regulation Of B Cell Receptor Signaling Pathway Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Calcium Ion Import Regulation Of Calcium Ion Transport Platelet Activation Microtubule-based Process
Tagcloud ?		100mg alloxan antioxidant apiculata chlorpropamide commercial diabetic dt estimated extract extracts hypoglycaemic hypoglycemic leaf malondialdehyde mellitus methanolic ndt nut oliv peritoneal possess practitioners property raised tacazzea untreated weekly withdrawal
Tagcloud (Difference) ?		100mg alloxan antioxidant apiculata chlorpropamide commercial diabetic dt estimated extract extracts hypoglycaemic hypoglycemic leaf malondialdehyde mellitus methanolic ndt nut oliv peritoneal possess practitioners property raised tacazzea untreated weekly withdrawal
Tagcloud (Intersection) ?