PLEKHF2 and MEAF6

Number of citations of the paper that reports this interaction (PMID 19060904)
157

Data Source:
BioGRID (two hybrid, two hybrid)

		PLEKHF2	MEAF6
Gene Name		pleckstrin homology domain containing, family F (with FYVE domain) member 2	MYST/Esa1-associated factor 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane	Nucleoplasm Nucleolus Cytoplasm Centrosome NuA4 Histone Acetyltransferase Complex MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Protein Transport	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone H2A Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Histone H3-K14 Acetylation
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Radiation response ( 20923822)
Protein-Protein Interactions		52 interactors: ACY3 AIMP2 APP APPL1 BEND7 BLOC1S6 BSCL2 CCDC85B CEP44 CHIC2 DTX2 DUT FBXO28 FHL3 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NONO NPM2 PRKAR1A PRPSAP1 RABAC1 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SDPR SEPT2 SEPT6 SETBP1 SFN SPEF1 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z ZNF250 ZNF263 ZNF398	9 interactors: BRPF1 CCDC85B FXR2 JADE1 L3MBTL2 LDOC1 MRGBP PLEKHF2 TRIM54
Entrez ID		79666	64769
HPRD ID		15147	13347
Ensembl ID		ENSG00000175895
Uniprot IDs		Q9H8W4	Q9HAF1
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Cellular Metabolic Process	Chromatin Modification Chromatin Organization Histone H3 Acetylation Chromosome Organization Transcription, DNA-templated Histone Acetylation Internal Peptidyl-lysine Acetylation RNA Biosynthetic Process Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Growth Negative Regulation Of Cell Growth RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Growth Histone H4-K12 Acetylation Peptidyl-lysine Modification Gene Expression Histone H4-K5 Acetylation Histone H4-K8 Acetylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Cell Growth Histone Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Microtubule Depolymerization Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Microtubule Polymerization Or Depolymerization Heterocycle Metabolic Process Regulation Of Cellular Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Histone H4 Acetylation
Tagcloud ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering
Tagcloud (Difference) ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering
Tagcloud (Intersection) ?