PLEKHF2 and BSCL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PLEKHF2	BSCL2
Gene Name		pleckstrin homology domain containing, family F (with FYVE domain) member 2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane	Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Metal Ion Binding	Molecular_function
	Biological Process	Protein Transport	Lipid Catabolic Process Lipid Storage Lipid Particle Organization Fat Cell Differentiation Negative Regulation Of Lipid Catabolic Process
Pathways
Drugs
Diseases
GWAS		Radiation response ( 20923822)
Protein-Protein Interactions		52 interactors: ACY3 AIMP2 APP APPL1 BEND7 BLOC1S6 BSCL2 CCDC85B CEP44 CHIC2 DTX2 DUT FBXO28 FHL3 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NONO NPM2 PRKAR1A PRPSAP1 RABAC1 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SDPR SEPT2 SEPT6 SETBP1 SFN SPEF1 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z ZNF250 ZNF263 ZNF398	6 interactors: NSG1 PLEKHF2 SMIM3 SMLR1 TMEM19 USE1
Entrez ID		79666	26580
HPRD ID		15147	05858
Ensembl ID		ENSG00000175895	ENSG00000168000
Uniprot IDs		Q9H8W4	Q96G97
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Cellular Metabolic Process	Endoplasmic Reticulum Tubular Network Organization Regulation Of ER To Golgi Vesicle-mediated Transport Clathrin Coat Assembly Dopamine Receptor Signaling Pathway Lysosomal Transport Endoplasmic Reticulum Organization Transport Membrane Budding Vacuolar Transport Protein Transport Establishment Of Protein Localization
Tagcloud ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering	adipocyte adipogenesis adipose autonomous berardinelli bring cgl cgls congenital contributions cytoskeletal depots droplet handful ld lipin lipodystrophic lipodystrophy localizes mechanistically partners recapitulate remodelling scaffolding seip seipin storage termini truncations
Tagcloud (Difference) ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering	adipocyte adipogenesis adipose autonomous berardinelli bring cgl cgls congenital contributions cytoskeletal depots droplet handful ld lipin lipodystrophic lipodystrophy localizes mechanistically partners recapitulate remodelling scaffolding seip seipin storage termini truncations
Tagcloud (Intersection) ?