PLEKHF2 and FRMD8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PLEKHF2	FRMD8
Gene Name		pleckstrin homology domain containing, family F (with FYVE domain) member 2	FERM domain containing 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane	Cytoskeleton
	Molecular Function	Protein Binding Metal Ion Binding
	Biological Process	Protein Transport
Pathways
Drugs
Diseases
GWAS		Radiation response ( 20923822)
Protein-Protein Interactions		52 interactors: ACY3 AIMP2 APP APPL1 BEND7 BLOC1S6 BSCL2 CCDC85B CEP44 CHIC2 DTX2 DUT FBXO28 FHL3 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NONO NPM2 PRKAR1A PRPSAP1 RABAC1 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SDPR SEPT2 SEPT6 SETBP1 SFN SPEF1 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z ZNF250 ZNF263 ZNF398	4 interactors: APP GRAMD3 IKBKG PLEKHF2
Entrez ID		79666	83786
HPRD ID		15147	13326
Ensembl ID		ENSG00000175895	ENSG00000126391
Uniprot IDs		Q9H8W4	B4E2P1 Q9BZ67
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Cellular Metabolic Process	Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Copper Ion Homeostasis Suckling Behavior Regulation Of Protein Kinase Activity Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Kinase Activity Activation Of NF-kappaB-inducing Kinase Activity Innate Immune Response Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Positive Regulation Of NIK/NF-kappaB Signaling Mating Behavior B Cell Homeostasis Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition NIK/NF-kappaB Signaling Apoptotic Process Regulation Of NIK/NF-kappaB Signaling Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Death Death Regulation Of Protein Phosphorylation Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Cellular Protein Metabolic Process Axon Cargo Transport Mating Neuromuscular Junction Development Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Positive Regulation Of Mitotic Cell Cycle Phase Transition I-kappaB Kinase/NF-kappaB Signaling Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Toll-like Receptor TLR6:TLR2 Signaling Pathway
Tagcloud ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering
Tagcloud (Difference) ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering
Tagcloud (Intersection) ?