DUT

Gene Name		deoxyuridine triphosphatase
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding DUTP Diphosphatase Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Metabolic Process DUMP Biosynthetic Process DNA Replication Small Molecule Metabolic Process DUTP Catabolic Process Pyrimidine Nucleoside Biosynthetic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways
Drugs		Deoxyuridine-5\'-Diphosphate 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
Diseases
GWAS		Protein quantitative trait loci ( 18464913)
Protein-protein Interactions		9 interactors: CDK1 ESR1 ESRRA ESRRG NUDT18 PLEKHF2 PPARA PPARD SPATA2
Entrez ID		1854
HPRD ID		03165
Ensembl ID		ENSG00000128951
Uniprot IDs		H0YNW5 P33316
PDB IDs		1Q5H 1Q5U 2HQU 3ARA 3ARN 3EHW 4FDR 4FDS
Enriched GO Terms of Interacting Partners?		Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Cellular Response To Hormone Stimulus Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Organic Cyclic Compound Response To Hormone Response To Steroid Hormone Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Response To Lipid Positive Regulation Of Cellular Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Positive Regulation Of Transcription, DNA-templated Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Response To Activity Tissue Development Fatty Acid Transport Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Reproduction Regulation Of Glycolytic By Positive Regulation Of Transcription From RNA Polymerase II Promoter DGDP Catabolic Process DADP Catabolic Process GDP Catabolic Process Pronuclear Fusion Maternal Process Involved In Female Pregnancy Cellular Nitrogen Compound Metabolic Process Epithelial Cell Proliferation Positive Regulation Of Metabolic Process Single Organism Reproductive Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Heart Development Nitrogen Compound Metabolic Process RNA Biosynthetic Process Reproductive Process Negative Regulation Of Gene Expression Monocarboxylic Acid Transport
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