PLEKHF2 and RABAC1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLEKHF2	RABAC1
Gene Name		pleckstrin homology domain containing, family F (with FYVE domain) member 2	Rab acceptor 1 (prenylated)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane	Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Membrane Cell Junction
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding Protein C-terminus Binding Identical Protein Binding Proline-rich Region Binding
	Biological Process	Protein Transport
Pathways
Drugs
Diseases
GWAS		Radiation response ( 20923822)
Protein-Protein Interactions		52 interactors: ACY3 AIMP2 APP APPL1 BEND7 BLOC1S6 BSCL2 CCDC85B CEP44 CHIC2 DTX2 DUT FBXO28 FHL3 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NONO NPM2 PRKAR1A PRPSAP1 RABAC1 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SDPR SEPT2 SEPT6 SETBP1 SFN SPEF1 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z ZNF250 ZNF263 ZNF398	63 interactors: ADCK3 CMTM3 CREB3 DUSP12 FAM160A2 FXR2 GDI1 HRAS HRG LNX1 MAD2L1 MCF2L MIEF2 NAT14 NDRG4 NIF3L1 NR3C2 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP5 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RPS20 RRAS2 SGK1 SNCA SNX1 SNX10 SNX11 SNX15 SPG21 SYT16 TNIP1 TRIM32 TSHR TUBB2A TXN2 VAMP2 VIM VTA1 WDYHV1 WIPI2 ZFYVE21
Entrez ID		79666	10567
HPRD ID		15147	05375
Ensembl ID		ENSG00000175895	ENSG00000105404
Uniprot IDs		Q9H8W4	Q9UI14
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Cellular Metabolic Process	Ras Protein Signal Transduction Rab Protein Signal Transduction Small GTPase Mediated Signal Transduction Establishment Of Protein Localization Protein Transport Protein Localization Cellular Protein Localization Cellular Localization Intracellular Protein Transport Regulation Of Cellular Component Organization Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport Establishment Of Localization In Cell Intracellular Transport Intracellular Signal Transduction Endosomal Transport Regulation Of Exocytosis Transport Cellular Response To Stimulus Cell Communication Regulation Of Endocytosis Endocytosis Regulation Of Locomotion Vesicle Organization Endosome Organization Response To Stimulus Regulation Of Synaptic Vesicle Transport Regulation Of Cell Projection Organization Signaling Signal Transduction Cytoplasmic Transport Establishment Of Vesicle Localization Regulation Of Neuronal Synaptic Plasticity Vesicle Localization Regulation Of Organelle Organization Regulation Of Cell Migration Positive Regulation Of Metabolic Process Early Endosome To Late Endosome Transport Regulation Of Neurotransmitter Secretion Regulation Of Cell Motility Regulation Of Signaling Regulation Of Cellular Localization Regulation Of Cellular Component Movement Regulation Of Cellular Process Regulation Of Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Transport Synaptic Vesicle Recycling Endomembrane System Organization
Tagcloud ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering
Tagcloud (Difference) ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering
Tagcloud (Intersection) ?