PLEKHF2 and S100A13

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PLEKHF2	S100A13
Gene Name		pleckstrin homology domain containing, family F (with FYVE domain) member 2	S100 calcium binding protein A13
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane	Extracellular Space Nucleus Cytoplasm Cytosol Mast Cell Granule Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Metal Ion Binding	Copper Ion Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Lipid Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity RAGE Receptor Binding
	Biological Process	Protein Transport	Positive Regulation Of Cell Proliferation Regulation Of Cell Shape Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Mast Cell Degranulation Response To Copper Ion Cytokine Secretion Interleukin-1 Alpha Secretion Response To Electrical Stimulus
Pathways
Drugs			Olopatadine Amlexanox
Diseases
GWAS		Radiation response ( 20923822)
Protein-Protein Interactions		52 interactors: ACY3 AIMP2 APP APPL1 BEND7 BLOC1S6 BSCL2 CCDC85B CEP44 CHIC2 DTX2 DUT FBXO28 FHL3 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NONO NPM2 PRKAR1A PRPSAP1 RABAC1 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SDPR SEPT2 SEPT6 SETBP1 SFN SPEF1 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z ZNF250 ZNF263 ZNF398	7 interactors: FGF1 IGBP1 IL1A IRF9 PHYHIP PLEKHF2 SYT1
Entrez ID		79666	6284
HPRD ID		15147	03586
Ensembl ID		ENSG00000175895	ENSG00000189171
Uniprot IDs		Q9H8W4	Q99584
PDB IDs			1YUR 1YUS 1YUT 1YUU 2EGD 2H2K 2K8M 2KI4 2KI6 2KOT 2L5X 2LE9
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Cellular Metabolic Process	Cellular Response To Heat Branch Elongation Involved In Ureteric Bud Branching Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Response To Heat Regulation Of MAPK Cascade Positive Regulation Of Angiogenesis Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Cell Division Response To Cytokine Immune System Process Regulation Of Stress-activated MAPK Cascade Response To Temperature Stimulus Regulation Of ERK1 And ERK2 Cascade Fever Generation Calcium Ion-dependent Exocytosis Of Neurotransmitter Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Ureteric Bud Elongation Regulation Of Angiogenesis Negative Regulation Of Protein Dephosphorylation Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Substance Heat Generation Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Cell Division Wound Healing Involved In Inflammatory Response Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Cholesterol Metabolic Process Positive Regulation Of Secretion Response To Metal Ion Type I Interferon Biosynthetic Process Immune Response Regulation Of Phosphorylation Detection Of Calcium Ion Positive Regulation Of Transcription, DNA-templated Defense Response Regulation Of Signaling Ectopic Germ Cell Programmed Cell Death Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Microtubule-based Movement Signaling Positive Regulation Of Interleukin-2 Biosynthetic Process Cell Communication Type I Interferon Production Positive Regulation Of Organelle Organization Regulation Of Phosphorus Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Vesicle Fusion Positive Regulation Of Gene Expression Positive Regulation Of MAPK Cascade
Tagcloud ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering	anchor bilayer biophysical biphasic c2b calorimetry cu2 destabilized endothermic exothermic fgf1 isothermal itc lacks marginally mrc multiprotein nonclassical p40 phosphatidyl pockets proangiogenic ps synaptotagmin syt1 tb3 titration unilamellar vesicles
Tagcloud (Difference) ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering	anchor bilayer biophysical biphasic c2b calorimetry cu2 destabilized endothermic exothermic fgf1 isothermal itc lacks marginally mrc multiprotein nonclassical p40 phosphatidyl pockets proangiogenic ps synaptotagmin syt1 tb3 titration unilamellar vesicles
Tagcloud (Intersection) ?