PLEKHF2 and SDPR

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLEKHF2	SDPR
Gene Name		pleckstrin homology domain containing, family F (with FYVE domain) member 2	serum deprivation response
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane	Cytoplasm Cytosol Caveola
	Molecular Function	Protein Binding Metal Ion Binding	Phosphatidylserine Binding Protein Kinase C Binding Protein Binding Phospholipid Binding
	Biological Process	Protein Transport
Pathways
Drugs
Diseases
GWAS		Radiation response ( 20923822)
Protein-Protein Interactions		52 interactors: ACY3 AIMP2 APP APPL1 BEND7 BLOC1S6 BSCL2 CCDC85B CEP44 CHIC2 DTX2 DUT FBXO28 FHL3 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NONO NPM2 PRKAR1A PRPSAP1 RABAC1 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SDPR SEPT2 SEPT6 SETBP1 SFN SPEF1 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z ZNF250 ZNF263 ZNF398	4 interactors: A1CF NUDT18 PLEKHF2 PRKCA
Entrez ID		79666	8436
HPRD ID		15147	09470
Ensembl ID		ENSG00000175895	ENSG00000168497
Uniprot IDs		Q9H8W4	O95810
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Cellular Metabolic Process	GDP Catabolic Process DGDP Catabolic Process DADP Catabolic Process Positive Regulation Of Dense Core Granule Biogenesis Cytidine To Uridine Editing Histone H3-T6 Phosphorylation Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression Peptidyl-serine Autophosphorylation Base Conversion Or Substitution Editing Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Ribonucleoside Diphosphate Catabolic Process Nucleoside Diphosphate Catabolic Process Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Deoxyribonucleoside Diphosphate Metabolic Process Intracellular MRNA Localization Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Purine Ribonucleoside Catabolic Process Desmosome Organization Regulation Of Platelet Aggregation Negative Regulation Of Glucose Transport MRNA Modification Deoxyribose Phosphate Catabolic Process Induction Of Positive Chemotaxis Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Purine Ribonucleotide Catabolic Process Regulation Of Rhodopsin Mediated Signaling Pathway Deoxyribonucleotide Catabolic Process Negative Regulation Of CAMP Biosynthetic Process Activation Of Adenylate Cyclase Activity Regulation Of Cardiac Muscle Hypertrophy Rhodopsin Mediated Signaling Pathway Regulation Of Platelet Activation Positive Regulation Of Positive Chemotaxis Negative Regulation Of CAMP Metabolic Process Regulation Of The Force Of Heart Contraction Inactivation Of MAPK Activity Mitotic Nuclear Envelope Disassembly Positive Regulation Of Adenylate Cyclase Activity Purine Nucleotide Catabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Nucleotide Metabolic Process Histone Phosphorylation
Tagcloud ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering	8v2 bad bead chips corrected ctla4 error false fdr genespring humanref hybridized il8 illumina inflation ingenuity institutes ipa ly96 mrs paxgene prove rankin recovery stroke tlr2 tlr4 tubes validation
Tagcloud (Difference) ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering	8v2 bad bead chips corrected ctla4 error false fdr genespring humanref hybridized il8 illumina inflation ingenuity institutes ipa ly96 mrs paxgene prove rankin recovery stroke tlr2 tlr4 tubes validation
Tagcloud (Intersection) ?