PLEKHF2 and RTN1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLEKHF2	RTN1
Gene Name		pleckstrin homology domain containing, family F (with FYVE domain) member 2	reticulon 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane	Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Protein Transport	Neuron Differentiation
Pathways
Drugs
Diseases
GWAS		Radiation response ( 20923822)
Protein-Protein Interactions		52 interactors: ACY3 AIMP2 APP APPL1 BEND7 BLOC1S6 BSCL2 CCDC85B CEP44 CHIC2 DTX2 DUT FBXO28 FHL3 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NONO NPM2 PRKAR1A PRPSAP1 RABAC1 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SDPR SEPT2 SEPT6 SETBP1 SFN SPEF1 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z ZNF250 ZNF263 ZNF398	7 interactors: BCL2L1 FAM160A2 HDAC8 PLEKHF2 SDCBP SPAST UGCG
Entrez ID		79666	6252
HPRD ID		15147	02921
Ensembl ID		ENSG00000175895	ENSG00000139970
Uniprot IDs		Q9H8W4	A8K3B9 Q16799
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Cellular Metabolic Process	Regulation Of Organelle Organization Apoptotic Process In Bone Marrow Glucosylceramide Biosynthetic Process Cytokinesis Intracellular Transport Organelle Organization Cytokinesis, Completion Of Separation Mitotic Cell Cycle Positive Regulation Of Extracellular Vesicular Exosome Assembly Suppression By Virus Of Host Apoptotic Process Regulation Of Cohesin Localization To Chromatin Regulation Of Cellular Component Organization Positive Regulation Of Microtubule Depolymerization Glucosylceramide Metabolic Process Establishment Of Localization In Cell Cell Part Morphogenesis Regulation Of Extracellular Vesicular Exosome Assembly Response To Cycloheximide Cellular Process Regulating Host Cell Cycle In Response To Virus Mitotic Cytokinetic Process Protein Hexamerization Negative Regulation Of Execution Phase Of Apoptosis Regulation Of Cellular Localization Cell Cycle Process Cellular Localization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Substrate-dependent Cell Migration, Cell Extension Cellular Response To Virus Microtubule Severing Modulation By Virus Of Host Process Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Anoikis Cellular Response To Gamma Radiation Hepatocyte Apoptotic Process Regulation Of Sister Chromatid Cohesion Cell Cycle Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Anoikis Cell Separation After Cytokinesis Positive Regulation Of Protein Depolymerization Transport Positive Regulation Of Organelle Organization Protein Transport Early Endosome To Late Endosome Transport Negative Regulation Of Protein Localization To Plasma Membrane Cell Division Vesicle-mediated Transport Mitochondrion Morphogenesis Modulation By Virus Of Host Morphology Or Physiology
Tagcloud ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering	astrocyte clues constitute exert explore fi fl galactosidase glutathione homo immuno interacting library manf media mesencephalic neurotrophic proapoptotic pull regular reticular reticulons rtns sapiens screen speci transferase uorescence verified
Tagcloud (Difference) ?		abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting termination tethering	astrocyte clues constitute exert explore fi fl galactosidase glutathione homo immuno interacting library manf media mesencephalic neurotrophic proapoptotic pull regular reticular reticulons rtns sapiens speci transferase uorescence verified
Tagcloud (Intersection) ?		screen