DPEP1 and APPBP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DPEP1	APPBP2
Gene Name		dipeptidase 1 (renal)	amyloid beta precursor protein (cytoplasmic tail) binding protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Plasma Membrane Apical Plasma Membrane Cell Junction Anchored Component Of Membrane Microvillus Membrane Apical Part Of Cell Extracellular Vesicular Exosome	Nucleus Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane
	Molecular Function	Protein Binding Metalloexopeptidase Activity Dipeptidyl-peptidase Activity Zinc Ion Binding GPI Anchor Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metallodipeptidase Activity Modified Amino Acid Binding	Microtubule Motor Activity Protein Binding
	Biological Process	Proteolysis Leukotriene Metabolic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Antibiotic Metabolic Process Arachidonic Acid Metabolic Process Negative Regulation Of Cell Migration Cellular Response To Drug Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Small Molecule Metabolic Process Homocysteine Metabolic Process Cellular Response To Calcium Ion Cellular Response To Nitric Oxide Cellular Lactam Catabolic Process	Intracellular Protein Transport Metabolic Process Intracellular Transport
Pathways		Arachidonic acid metabolism Metabolism of lipids and lipoproteins Aflatoxin activation and detoxification Biological oxidations Synthesis of Leukotrienes (LT) and Eoxins (EX) Metabolic disorders of biological oxidation enzymes Defective ACY1 causes encephalopathy
Drugs		Cilastatin
Diseases
GWAS
Protein-Protein Interactions		2 interactors: APPBP2 KIAA1279	79 interactors: AHCY AIM2 AK3 ANKRD10 APP AR ARMCX5 C1orf50 C6orf226 CALM3 CCDC85C CCNL1 CDK16 CHMP5 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CTC1 DCD DHRS2 DPEP1 EID3 EPT1 ERO1L FAM19A4 FAM92A1 FSTL1 FXYD7 GALNT3 GCSAM GP9 GSTP1 HIPK4 HIST1H2AK HSPA4 KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MFSD3 MGC34796 MLLT3 MUL1 NFYA NPRL3 PCSK5 PI4KAP2 PPP1R8 PRKAA2 PRKACB PYROXD2 RASSF5 RNF128 RNF34 RRS1 SELV SLC22A6 SLC25A23 SNX5 ST8SIA5 SYNRG SYT11 TAF11 TBL3 TCF25 UBE2R2 UGGT2 WAS WDR24 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		1800	10513
HPRD ID		01563	05616
Ensembl ID		ENSG00000015413	ENSG00000062725
Uniprot IDs		P16444	Q92624
PDB IDs		1ITQ 1ITU
Enriched GO Terms of Interacting Partners?			Regulation Of Defense Response To Virus By Host Response To Stress Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Homocysteine Metabolic Process Cellular Response To Organic Substance
Tagcloud ?		3t3 5azadc ach3 aza choosing cpg demethylated demethylating demethylation deoxycytidine dnmt genic h3k9me3 igf2r kinds knock methylated minimally nih oct per1 reactivate regions repeats repetitive sall3 satellite silenced treating	10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Difference) ?		3t3 5azadc ach3 aza choosing cpg demethylated demethylating demethylation deoxycytidine dnmt genic h3k9me3 igf2r kinds knock methylated minimally nih oct per1 reactivate regions repeats repetitive sall3 satellite silenced treating	10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Intersection) ?