DPEP1 and KIAA1279

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		DPEP1	KIAA1279
Gene Name		dipeptidase 1 (renal)	KIAA1279
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Plasma Membrane Apical Plasma Membrane Cell Junction Anchored Component Of Membrane Microvillus Membrane Apical Part Of Cell Extracellular Vesicular Exosome	Mitochondrion Cytoskeleton
	Molecular Function	Protein Binding Metalloexopeptidase Activity Dipeptidyl-peptidase Activity Zinc Ion Binding GPI Anchor Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metallodipeptidase Activity Modified Amino Acid Binding	Protein Binding Kinesin Binding
	Biological Process	Proteolysis Leukotriene Metabolic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Antibiotic Metabolic Process Arachidonic Acid Metabolic Process Negative Regulation Of Cell Migration Cellular Response To Drug Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Small Molecule Metabolic Process Homocysteine Metabolic Process Cellular Response To Calcium Ion Cellular Response To Nitric Oxide Cellular Lactam Catabolic Process	Mitochondrial Transport Nervous System Development Cell Differentiation
Pathways		Arachidonic acid metabolism Metabolism of lipids and lipoproteins Aflatoxin activation and detoxification Biological oxidations Synthesis of Leukotrienes (LT) and Eoxins (EX) Metabolic disorders of biological oxidation enzymes Defective ACY1 causes encephalopathy
Drugs		Cilastatin
Diseases
GWAS
Protein-Protein Interactions		2 interactors: APPBP2 KIAA1279	10 interactors: ATXN2 CEP76 DOK2 DPEP1 HBP1 PLEKHF1 RGR TERF1 ZNF638 ZNF670
Entrez ID		1800	26128
HPRD ID		01563	13848
Ensembl ID		ENSG00000015413	ENSG00000198954
Uniprot IDs		P16444	Q96EK5
PDB IDs		1ITQ 1ITU
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Chylomicron Remnant Clearance Cellular Lactam Catabolic Process Antibiotic Metabolic Process Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Cellular Process G2/M Transition Of Mitotic Cell Cycle Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Microtubule Cytoskeleton Organization Telomere Maintenance Via Telomere Shortening Regulation Of Microtubule-based Process Regulation Of Metabolic Process Response To Heparin Negative Regulation Of Telomere Maintenance Via Telomerase Homocysteine Metabolic Process Replicative Cell Aging Negative Regulation Of Receptor Internalization Regulation Of Nuclear Cell Cycle DNA Replication Cytoplasmic MRNA Processing Body Assembly Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Centriole Replication Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Transcytosis Positive Regulation Of Microtubule Polymerization Cellular Response To Nitric Oxide Regulation Of Cell Cycle Cerebellar Purkinje Cell Differentiation Positive Regulation Of Lipoprotein Lipase Activity Protein-chromophore Linkage Heterocycle Metabolic Process Regulation Of Telomerase Activity Stress Granule Assembly Response To Nitric Oxide
Tagcloud ?		3t3 5azadc ach3 aza choosing cpg demethylated demethylating demethylation deoxycytidine dnmt genic h3k9me3 igf2r kinds knock methylated minimally nih oct per1 reactivate regions repeats repetitive sall3 satellite silenced treating	arfgef2 arx circonvolutions cobblestone col18a1 delection dieker emx2 filamin flna frontoparietal genetical glioneural gyri heterotopia laminations neuroradiological perisylvian polymicrogyria pseudobulbar rab3gap1 reln schizencephaly srpx2 subaracnoid sulci tbr2 tuba1a vldlr
Tagcloud (Difference) ?		3t3 5azadc ach3 aza choosing cpg demethylated demethylating demethylation deoxycytidine dnmt genic h3k9me3 igf2r kinds knock methylated minimally nih oct per1 reactivate regions repeats repetitive sall3 satellite silenced treating	arfgef2 arx circonvolutions cobblestone col18a1 delection dieker emx2 filamin flna frontoparietal genetical glioneural gyri heterotopia laminations neuroradiological perisylvian polymicrogyria pseudobulbar rab3gap1 reln schizencephaly srpx2 subaracnoid sulci tbr2 tuba1a vldlr
Tagcloud (Intersection) ?