ECH1 and CSTF2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ECH1	CSTF2
Gene Name		enoyl CoA hydratase 1, peroxisomal	cleavage stimulation factor, 3 pre-RNA, subunit 2, 64kDa
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Peroxisome Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Cleavage Body
	Molecular Function	Receptor Binding Protein Binding Isomerase Activity	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Fatty Acid Beta-oxidation	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage RNA Splicing Gene Expression MRNA 3'-end Processing
Pathways			mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: APP CSTF2 EEF1D EEF1G FAM9B HTT PAFAH1B3 PEX5 SERPINB9 STAT3 TIMP1 TLR10 TRAF1	23 interactors: APP BAG6 C14orf1 CHD3 CSTF3 DDX1 ECH1 EEF1G FEZ1 HGS IKBKAP IMMT KAT5 KIAA1377 POLR2A SPAG8 SS18L1 SUB1 SYMPK TFG UBQLN1 UBQLN4 ZNF341
Entrez ID		1891	1478
HPRD ID		02825	02652
Ensembl ID		ENSG00000104823	ENSG00000101811
Uniprot IDs		Q13011	E7EWR4 P33240
PDB IDs		2VRE	1P1T 2J8P
Enriched GO Terms of Interacting Partners?		Regulation Of Developmental Growth Regulation Of Multicellular Organism Growth Protein Import Central Nervous System Development MRNA Polyadenylation Response To Estrogen RNA Polyadenylation Regulation Of Growth Endoplasmic Reticulum Organization Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Axon Cargo Transport Mating Negative Regulation Of Neurogenesis Mitochondrial Membrane Organization Neuron Apoptotic Process Brain Development Visual Learning Sexual Reproduction Head Development Visual Behavior Neuron Death Neural Plate Formation Negative Regulation Of Cell Development Platelet Degranulation Regulation Of Cell Death Negative Regulation Of Proteolysis Establishment Of Protein Localization To Organelle Negative Regulation Of Protein Processing MRNA 3'-end Processing Associative Learning Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Response To Hormone Regulation Of Peptidase Activity Negative Regulation Of Protein Homotetramerization Synaptic Growth At Neuromuscular Junction Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Apoptotic Process Negative Regulation Of Cell Death Protein Targeting Feeding Behavior Programmed Cell Death Forebrain Development Regulation Of Signal Transduction RNA 3'-end Processing Reproduction Cell Death	MRNA Polyadenylation Gene Expression RNA Polyadenylation RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process MRNA Processing MRNA 3'-end Processing Regulation Of Protein Metabolic Process MRNA Metabolic Process RNA 3'-end Processing Regulation Of Gene Expression Regulation Of Metabolic Process RNA Processing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Chromosome Organization Regulation Of Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Transcription Elongation From RNA Polymerase II Promoter Transcription, RNA-templated Synaptic Growth At Neuromuscular Junction Nitrogen Compound Metabolic Process Regulation Of Dendrite Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Modification Regulation Of Epidermal Growth Factor Receptor Signaling Pathway DNA Duplex Unwinding DNA Geometric Change Regulation Of ERBB Signaling Pathway Collateral Sprouting In Absence Of Injury DNA-templated Transcription, Elongation Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process RNA Splicing Regulation Of Dendrite Development Collateral Sprouting Axon Midline Choice Point Recognition
Tagcloud ?		33k butylhydroperoxide choline coa disturbed enoyl galactosidase hayflick hmsc hmscs hydratase hyperoxia inducer metabolites mlc2 myosin p30 peroxisomal premature prosomal psma1 replicative senescence shares shortening sips spots sublethal tert
Tagcloud (Difference) ?		33k butylhydroperoxide choline coa disturbed enoyl galactosidase hayflick hmsc hmscs hydratase hyperoxia inducer metabolites mlc2 myosin p30 peroxisomal premature prosomal psma1 replicative senescence shares shortening sips spots sublethal tert
Tagcloud (Intersection) ?