ECH1

Description		enoyl-CoA hydratase 1
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Membrane Extracellular Exosome
	Molecular Function	Catalytic Activity Protein Binding Isomerase Activity Delta(3,5)-delta(2,4)-dienoyl-CoA Isomerase Activity
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation
Pathways		Peroxisomal protein import Peroxisomal protein import Mitochondrial protein degradation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		13 interacting genes: APP CSTF2 EEF1D EEF1G FAM9B FXR1 FXR2 HTT PAFAH1B3 SERPINB9 STAT3 TIMP1 TLR10
Entrez ID		1891
HPRD ID		02825
Ensembl ID		ENSG00000104823
Uniprot IDs		A0A384MR44 Q13011
PDB IDs		2VRE 8SK6
Enriched GO Terms of Interacting Partners?		Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Endopeptidase Activity Positive Regulation Of Catabolic Process Negative Regulation Of Long-term Synaptic Potentiation Peptidase Inhibitor Activity Translation Elongation Factor Activity Negative Regulation Of Peptidase Activity Regulation Of Endopeptidase Activity Positive Regulation Of MRNA Catabolic Process Translation Regulator Activity Protein Heterodimerization Activity Protein Homodimerization Activity Regulation Of Membrane Protein Ectodomain Proteolysis Positive Regulation Of MRNA Metabolic Process Regulation Of MiRNA-mediated Gene Silencing Dentate Gyrus Development Regulation Of Post-transcriptional Gene Silencing Regulation Of Defense Response Regulation Of Tumor Necrosis Factor Production Modulation Of Chemical Synaptic Transmission Positive Regulation Of ATP Metabolic Process Negative Regulation Of Hydrolase Activity Regulation Of MRNA Stability Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Synaptic Plasticity Regulation Of Long-term Synaptic Potentiation Cellular Response To Nerve Growth Factor Stimulus Regulation Of RNA Stability Response To Nerve Growth Factor Amyloid-beta Complex Presynapse Growth Cone Lamellipodium Postsynapse Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Calcium-mediated Signaling MRNA Binding Post-transcriptional Regulation Of Gene Expression Positive Regulation Of Interleukin-1 Beta Production Translational Elongation Regulation Of Carbohydrate Catabolic Process Platelet Alpha Granule Lumen Identical Protein Binding Heat Shock Protein Binding Regulation Of Multicellular Organism Growth
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