ECH1 and TLR10

Number of citations of the paper that reports this interaction (PMID 16482509)
13

Data Source:
HPRD (two hybrid)

		ECH1	TLR10
Gene Name		enoyl CoA hydratase 1, peroxisomal	toll-like receptor 10
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Peroxisome Membrane Extracellular Vesicular Exosome	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Receptor Binding Protein Binding Isomerase Activity	Transmembrane Signaling Receptor Activity
	Biological Process	Fatty Acid Beta-oxidation	Toll-like Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Inflammatory Response Immune Response Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Innate Immune Response Regulation Of Cytokine Secretion Positive Regulation Of Inflammatory Response
Pathways			Toll-Like Receptors Cascades Toll Like Receptor 10 (TLR10) Cascade MyD88 cascade initiated on plasma membrane Toll Like Receptor 5 (TLR5) Cascade Innate Immune System
Drugs
Diseases
GWAS			Helicobacter pylori serologic status ( 23652523)
Protein-Protein Interactions		13 interactors: APP CSTF2 EEF1D EEF1G FAM9B HTT PAFAH1B3 PEX5 SERPINB9 STAT3 TIMP1 TLR10 TRAF1	11 interactors: CAT ECH1 F8A1 FLNA FUT7 GLDC LUC7L3 MYD88 PTPN6 TLR1 TLR2
Entrez ID		1891	81793
HPRD ID		02825	05884
Ensembl ID		ENSG00000104823	ENSG00000174123
Uniprot IDs		Q13011	Q9BXR5
PDB IDs		2VRE	2J67
Enriched GO Terms of Interacting Partners?		Regulation Of Developmental Growth Regulation Of Multicellular Organism Growth Protein Import Central Nervous System Development MRNA Polyadenylation Response To Estrogen RNA Polyadenylation Regulation Of Growth Endoplasmic Reticulum Organization Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Axon Cargo Transport Mating Negative Regulation Of Neurogenesis Mitochondrial Membrane Organization Neuron Apoptotic Process Brain Development Visual Learning Sexual Reproduction Head Development Visual Behavior Neuron Death Neural Plate Formation Negative Regulation Of Cell Development Platelet Degranulation Regulation Of Cell Death Negative Regulation Of Proteolysis Establishment Of Protein Localization To Organelle Negative Regulation Of Protein Processing MRNA 3'-end Processing Associative Learning Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Response To Hormone Regulation Of Peptidase Activity Negative Regulation Of Protein Homotetramerization Synaptic Growth At Neuromuscular Junction Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Apoptotic Process Negative Regulation Of Cell Death Protein Targeting Feeding Behavior Programmed Cell Death Forebrain Development Regulation Of Signal Transduction RNA 3'-end Processing Reproduction Cell Death	Cellular Response To Triacyl Bacterial Lipopeptide Detection Of Triacyl Bacterial Lipopeptide Response To Molecule Of Fungal Origin Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Cytokine Biosynthetic Process Regulation Of Innate Immune Response Detection Of Bacterial Lipoprotein MyD88-dependent Toll-like Receptor Signaling Pathway Cell Activation Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Cellular Response To Bacterial Lipopeptide Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Interleukin-6 Production Response To Peptidoglycan Detection Of Molecule Of Bacterial Origin Toll-like Receptor Signaling Pathway Regulation Of Cytokine Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Tumor Necrosis Factor Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Detection Of Bacterium Immune Response-regulating Signaling Pathway Cellular Response To Molecule Of Bacterial Origin Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Growth Of Symbiont In Host Positive Regulation Of Innate Immune Response Detection Of Biotic Stimulus Macrophage Activation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Glycine Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Platelet Aggregation Positive Regulation Of Immune Response Positive Regulation Of Signal Transduction Positive Regulation Of Transcription Factor Import Into Nucleus Lipopolysaccharide-mediated Signaling Pathway Response To Fungus Immune Response Positive Regulation Of Chemokine Production Regulation Of Chemokine Production Serine Family Amino Acid Metabolic Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Innate Immune Response
Tagcloud ?		33k butylhydroperoxide choline coa disturbed enoyl galactosidase hayflick hmsc hmscs hydratase hyperoxia inducer metabolites mlc2 myosin p30 peroxisomal premature prosomal psma1 replicative senescence shares shortening sips spots sublethal tert	bewo broadly danger endosomal immunoassay initiating inter multiplex placental proper qpcr respond ten tlr2 tlr3 tlr4 tlr5 tlr6 tlr7 tlr8 tlr9 tlrs toll trimester trophoblast trophoblasts vegfa
Tagcloud (Difference) ?		33k butylhydroperoxide choline coa disturbed enoyl galactosidase hayflick hmsc hmscs hydratase hyperoxia inducer metabolites mlc2 myosin p30 peroxisomal premature prosomal psma1 replicative senescence shares shortening sips spots sublethal tert	bewo broadly danger endosomal immunoassay initiating inter multiplex placental proper qpcr respond ten tlr2 tlr3 tlr4 tlr5 tlr6 tlr7 tlr8 tlr9 tlrs toll trimester trophoblast trophoblasts vegfa
Tagcloud (Intersection) ?