ECH1 and SERPINB9

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ECH1	SERPINB9
Description		enoyl-CoA hydratase 1	serpin family B member 9
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Membrane Extracellular Exosome	Extracellular Space Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Membrane Extracellular Matrix Extracellular Exosome
	Molecular Function	Catalytic Activity Protein Binding Isomerase Activity Delta(3,5)-delta(2,4)-dienoyl-CoA Isomerase Activity	Protease Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation	Mast Cell Mediated Immunity Immune Response Negative Regulation Of Endopeptidase Activity Protection From Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Apoptotic Process Cellular Response To Estrogen Stimulus
Pathways		Peroxisomal protein import Peroxisomal protein import Mitochondrial protein degradation
Drugs			Raloxifene
Diseases
GWAS		Blood protein levels ( 30072576) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)	Left ventricular global circumferential strain ( 33495596) Plateletcrit ( 32888494) Vitiligo ( 27723757)
Interacting Genes		13 interacting genes: APP CSTF2 EEF1D EEF1G FAM9B FXR1 FXR2 HTT PAFAH1B3 SERPINB9 STAT3 TIMP1 TLR10	28 interacting genes: BRD7 CASP1 CASP4 CCDC90B COPS6 CRMP1 ECH1 EEF1A1 ERG28 GAPDH GBP2 GDF9 GZMB IGSF21 LRIF1 MED31 PLEKHM1 PRPF40A RBM48 SETDB1 TLE1 TP53 TRAF5 TUBB2A UBR1 UNC119 XRCC6 ZHX1
Entrez ID		1891	5272
HPRD ID		02825	03480
Ensembl ID		ENSG00000104823	ENSG00000170542
Uniprot IDs		A0A384MR44 Q13011	A0A024QZT4 P50453
PDB IDs		2VRE 8SK6	8ZCR
Enriched GO Terms of Interacting Partners?		Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Endopeptidase Activity Positive Regulation Of Catabolic Process Negative Regulation Of Long-term Synaptic Potentiation Peptidase Inhibitor Activity Translation Elongation Factor Activity Negative Regulation Of Peptidase Activity Regulation Of Endopeptidase Activity Positive Regulation Of MRNA Catabolic Process Translation Regulator Activity Protein Heterodimerization Activity Protein Homodimerization Activity Regulation Of Membrane Protein Ectodomain Proteolysis Positive Regulation Of MRNA Metabolic Process Regulation Of MiRNA-mediated Gene Silencing Dentate Gyrus Development Regulation Of Post-transcriptional Gene Silencing Regulation Of Defense Response Regulation Of Tumor Necrosis Factor Production Modulation Of Chemical Synaptic Transmission Positive Regulation Of ATP Metabolic Process Negative Regulation Of Hydrolase Activity Regulation Of MRNA Stability Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Synaptic Plasticity Regulation Of Long-term Synaptic Potentiation Cellular Response To Nerve Growth Factor Stimulus Regulation Of RNA Stability Response To Nerve Growth Factor Amyloid-beta Complex Presynapse Growth Cone Lamellipodium Postsynapse Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Calcium-mediated Signaling MRNA Binding Post-transcriptional Regulation Of Gene Expression Positive Regulation Of Interleukin-1 Beta Production Translational Elongation Regulation Of Carbohydrate Catabolic Process Platelet Alpha Granule Lumen Identical Protein Binding Heat Shock Protein Binding Regulation Of Multicellular Organism Growth	Pyroptotic Cell Death NLRP1 Inflammasome Complex Pyroptotic Inflammatory Response Nuclear Matrix Canonical Inflammasome Complex Response To Osmotic Stress Interleukin-18-mediated Signaling Pathway Cellular Response To Type II Interferon CARD Domain Binding Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
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