AFTPH and GGA2

Number of citations of the paper that reports this interaction (PMID 14665628)
21

Data Source:
HPRD (two hybrid)

		AFTPH	GGA2
Gene Name		aftiphilin	golgi-associated, gamma adaptin ear containing, ARF binding protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol AP-1 Adaptor Complex Intracellular Membrane-bounded Organelle	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin Adaptor Complex Clathrin-coated Vesicle
	Molecular Function	Clathrin Binding	Protein Binding ADP-ribosylation Factor Binding
	Biological Process	Protein Transport	Intracellular Protein Transport Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AP1G1 AP1G2 GGA1 GGA2 GGA3 LIG4 STAT5B UBE3A	30 interactors: AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC GGA1 GGA3 HGS HTT IGF2R LRP3 M6PR PIN1 RAB5A RABEP1 RABGEF1 RNF11 SORL1 SORT1 SPG21 STAB1 SYNRG TRIM23 VPS18
Entrez ID		54812	23062
HPRD ID		10635	09347
Ensembl ID		ENSG00000119844	ENSG00000103365
Uniprot IDs		Q53GW0 Q6ULP2	Q9UJY4
PDB IDs			1MHQ
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Intracellular Protein Transport Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Viral Process Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Cellular Protein Localization Positive Regulation Of Natural Killer Cell Activation Protein Transport Establishment Of Protein Localization Intracellular Transport Transport Protein Localization Establishment Of Localization In Cell Regulation Of Protein Catabolic Process T Cell Differentiation In Thymus Sperm Entry DNA Ligation Involved In DNA Recombination Cellular Localization Ovulation Cycle Process Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Female Gonad Development Ovulation Cycle Development Of Primary Female Sexual Characteristics Positive Regulation Of Natural Killer Cell Degranulation Golgi To Lysosome Transport T Cell Differentiation Creatinine Metabolic Process Development Of Secondary Male Sexual Characteristics Positive Regulation Of Innate Immune Response Isoleucine Metabolic Process Allantoin Metabolic Process Positive Regulation Of Natural Killer Cell Proliferation Lagging Strand Elongation Pro-B Cell Differentiation Positive Regulation Of Protein Catabolic Process Taurine Metabolic Process Regulation Of Natural Killer Cell Proliferation Prolactin Signaling Pathway Response To Interleukin-15 Golgi To Vacuole Transport Establishment Of Integrated Proviral Latency Gonad Development Development Of Primary Sexual Characteristics Lymphocyte Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Pigment Granule Maturation	Vesicle-mediated Transport Endocytosis Intracellular Transport Protein Transport Establishment Of Protein Localization Transport Establishment Of Localization In Cell Protein Localization Cellular Localization Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Lysosomal Transport Golgi Vesicle Transport Vacuolar Transport Cellular Protein Localization Endosomal Transport Regulation Of Vesicle-mediated Transport Endosome To Lysosome Transport Cytoplasmic Transport Visual Learning Membrane Organization Visual Behavior Protein Targeting To Lysosome Protein Localization To Lysosome Associative Learning Cellular Copper Ion Homeostasis Membrane Protein Ectodomain Proteolysis Signaling Protein Targeting To Vacuole Copper Ion Homeostasis Cell Communication Negative Regulation Of Signaling Establishment Of Protein Localization To Vacuole Learning Transition Metal Ion Homeostasis Membrane Protein Proteolysis Regulation Of Exocytosis Retrograde Vesicle-mediated Transport, Golgi To ER Regulation Of Synaptic Plasticity Regulation Of Protein Catabolic Process Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Phosphorylation Neural Plate Formation Negative Regulation Of Kit Signaling Pathway Positive Regulation Of Early Endosome To Recycling Endosome Transport Negative Regulation Of Tau-protein Kinase Activity Negative Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Choline O-acetyltransferase Activity
Tagcloud ?			addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true
Tagcloud (Difference) ?			addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true
Tagcloud (Intersection) ?