AFTPH and GGA1

Number of citations of the paper that reports this interaction (PMID 14665628)
21

Data Source:
HPRD (two hybrid)

		AFTPH	GGA1
Gene Name		aftiphilin	golgi-associated, gamma adaptin ear containing, ARF binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol AP-1 Adaptor Complex Intracellular Membrane-bounded Organelle	Nucleoplasm Golgi Apparatus Endosome Membrane Membrane Clathrin Adaptor Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Clathrin Binding	Molecular_function Protein Binding
	Biological Process	Protein Transport	Intracellular Protein Transport Vesicle-mediated Transport Positive Regulation Of Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AP1G1 AP1G2 GGA1 GGA2 GGA3 LIG4 STAT5B UBE3A	36 interactors: AFTPH AP1AR APP ARF1 ARF3 ARF5 ARF6 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CLINT1 CLTC CSNK2A1 DTNB F8 GGA2 GGA3 IGF2R LRP3 M6PR RAB5A RABEP1 RABGEF1 RNF11 RPS27A SMAD3 SORL1 SORT1 STAB1 SYNRG TSG101 UBC VPS18
Entrez ID		54812	26088
HPRD ID		10635	12078
Ensembl ID		ENSG00000119844	ENSG00000100083
Uniprot IDs		Q53GW0 Q6ULP2	Q6IC75 Q9UJY5
PDB IDs			1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Intracellular Protein Transport Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Viral Process Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Cellular Protein Localization Positive Regulation Of Natural Killer Cell Activation Protein Transport Establishment Of Protein Localization Intracellular Transport Transport Protein Localization Establishment Of Localization In Cell Regulation Of Protein Catabolic Process T Cell Differentiation In Thymus Sperm Entry DNA Ligation Involved In DNA Recombination Cellular Localization Ovulation Cycle Process Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Female Gonad Development Ovulation Cycle Development Of Primary Female Sexual Characteristics Positive Regulation Of Natural Killer Cell Degranulation Golgi To Lysosome Transport T Cell Differentiation Creatinine Metabolic Process Development Of Secondary Male Sexual Characteristics Positive Regulation Of Innate Immune Response Isoleucine Metabolic Process Allantoin Metabolic Process Positive Regulation Of Natural Killer Cell Proliferation Lagging Strand Elongation Pro-B Cell Differentiation Positive Regulation Of Protein Catabolic Process Taurine Metabolic Process Regulation Of Natural Killer Cell Proliferation Prolactin Signaling Pathway Response To Interleukin-15 Golgi To Vacuole Transport Establishment Of Integrated Proviral Latency Gonad Development Development Of Primary Sexual Characteristics Lymphocyte Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Pigment Granule Maturation	Vesicle-mediated Transport Transport Protein Transport Establishment Of Protein Localization Endocytosis Intracellular Transport Protein Localization Establishment Of Localization In Cell Cellular Localization Post-Golgi Vesicle-mediated Transport Endosomal Transport Viral Protein Processing Receptor-mediated Endocytosis Regulation Of Vesicle-mediated Transport Protein Processing Regulation Of Cellular Component Organization Cellular Protein Localization Golgi Vesicle Transport Negative Regulation Of Protein Metabolic Process Intracellular Protein Transport Virion Assembly Apoptotic Process Programmed Cell Death Intracellular Transport Of Virus Cell Death Death Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Protein Catabolic Process Regulation Of Cell Cycle Phase Transition Membrane Organization Regulation Of Mitotic Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Proteolysis Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Lysosomal Transport Positive Regulation Of Proteolysis Positive Regulation Of Wnt Signaling Pathway Regulation Of Cellular Localization Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Viral Process Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Growth Regulation Of Endocytosis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Viral Life Cycle Positive Regulation Of Cell Cycle Arrest
Tagcloud ?			adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically rabep1 reach sense tgn traffic trafficking transmembrane tubular whereby
Tagcloud (Difference) ?			adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically rabep1 reach sense tgn traffic trafficking transmembrane tubular whereby
Tagcloud (Intersection) ?