AFTPH and AP1G2

Number of citations of the paper that reports this interaction (PMID 14665628)
21

Data Source:
HPRD (two hybrid)

		AFTPH	AP1G2
Gene Name		aftiphilin	adaptor-related protein complex 1, gamma 2 subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol AP-1 Adaptor Complex Intracellular Membrane-bounded Organelle	Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Membrane AP-1 Adaptor Complex Transport Vesicle
	Molecular Function	Clathrin Binding	Protein Binding Protein Transporter Activity
	Biological Process	Protein Transport	Intracellular Protein Transport Viral Process Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS			Sudden cardiac arrest ( 21658281)
Protein-Protein Interactions		8 interactors: AP1G1 AP1G2 GGA1 GGA2 GGA3 LIG4 STAT5B UBE3A	12 interactors: AFTPH AP1S1 AP1S2 ATXN1L CENPK KDM1A NEDD4 PRMT6 RAB5A RABEP1 SYNRG XRN1
Entrez ID		54812	8906
HPRD ID		10635	04638
Ensembl ID		ENSG00000119844	ENSG00000213983
Uniprot IDs		Q53GW0 Q6ULP2	O75843 Q86V28
PDB IDs			2E9G 2YMT 3ZHF 4BCX
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Intracellular Protein Transport Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Viral Process Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Cellular Protein Localization Positive Regulation Of Natural Killer Cell Activation Protein Transport Establishment Of Protein Localization Intracellular Transport Transport Protein Localization Establishment Of Localization In Cell Regulation Of Protein Catabolic Process T Cell Differentiation In Thymus Sperm Entry DNA Ligation Involved In DNA Recombination Cellular Localization Ovulation Cycle Process Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Female Gonad Development Ovulation Cycle Development Of Primary Female Sexual Characteristics Positive Regulation Of Natural Killer Cell Degranulation Golgi To Lysosome Transport T Cell Differentiation Creatinine Metabolic Process Development Of Secondary Male Sexual Characteristics Positive Regulation Of Innate Immune Response Isoleucine Metabolic Process Allantoin Metabolic Process Positive Regulation Of Natural Killer Cell Proliferation Lagging Strand Elongation Pro-B Cell Differentiation Positive Regulation Of Protein Catabolic Process Taurine Metabolic Process Regulation Of Natural Killer Cell Proliferation Prolactin Signaling Pathway Response To Interleukin-15 Golgi To Vacuole Transport Establishment Of Integrated Proviral Latency Gonad Development Development Of Primary Sexual Characteristics Lymphocyte Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Pigment Granule Maturation	Protein Transport Establishment Of Protein Localization Endocytosis Protein Localization Vesicle-mediated Transport Intracellular Protein Transport Regulation Of Defense Response To Virus By Virus Viral Process Receptor Internalization Cellular Protein Localization Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Regulation Of Primitive Erythrocyte Differentiation Development Involved In Symbiotic Interaction Intracellular Transport Positive Regulation Of Stem Cell Proliferation Receptor-mediated Endocytosis Receptor Metabolic Process Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Histone H3-R2 Methylation Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Stem Cell Proliferation Receptor Internalization Involved In Canonical Wnt Signaling Pathway Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Endosome Size Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Establishment Of Localization In Cell Progesterone Receptor Signaling Pathway Chromatin Modification Regulation Of Immune System Process Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Nuclear MRNA Surveillance Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Biosynthetic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Glucocorticoid Receptor Signaling Pathway RNA Surveillance Cellular Localization Histone MRNA Catabolic Process Chromatin Organization Transport Positive Regulation Of Megakaryocyte Differentiation
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