AFTPH and AP1G2

Number of citations of the paper that reports this interaction (PubMedID 14665628)
0

Data Source:
HPRD (two hybrid)

		AFTPH	AP1G2
Description		aftiphilin	adaptor related protein complex 1 subunit gamma 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm	Golgi Membrane Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Membrane Membrane Coat AP-1 Adaptor Complex Transport Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Synapse Intracellular Vesicle
	Molecular Function	Protein Binding Clathrin Binding	Protein Binding Clathrin Adaptor Activity
	Biological Process	Protein Transport Intracellular Transport	Intracellular Protein Transport Golgi To Vacuole Transport Protein Transport Vesicle-mediated Transport
Pathways			Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS		Delirium ( 29631748) Lung adenocarcinoma ( 31326317) Metabolite levels ( 23823483)	Blood protein levels ( 30072576) Sudden cardiac arrest ( 21658281)
Interacting Genes		11 interacting genes: AP1G1 AP1G2 CLTC GGA1 GGA2 GGA3 LIG4 MAP1LC3B PEX14 STAT5B UBE3A	13 interacting genes: AFTPH AP1S1 AP1S2 ATXN1L CENPK DANCR KDM1A NEDD4 PRMT6 RABEP1 SNCA SYNRG XRN1
Entrez ID		54812	8906
HPRD ID		10635	04638
Ensembl ID		ENSG00000119844	ENSG00000213983
Uniprot IDs		A0A8Q3SI61 A0A8Q3SIA4 A0A8Q3WKU6 A0A8Q3WM48 Q53GW0 Q6ULP2	O75843 Q86U03 Q86V28
PDB IDs			2E9G 2YMT 3ZHF 4BCX
Enriched GO Terms of Interacting Partners?		Post-Golgi Vesicle-mediated Transport Intracellular Protein Transport Trans-Golgi Network Golgi Vesicle Transport Protein Localization To Cell Surface Protein Transport Golgi To Plasma Membrane Protein Transport Vesicle-mediated Transport Intracellular Transport Establishment Of Protein Localization Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Cellular Localization Establishment Of Localization In Cell Clathrin-coated Vesicle Small GTPase Binding Endosome Membrane AP-1 Adaptor Complex Intracellular Protein Localization Ubiquitin Binding Phosphatidylinositol Binding Clathrin Adaptor Activity Endosome Golgi To Vacuole Transport Cytosolic Transport Intracellular Vesicle Vesicle-mediated Transport To The Plasma Membrane Protein-containing Complex Disassembly Vacuolar Transport Membrane Coat Cytoplasmic Vesicle Membrane Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Protein Localization To Plasma Membrane Positive Regulation Of Natural Killer Cell Mediated Immunity Early Endosome Membrane Establishment Of Protein Localization To Membrane T Cell Differentiation In Thymus Protein Localization To Cell Periphery Regulation Of Natural Killer Cell Mediated Cytotoxicity Endosomal Transport Regulation Of Natural Killer Cell Mediated Immunity Establishment Of Integrated Proviral Latency Peroxisome Transport Along Microtubule Sperm Entry Positive Regulation Of Golgi Lumen Acidification Positive Regulation Of Leukocyte Mediated Cytotoxicity Golgi Apparatus Positive Regulation Of Cell Killing Protein Localization To Membrane Clathrin-coated Pit	AP-1 Adaptor Complex Endocytosis Clathrin Adaptor Activity Trans-Golgi Network Membrane Protein Transport Import Into Cell Melanosome Assembly Vesicle-mediated Transport Platelet Dense Granule Organization Establishment Of Protein Localization Membrane Coat Cytoplasmic Vesicle Receptor-mediated Endocytosis Cytoplasmic Vesicle Membrane Cellular Localization Terminal Bouton Melanosome Organization Establishment Of Localization In Cell Intracellular Protein Transport Pigment Granule Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Domain Specific Binding Negative Regulation Of Transcription By RNA Polymerase II Formation Of Structure Involved In A Symbiotic Process Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Stem Cell Proliferation Cellular Response To Puromycin Cellular Response To Cycloheximide Histone H2AR3 Methyltransferase Activity Intracellular Protein Localization Secretory Granule Organization Intracellular Transport Clathrin-coated Pit Receptor Internalization Channel Inhibitor Activity Perinuclear Region Of Cytoplasm Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Clathrin-coated Vesicle Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Histone H3R2 Methyltransferase Activity Early Endosome Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process
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