ARF1 and PLIN2

Number of citations of the paper that reports this interaction (PMID 15336557)
14

Data Source:
HPRD (in vitro, two hybrid)

		ARF1	PLIN2
Gene Name		ADP-ribosylation factor 1	perilipin 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytosol Plasma Membrane Focal Adhesion Postsynaptic Density Sarcomere Neuron Projection Postsynaptic Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Extracellular Region Nucleus Endoplasmic Reticulum Lipid Particle Cytosol Plasma Membrane
	Molecular Function	GTPase Activity Receptor Signaling Protein Activity Protein Binding GTP Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Receptor Internalization Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Cellular Copper Ion Homeostasis Retrograde Vesicle-mediated Transport, Golgi To ER Post-Golgi Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Protein Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Arp2/3 Complex-mediated Actin Nucleation Small Molecule Metabolic Process COPI Coating Of Golgi Vesicle Regulation Of Defense Response To Virus By Virus Long Term Synaptic Depression Membrane Organization Dendritic Spine Organization	Response To Organic Cyclic Compound Long-chain Fatty Acid Transport Lipid Storage Response To Drug Cellular Lipid Metabolic Process Small Molecule Metabolic Process
Pathways		Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Golgi Associated Vesicle Biogenesis Host Interactions of HIV factors The role of Nef in HIV-1 replication and disease pathogenesis Clathrin derived vesicle budding Lysosome Vesicle Biogenesis Golgi to ER Retrograde Transport MHC class II antigen presentation COPI Mediated Transport Phospholipid metabolism trans-Golgi Network Vesicle Budding Nef Mediated CD4 Down-regulation Adaptive Immune System PI Metabolism	PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: AP1B1 AP1G1 AP3B1 AP3D1 AP3S2 AP4E1 AP4M1 ARFGAP1 ARFIP1 ARFIP2 ARHGAP21 ASAP1 ASAP2 CHRM3 COPB1 COPE COPG1 CYTH1 CYTH2 EEF1G GGA1 GGA2 GGA3 GOSR2 INSR KDELR1 MDM4 NOA1 NPM1 PICK1 PIP5K1A PLD1 PLD2 PLEKHA8 PLIN2 RALA TMED10 TMED2 TMEM106A WBP11	3 interactors: ABHD5 ARF1 MAPK10
Entrez ID		375	123
HPRD ID		00054	00057
Ensembl ID		ENSG00000143761	ENSG00000147872
Uniprot IDs		P84077	Q6FHZ7 Q99541
PDB IDs		1HUR 1RE0 1U81 3O47 4HMY
Enriched GO Terms of Interacting Partners?		Intracellular Protein Transport Intracellular Transport Establishment Of Localization In Cell Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Cellular Localization Cellular Protein Localization Protein Localization COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Golgi Vesicle Transport Localization Within Membrane Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Transport Establishment Of Organelle Localization Vesicle Targeting, To, From Or Within Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Organelle Localization Vesicle Targeting Membrane Organization Membrane Budding Organelle Organization Regulation Of ARF Protein Signal Transduction Cytoplasmic Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport ER To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity Synaptic Vesicle Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Establishment Of Golgi Localization Golgi To Vacuole Transport Regulation Of Ras Protein Signal Transduction Endosome To Melanosome Transport Cargo Loading Into Vesicle Pigment Granule Maturation Axon Cargo Transport Intra-Golgi Vesicle-mediated Transport Cellular Pigment Accumulation Cellular Pigmentation	Glycerophospholipid Biosynthetic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Negative Regulation Of Sequestering Of Triglyceride JUN Phosphorylation Glycerolipid Metabolic Process Phospholipid Metabolic Process Positive Regulation Of Triglyceride Catabolic Process Positive Regulation Of Lipoprotein Lipase Activity COPI Coating Of Golgi Vesicle COPI-coated Vesicle Budding Lipid Biosynthetic Process Golgi Vesicle Budding Phosphate-containing Compound Metabolic Process Negative Regulation Of Lipid Storage Long Term Synaptic Depression Cellular Copper Ion Homeostasis Regulation Of Arp2/3 Complex-mediated Actin Nucleation Triglyceride Catabolic Process Dendritic Spine Organization Copper Ion Homeostasis Regulation Of Actin Nucleation Positive Regulation Of Lipid Catabolic Process Regulation Of Defense Response To Virus By Virus Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Acylglycerol Catabolic Process Vesicle Targeting, To, From Or Within Golgi Regulation Of Receptor Internalization Regulation Of Triglyceride Metabolic Process Retrograde Vesicle-mediated Transport, Golgi To ER Cellular Lipid Metabolic Process Localization Within Membrane Vesicle Targeting Organophosphate Metabolic Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Regulation Of Lipid Catabolic Process Regulation Of Lipid Storage Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Synaptic Transmission MyD88-independent Toll-like Receptor Signaling Pathway Lipid Metabolic Process Toll-like Receptor 3 Signaling Pathway Regulation Of Immune System Process MyD88-dependent Toll-like Receptor Signaling Pathway
Tagcloud ?		adp bulk close coated coatomer consumed contact copi dynamics endoplasmic exchange explored fission golgi governed gtpase interconnected maintain maintenance mitochondria mitochondrial powerhouse presumably produce proximity reticulum ribosylation thought vesicles	accumulate adipose aging atrogin atrophy characterizing decorated disuse donors droplets etiology hd imtg inactivity infiltration lateralis llmi mobility murf1 muscle muscular perilipins phenomenon plin5 plins sarcopenia strength triglycerides vastus
Tagcloud (Difference) ?		adp bulk close coated coatomer consumed contact copi dynamics endoplasmic exchange explored fission golgi governed gtpase interconnected maintain maintenance mitochondria mitochondrial powerhouse presumably produce proximity reticulum ribosylation thought vesicles	accumulate adipose aging atrogin atrophy characterizing decorated disuse donors droplets etiology hd imtg inactivity infiltration lateralis llmi mobility murf1 muscle muscular perilipins phenomenon plin5 plins sarcopenia strength triglycerides vastus
Tagcloud (Intersection) ?