ZMAT2 and TRIM37

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZMAT2	TRIM37
Gene Name		zinc finger, matrin-type 2	tripartite motif containing 37
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytoplasm Peroxisome Cytosol Aggresome ESC/E(Z) Complex Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Chromatin Binding Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process		Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of NF-kappaB Transcription Factor Activity Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination Negative Regulation Of Centriole Replication Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Aggresome Assembly
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Testicular germ cell tumor ( 23666239)
Protein-Protein Interactions		25 interactors: AK8 AMH CCDC57 CEP76 FSD2 FXR2 GOLGA2 HMBOX1 IKZF1 KRT40 LZTS2 MEOX2 MTUS2 PHC2 SPAG5 SPERT SSX2IP TFEC TFIP11 TRAF2 TRIM36 TRIM37 VPS52 ZBTB14 ZBTB8A	59 interactors: ANKRD11 APEX2 APTX ARNT2 BYSL CCDC33 CDC20B CDK5RAP2 COPB1 CWF19L2 DDX6 DLGAP5 EWSR1 FAM107A FAM124B FAM161A FAM50B FXR2 KAT5 KIAA0408 KIF9 LTBR MAGEB18 MCM10 MCRS1 NGFR NUDT18 PBK PNKP PRC1 RASD1 RHPN1 RIBC2 RPL9 SCNM1 SSX2IP TANK TCEB3B TNFRSF1B TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 UBASH3A UBB UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2U ZMAT2 ZNF329 ZNF417 ZNF655
Entrez ID		153527	4591
HPRD ID		08094	05463
Ensembl ID		ENSG00000146007	ENSG00000108395
Uniprot IDs		Q96NC0	A8K0V9 A8K8U4 F8WEE6 O94972
PDB IDs			3LRQ
Enriched GO Terms of Interacting Partners?		Regulation Of Centriole Replication Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Protein Autoubiquitination Negative Regulation Of Biosynthetic Process Regulation Of Centrosome Duplication Regulation Of Gene Expression Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Centrosome Cycle Positive Regulation Of Neutrophil Differentiation Spliceosomal Complex Disassembly Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Preantral Ovarian Follicle Growth Embryonic Ectodermal Digestive Tract Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Histone H2A-K119 Monoubiquitination Mitotic Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Cell Cycle Negative Regulation Of Centriole Replication Intraciliary Transport Involved In Cilium Morphogenesis Somite Specification Ectodermal Cell Differentiation Spindle Organization Regulation Of Cellular Process Microtubule Cytoskeleton Organization Oogenesis Stage Positive Regulation Of NK T Cell Differentiation Negative Regulation Of Glial Cell Apoptotic Process Negative Regulation Of Cellular Metabolic Process Gonadal Mesoderm Development Mullerian Duct Regression Mesoderm Development Regulation Of Protein Binding Positive Regulation Of Granulocyte Differentiation Regulation Of Cytoskeleton Organization Organ Development	Protein Polyubiquitination TRIF-dependent Toll-like Receptor Signaling Pathway Protein K48-linked Ubiquitination MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Protein Ubiquitination Protein Modification By Small Protein Conjugation Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Cellular Macromolecule Catabolic Process Regulation Of Innate Immune Response Protein K11-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein K63-linked Ubiquitination Cellular Response To Stress Catabolic Process Polynucleotide 3' Dephosphorylation Apoptotic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Protein Catabolic Process Immune Response-regulating Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of DNA-templated Transcription In Response To Stress Programmed Cell Death I-kappaB Kinase/NF-kappaB Signaling Regulation Of Mitotic Cell Cycle Phase Transition Cellular Response To DNA Damage Stimulus Regulation Of Cell Cycle Phase Transition Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Cell Death Death Activation Of NF-kappaB-inducing Kinase Activity Modification-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of NIK/NF-kappaB Signaling Cellular Protein Catabolic Process DNA Repair Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Proteolysis Regulation Of Stress-activated MAPK Cascade NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Regulation Of Metabolic Process
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