MAP2K6 and SMAD7

  • Number of citations of the paper that reports this interaction (PMID 12589052)
  • 49
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

MAP2K6

SMAD7

Gene Name mitogen-activated protein kinase kinase 6 SMAD family member 7
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225)
Protein-Protein Interactions 21 interactors: DCTN1 LRRK2 MAP2K4 MAP3K4 MAP3K5 MAP3K7 MAPK1 MAPK12 MAPK13 MAPK14 MAPKAPK2 MLH1 PKN1 PLCB2 RELA SMAD7 STAT4 TAOK2 TLR3 TRAF6 ZAK 54 interactors: ACVR1B AKT1 ASH1L AXIN1 BMPR1B CTNNB1 CXXC5 DVL1 EP300 ERBB2IP HAT1 HEYL KDM2A MAP2K3 MAP2K6 MAP3K7 MAPK14 MBD1 MKL2 MYOD1 NEDD4L PARD3 PARD3B PIAS1 PIAS4 RNF111 SASH3 SIRT1 SMAD2 SMAD4 SMAD6 SMURF1 SMURF2 SOX13 SOX5 SOX7 STAMBP STAMBPL1 STRAP TAB1 TGFB1I1 TGFBR1 TGFBR2 TTF1 TTF2 UBE2L3 UCHL5 WWP2 XRCC6 YAP1 ZBTB11 ZBTB44 ZEB1 ZNF107
Entrez ID 5608 4092
HPRD ID 03155 04241
Ensembl ID ENSG00000101665
Uniprot IDs A8K3Y2 P52564 B3KYA8 O15105
PDB IDs 2Y8O 3ENM 3FME 3VN9 2DJY 2KXQ 2LTV 2LTW 2LTX 2LTY 2LTZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
camk1  centriole  dkk1  enah  endosome  geo  gpsm2  inference  kcnq3  kpna2  lcn2  lef1  lysosome  multivesicular  nkx2  nr5a1  nup62  ontology  phosphoinositide  sfrp4  slc4a3  sort1  sstr5  stx1a  subnetwork  tbl3  transport  tshb  ube2c 
adp  beta1  blocks  decapentaplegic  deoxynucleotidyl  deoxyuridine  fibroblasts  fibrogenic  fibrotic  homolog  hydroxyproline  immunocytochemistry  mothers  myofibroblasts  nick  pd  peyronie  pretreated  quashed  ribose  smad2  smad3  terminate  tgf  transdifferentiation  transferase  transforming  triphosphate 
Tagcloud (Difference) ?
camk1  centriole  dkk1  enah  endosome  geo  gpsm2  inference  kcnq3  kpna2  lcn2  lef1  lysosome  multivesicular  nkx2  nr5a1  nup62  ontology  phosphoinositide  sfrp4  slc4a3  sort1  sstr5  stx1a  subnetwork  tbl3  transport  tshb  ube2c 
adp  beta1  blocks  decapentaplegic  deoxynucleotidyl  deoxyuridine  fibroblasts  fibrogenic  fibrotic  homolog  hydroxyproline  immunocytochemistry  mothers  myofibroblasts  nick  pd  peyronie  pretreated  quashed  ribose  smad2  smad3  terminate  tgf  transdifferentiation  transferase  transforming  triphosphate 
Tagcloud (Intersection) ?