ADD1 and ZDHHC17

Number of citations of the paper that reports this interaction (PMID 24705354)
0

Data Source:
BioGRID (two hybrid)

		ADD1	ZDHHC17
Gene Name		adducin 1 (alpha)	zinc finger, DHHC-type containing 17
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane Focal Adhesion F-actin Capping Protein Complex Postsynaptic Density Dendritic Spine Intermediate Filament Cytoskeleton Perinuclear Region Of Cytoplasm	Golgi Membrane Cytoplasm Golgi Apparatus Integral Component Of Membrane Golgi-associated Vesicle Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Actin Binding Structural Molecule Activity Calmodulin Binding Transcription Factor Binding Spectrin Binding T Cell Receptor Binding Protein Homodimerization Activity Poly(A) RNA Binding Protein Heterodimerization Activity Actin Filament Binding	Signal Transducer Activity Protein Binding Zinc Ion Binding Magnesium Ion Transmembrane Transporter Activity Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Identical Protein Binding
	Biological Process	Cell Morphogenesis In Utero Embryonic Development Cell Volume Homeostasis Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Hemoglobin Metabolic Process Actin Cytoskeleton Organization Erythrocyte Differentiation Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Protein Binding Multicellular Organism Growth Cellular Protein Metabolic Process Positive Regulation Of Angiogenesis Positive Regulation Of Endocytosis Homeostasis Of Number Of Cells Within A Tissue Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Cellular Response To Retinoic Acid	Signal Transduction Magnesium Ion Transport Protein Palmitoylation Lipoprotein Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Apoptotic cleavage of cellular proteins IRE1alpha activates chaperones Programmed Cell Death Apoptotic execution phase Caspase-mediated cleavage of cytoskeletal proteins XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: ADD2 ATP1A1 CALM1 CASP3 CSNK2B GEMIN7 HMG20A HSPH1 ID2 ID3 MAP1LC3B PRKACA PRKCD RFX1 ROCK1 SMARCC1 SPTA1 SPTAN1 SPTB TK1 ZDHHC17	191 interactors: ABCG4 ACTR1B ADD1 AHDC1 AIDA AK3 ALKBH3 ANKRD50 ANXA11 APBB1IP ARFGAP3 ASF1A ASIC4 BCAS3 BEX2 BTF3 C1orf216 C20orf141 CBS CCDC120 CCNE2 CDSN CENPBD1P1 CHMP1A CIB1 CLRN3 CNDP2 CNKSR1 COG3 CSTA CTCFL CTHRC1 DALRD3 DIXDC1 DLG4 DLK1 DR1 DTX3 E2F8 EDRF1 EEF1G ERCC6L EVL EXOSC9 EYA3 FAM122C FAM135B FAM207A FAM9A FBXO18 FOXD4L6 FTL FUT2 FUT9 GABPB1 GABPB2 GATA1 GOLPH3L GPR135 GRB10 GUSBP3 HBG1 HECTD3 HIST1H2BH HIST1H3H HLA-A HLA-DRB1 HMBS HOXA3 HS1BP3 HTT HYPM IFT20 IFT57 INPP5D JMJD7-PLA2G4B KIAA0141 KIAA0226L KIAA0408 KIAA0907 KNSTRN KRAS KRT17 KRT8P12 KRTAP11-1 KRTAP9-2 LCA5L LGALS9C LIN28A LMAN2L LOC401296 LOC554206 LRRC45 LY6G6C MANF MAP3K19 MIIP MLH3 MRFAP1 MRFAP1L1 MSANTD3 MSRB2 MYBPHL MYOZ2 NCBP1 NEBL NFATC2IP NFYC NIFK NPFF OBFC1 ODF2 OFCC1 OTUD7B OTX2 PBRM1 PDZK1IP1 PHF5A PLEKHB1 PPP1R21 PPTC7 PRMT5 PTMA QRICH1 RAB39B RAD51 RANGRF RAP1B RBM5 RCAN3 RIC8A RNF20 RNF38 RSBN1L SCNM1 SEMA4G SF3A3 SHOX2 SKA3 SLC1A3 SLC25A31 SLC9A9 SMARCB1 SNAP25 SOX14 SP2 SPRED2 SPRY4 SREBF2 SRSF4 STK25 SUMF2 SYT1 TAF8 TEAD1 THAP7 TIGD1 TMC6 TMCC1 TMEM115 TMEM186 TMTC1 TNFAIP1 TNFSF10 TOX TPGS2 TTC23 TTLL7 TXNDC12 TXNDC15 UBAC1 UBE2K USP18 USP32 VSX2 WAC WDR20 YIF1A YTHDF3 ZCCHC17 ZCCHC6 ZFC3H1 ZFP2 ZFP36 ZFYVE19 ZNF333 ZNF341 ZNF597 ZNF624 ZNF667-AS1 ZSCAN9
Entrez ID		118	23390
HPRD ID		00036	09697
Ensembl ID		ENSG00000087274	ENSG00000186908
Uniprot IDs		A2A3N8 P35611 Q86XM2	Q8IUH5
PDB IDs			3EU9
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Actin Filament Polymerization Response To External Stimulus Negative Regulation Of Protein Polymerization Regulation Of Actin Filament-based Process Regulation Of Binding Nervous System Development Negative Regulation Of Protein Complex Assembly Actin Filament Capping Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Negative Regulation Of Actin Filament Depolymerization Negative Regulation Of Cytoskeleton Organization Regulation Of Actin Filament Polymerization Regulation Of Actin Filament Depolymerization Execution Phase Of Apoptosis Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length System Development Negative Regulation Of Protein Complex Disassembly Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Stimulus Regulation Of Cell Activation Regulation Of Protein Depolymerization Neuron Differentiation Generation Of Neurons Developmental Process Regulation Of Cytoskeleton Organization Regulation Of Protein Complex Disassembly Multicellular Organismal Development Immune System Process Neurogenesis Anatomical Structure Development Cellular Metabolic Process Regulation Of Protein Binding Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Chemotaxis Regulation Of Cell Adhesion Activation Of Phospholipase C Activity Anatomical Structure Morphogenesis Regulation Of Cell-cell Adhesion Positive Regulation Of Phospholipase C Activity Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Cell Morphogenesis Involved In Differentiation Negative Regulation Of Glial Cell Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Regulation Of Cardiac Muscle Contraction Neurotrophin Signaling Pathway Positive Regulation Of Phospholipase Activity	Regulation Of Metabolic Process Transcription, DNA-templated RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Heterocycle Metabolic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Biosynthetic Process Cellular Process Organelle Organization Positive Regulation Of Metabolic Process Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Multicellular Organismal Development Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Chromosome Organization Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Neurotransmitter Uptake Developmental Process Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Golgi Organization Anatomical Structure Development Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Organelle Organization Positive Regulation Of Transcription, DNA-templated Chromatin Organization Cellular Component Assembly Regulation Of Gene Silencing Gene Silencing RNA 3'-end Processing Embryo Development Visual Learning Regulation Of Cell Projection Organization Visual Behavior RNA Processing
Tagcloud ?		arnt2 asked camk2g cstb ctgf downregulated dr1 epas1 globin gna11 hif1a hypoxic il6st khsrp mars multitude neuroglobin neuroprotection ngb o4 ogd pea15 r4 reoxygenation rest spatially temporally tg wt	1b atr atxn3 bcl11b cdkn1a cep290 cxcl5 dmxl1 ensured gfi gnal gnl3l gpr65 gtf2h3 il6st jem knocked lamp1 megakaryocytic mycbp pld1 rac3 rbbp6 reserve rigorous smc3 tmem30 tpr znf292
Tagcloud (Difference) ?		arnt2 asked camk2g cstb ctgf downregulated dr1 epas1 globin gna11 hif1a hypoxic khsrp mars multitude neuroglobin neuroprotection ngb o4 ogd pea15 r4 reoxygenation rest spatially temporally tg wt	1b atr atxn3 bcl11b cdkn1a cep290 cxcl5 dmxl1 ensured gfi gnal gnl3l gpr65 gtf2h3 jem knocked lamp1 megakaryocytic mycbp pld1 rac3 rbbp6 reserve rigorous smc3 tmem30 tpr znf292
Tagcloud (Intersection) ?		il6st